DGIdb - ARG2 Gene Record

ARG2 384

Alternate Names:

384
ARGINASE 2
ARG2
107830
664
ENSG00000081181
OTTHUMG00000171807
BE0000758
P78540
1245
Arginase II
Kidney-type arginase
T36806

Gene Info:

Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	Arginase
GuideToPharmacology Gene Category ID	250

(0 More Sources)

Gene Categories: Category Details

ENZYME

Publications:

Hood et al., 2007, Evolutionary changes in the fungal carbamoyl-phosphate synthetase small subunit gene and its associated upstream open reading frame., Fungal Genet. Biol.
Topal et al., 2006, Mitochondrial arginase II modulates nitric-oxide synthesis through nonfreely exchangeable L-arginine pools in human endothelial cells., J. Pharmacol. Exp. Ther.
Rodriguez et al., 2003, L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes., J. Immunol.
Bussière et al., 2005, Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation., J. Biol. Chem.
Nissim et al., 2005, The role of mitochondrially bound arginase in the regulation of urea synthesis: studies with [U-15N4]arginine, isolated mitochondria, and perfused rat liver., J. Biol. Chem.
Levillain et al., 2005, Testosterone down-regulates ornithine aminotransferase gene and up-regulates arginase II and ornithine decarboxylase genes for polyamines synthesis in the murine kidney., Endocrinology
Levillain et al., 2004, Ornithine metabolism in male and female rat kidney: mitochondrial expression of ornithine aminotransferase and arginase II., Am. J. Physiol. Renal Physiol.

ORNITHINE ARG2

Interaction Score: 15.49

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12874210 15548540 15753084 15539552 14871882

Sources:
DrugBank
ARGININE ARG2

Interaction Score: 8.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16979358 16801455

Sources:
DrugBank

Ensembl: ENSG00000081181
- Version: 101_38
Alternate Names:

ARG2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
GuideToPharmacology: 384
- Version: 29-September-2020
Alternate Names:

664 HUGO Gene ID

664 HUGO Gene Symbol

arginase 2 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Arginase

GuideToPharmacology Gene Category ID 250

Gene Categories:

ENZYME

Publications:

DrugBank: BE0000758

Version: 5.1.7

Alternate Names:

ARG2 DrugBank Gene Name

P78540 UniProt Accession

384 Entrez Gene Id

Gene Info:

Publications:

Bussière et al., 2005, Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation., J. Biol. Chem.

Levillain et al., 2005, Testosterone down-regulates ornithine aminotransferase gene and up-regulates arginase II and ornithine decarboxylase genes for polyamines synthesis in the murine kidney., Endocrinology

Rodriguez et al., 2003, L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes., J. Immunol.

TTD: Kidney-type arginase
- Version: 2020.06.01
Alternate Names:

ARG2 TTD Gene Abbreviation

T36806 TTD Target ID

Gene Info:

Publications: