• Interaction Score: 14.72

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> inhibition of recombinant human aldose reductase expressed in <i>E coli</i>.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    10592235


  • Interaction Score: 9.81

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> inhibition of recombinant human aldehyde reductase
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    10592235


  • Interaction Score: 9.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16870454


    Sources:
    NCI

  • Interaction Score: 9.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name ranirestat, AS-3201
    Novel drug target Novel Target

    PMIDs:
    None found


  • Interaction Score: 9.81

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    TTD

  • Interaction Score: 7.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

  • Interaction Score: 4.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 4.91

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> inhibition of recombinant human aldehyde reductase
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 4.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 3.68

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

  • Interaction Score: 2.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9057855


    Sources:
    NCI

  • Interaction Score: 1.91

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

  • Interaction Score: 1.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD