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AKT1S1 Gene Record

  • Summary
  • Interactions
  • Claims
  • AKT1S1 84335 Druggable Genome

    Alternate Names:

    84335
    AKT1 SUBSTRATE 1
    AKT1S1
    Lobe
    PRAS40
    610221
    28426
    ENSG00000204673
    OTTHUMG00000150246
    TORC1/2
    Q96B36
    Proline-rich AKT1 substrate 1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUGGABLE GENOME

    Publications:

    Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.
  • OSI-027   AKT1S1

    Interaction Score: 1.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • GEDATOLISIB   AKT1S1

    Interaction Score: 1.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20166697


    Sources:
    DTC

  • AZD-8055   AKT1S1

    Interaction Score: 1.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • SAPANISERTIB   AKT1S1

    Interaction Score: 0.74

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Ensembl: ENSG00000204673

    • Version: 101_38

    Alternate Names:
    AKT1S1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: AKT1S1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.

  • HingoraniCasas: ENSG00000204673

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000204673 Gene Symbol
    AKT1S1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • MyCancerGenome: AKT1S1

    • Version: 20-Jun-2017

    Alternate Names:
    84335 Entrez Gene Id
    AKT1S1 MyCancerGenome Gene Symbol
    TORC1/2 MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • Pharos: AKT1S1

    • Version: 01-February-2022

    Alternate Names:
    Proline-rich AKT1 substrate 1 Gene Name
    Q96B36 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21