• Interaction Score: 5.04

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name amibegron, SR 58611
    Specific Action of the Ligand Full agonist

    PMIDs:
    None found


  • Interaction Score: 5.04

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Beta-3 adrenergic receptor agonist
    Direct Interaction yes
    Specific Action of the Ligand Agonist

    PMIDs:
    None found


  • Interaction Score: 5.04

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Beta-3 adrenergic receptor agonist
    Direct Interaction yes
    Trial Name KUC-7483

    PMIDs:
    None found


  • Interaction Score: 2.52

    Interaction Types & Directionality:
    agonist (activating)
    antagonist (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Radioligand binding
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

  • Interaction Score: 2.24

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name solabegron, GW 427353
    Novel drug target Novel Target
    Specific Action of the Ligand Agonist

  • Interaction Score: 2.1

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name YM-178
    Mechanism of Interaction Beta-3 adrenergic receptor agonist

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Beta-3 adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.68

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Beta-3 adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.68

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    TTD

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Beta-3 adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    24900353


  • Interaction Score: 1.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6125169


    Sources:
    TTD

  • Interaction Score: 1.05

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

  • Interaction Score: 0.84

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Full agonist

    PMIDs:
    None found


  • Interaction Score: 0.84

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.56

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.56

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    None found


  • Interaction Score: 0.56

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor beta antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.56

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.42

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.34

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor beta agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.34

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 0.34

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Adrenergic receptor beta antagonist

    PMIDs:
    None found


  • Interaction Score: 0.3

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? True

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.21

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.17

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.1

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Adrenergic receptor agonist

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor beta antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.06

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19193342


    Sources:
    PharmGKB