• Interaction Score: 5.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    20890287


    Sources:
    JAX-CKB

  • Interaction Score: 0.85

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colon cancer
    Response Type predicted – sensitive
    Approval Status Preclinical - Pdx

    PMIDs:
    22753465


    Sources:
    JAX-CKB

  • Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Response Type no benefit
    Evidence Type Actionable
    Approval Status Preclinical

    PMIDs:
    26206338


    Sources:
    JAX-CKB

  • Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Evidence Type Actionable
    Approval Status Preclinical
    Response Type sensitive

    PMIDs:
    19755659


    Sources:
    JAX-CKB

  • Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    25261369


    Sources:
    JAX-CKB

  • Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Fluorouracil + Leucovorin + Trastuzumab
    Indication/Tumor Type rectum adenocarcinoma
    Response Type no benefit

    PMIDs:
    27626067


    Sources:
    JAX-CKB

  • Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colon cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    22399804


    Sources:
    JAX-CKB

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Clinical Study

    PMIDs:
    27004155


    Sources:
    JAX-CKB

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    21531761


    Sources:
    JAX-CKB

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Evidence Type Actionable
    Approval Status Clinical Study
    Response Type no benefit

    PMIDs:
    27626067


    Sources:
    JAX-CKB

  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12856637


    Sources:
    NCI

  • Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colon cancer
    Response Type sensitive
    Approval Status Preclinical


    Sources:
    JAX-CKB

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Evidence Type Actionable
    Approval Status Preclinical - Cell line xenograft
    Response Type sensitive

    PMIDs:
    17909047


    Sources:
    JAX-CKB

  • Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy BEZ235 + Binimetinib
    Indication/Tumor Type colorectal cancer
    Response Type sensitive

    PMIDs:
    26206338


    Sources:
    JAX-CKB

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Erlotinib + Ibuprofen
    Indication/Tumor Type colorectal cancer
    Response Type sensitive

    PMIDs:
    17909047


    Sources:
    JAX-CKB

  • Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colon cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    20811697


    Sources:
    JAX-CKB

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    17909047


    Sources:
    JAX-CKB

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type sensitive
    Approval Status Preclinical

    PMIDs:
    20473900


    Sources:
    JAX-CKB

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Fluorouracil + Leucovorin + Trastuzumab
    Indication/Tumor Type rectum adenocarcinoma
    Response Type no benefit

    PMIDs:
    27626067


    Sources:
    JAX-CKB