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ADAMTS1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ADAMTS1 9510 Druggable Genome

    Alternate Names:

    9510
    ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF 1
    ADAMTS1
    C3-C5
    METH1
    605174
    217
    ENSG00000154734
    OTTHUMG00000078688
    PA24536
    ADAMTS-1 PRECURSOR (EC 3.4.24.-) (A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1) (ADAM-TS 1) (ADAM-TS1) (METH-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UHI8]
    KIAA1346

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    NEUTRAL ZINC METALLOPEPTIDASE
    PROTEASE
    DRUGGABLE GENOME

    Publications:

    Sabatine MS et al., 2008, Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy., Arterioscler Thromb Vasc Biol
  • PRAVASTATIN   ADAMTS1

    Interaction Score: 3.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18174457


    Sources:
    PharmGKB

  • Ensembl: ENSG00000154734

    • Version: 101_38

    Alternate Names:
    ADAMTS1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000154734

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000154734 Ensembl Gene Id
    ADAMTS-1 PRECURSOR (EC 3.4.24.-) (A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1) (ADAM-TS 1) (ADAM-TS1) (METH-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UHI8] Description
    ADAMTS1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: ADAMTS1

    • Version: 18-August-2020

    Alternate Names:
    PA24536 PharmGKB ID

    Gene Info:

    Publications:
    Sabatine MS et al., 2008, Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy., Arterioscler Thromb Vasc Biol
    Peters BJ et al., 2010, Variants of ADAMTS1 modify the effectiveness of statins in reducing the risk of myocardial infarction., Pharmacogenet Genomics

  • HingoraniCasas: ENSG00000154734

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000154734 Gene Symbol
    ADAMTS1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: ADAMTS1

    • Version: 01-February-2022

    Alternate Names:
    KIAA1346 GO Gene Synonym
    METH1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    NEUTRAL ZINC METALLOPEPTIDASE

    Publications:

  • dGene: ADAMTS1

    • Version: 27-Jun-2013

    Alternate Names:
    9510 Gene ID
    C3-C5 dGene Synonym
    METH1 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21