• ADAM10 102 Druggable Genome

    Alternate Names:

    102
    ADAM METALLOPEPTIDASE DOMAIN 10
    ADAM10
    AD10
    AD18
    CD156c
    CDw156
    HsT18717
    MADM
    RAK
    kuz
    602192
    188
    ENSG00000137845
    OTTHUMG00000132633
    1658
    O14672
    BE0002404
    NM_001110
    NP_001101
    ADAM 10 PRECURSOR (EC 3.4.24.81) (A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 10) (MAMMALIAN DISINTEGRIN-METALLOPROTEASE) (KUZBANIAN PROTEIN HOMOLOG). [SOURCE:UNIPROT/SWISSPROT;ACC:O14672]
    Mammalian disintegrin-metalloprotease
    T31902

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:3.4.24.81
    GuideToPharmacology Gene Category Name M12: Astacin/Adamalysin
    GuideToPharmacology Gene Category ID 739
    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    CELL SURFACE
    NEUTRAL ZINC METALLOPEPTIDASE
    PROTEASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 9.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.51

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26192023


    Sources:
    DTC

  • Interaction Score: 1.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Measured in an <i>in vitro</i> assay.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    ADAM10 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    ADAM10 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.24.81

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ADAM 10 PRECURSOR (EC 3.4.24.81) (A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 10) (MAMMALIAN DISINTEGRIN-METALLOPROTEASE) (KUZBANIAN PROTEIN HOMOLOG). [SOURCE:UNIPROT/SWISSPROT;ACC:O14672] Description
    ENSG00000137845 Ensembl Gene Id
    ADAM10 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    188 HUGO Gene ID
    188 HUGO Gene Symbol
    ADAM metallopeptidase domain 10 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name M12: Astacin/Adamalysin
    GuideToPharmacology Gene Category ID 739

    Gene Categories:
    ENZYME

    Publications:

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000137845 Gene Symbol
    ADAM10 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000137845 Ensembl Gene ID
    CD156c Human Protein Atlas Gene Synonym
    HsT18717 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, ENZYME, TRANSPORTER

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    KUZ GO Gene Synonym
    MADM GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, NEUTRAL ZINC METALLOPEPTIDASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    102 Gene ID
    AD10 dGene Synonym
    CD156c dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: 5.1.7

    Alternate Names:
    ADAM10 DrugBank Gene Name
    O14672 UniProt Accession
    102 Entrez Gene Id

    Gene Info:

    Publications:

  • Alternate Names:
    ADAM10 TTD Gene Abbreviation
    T31902 TTD Target ID

    Gene Info:

    Publications: