DGIdb - AKT1S1 Gene Record

AKT1S1 84335 Druggable Genome

Alternate Names:

84335
AKT1 SUBSTRATE 1
AKT1S1
Lobe
PRAS40
610221
28426
ENSG00000204673
OTTHUMG00000150246
TORC1/2
Q96B36
Proline-rich AKT1 substrate 1

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

KINASE
DRUGGABLE GENOME

Publications:

Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.

OSI-027 AKT1S1

Interaction Score: 1.55

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
GEDATOLISIB AKT1S1

Interaction Score: 1.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20166697

Sources:
DTC
AZD-8055 AKT1S1

Interaction Score: 1.03

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
SAPANISERTIB AKT1S1

Interaction Score: 0.74

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome

Ensembl: ENSG00000204673
- Version: 101_38
Alternate Names:

AKT1S1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DTC: AKT1S1

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.

HingoraniCasas: ENSG00000204673
- Version: 31-May-2017
Alternate Names:

ENSG00000204673 Gene Symbol

AKT1S1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
MyCancerGenome: AKT1S1
- Version: 20-Jun-2017
Alternate Names:

84335 Entrez Gene Id

AKT1S1 MyCancerGenome Gene Symbol

TORC1/2 MyCancerGenome Reported Gene Name

Gene Info:

Publications:
Pharos: AKT1S1
- Version: 01-February-2022
Alternate Names:

Proline-rich AKT1 substrate 1 Gene Name

Q96B36 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

84335	Entrez Gene Id
AKT1S1	MyCancerGenome Gene Symbol
TORC1/2	MyCancerGenome Reported Gene Name

AKT1S1 Gene Record

AKT1S1 84335 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

OSI-027 AKT1S1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

GEDATOLISIB AKT1S1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20166697

Sources: DTC

AZD-8055 AKT1S1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

SAPANISERTIB AKT1S1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

Ensembl: ENSG00000204673

Alternate Names: AKT1S1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DTC: AKT1S1

Alternate Names:

Gene Info:

Publications: Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.

HingoraniCasas: ENSG00000204673

Alternate Names: ENSG00000204673 Gene Symbol AKT1S1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

MyCancerGenome: AKT1S1

Alternate Names: 84335 Entrez Gene Id AKT1S1 MyCancerGenome Gene Symbol TORC1/2 MyCancerGenome Reported Gene Name

Gene Info:

Publications:

Pharos: AKT1S1

Alternate Names: Proline-rich AKT1 substrate 1 Gene Name Q96B36 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

n/a

PMIDs:
20166697

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Alternate Names:

AKT1S1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

Venkatesan et al., 2010, Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor., J. Med. Chem.

Alternate Names:

ENSG00000204673 Gene Symbol

AKT1S1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

84335 Entrez Gene Id

AKT1S1 MyCancerGenome Gene Symbol

TORC1/2 MyCancerGenome Reported Gene Name

Alternate Names:

Proline-rich AKT1 substrate 1 Gene Name

Q96B36 UniProt ID

Gene Categories:

KINASE