1636 |
ANGIOTENSIN I CONVERTING ENZYME |
ACE |
ACE1 |
CD143 |
DCP |
DCP1 |
106180 |
2707 |
ENSG00000159640 |
ENSG00000264813 |
OTTHUMG00000154927 |
OTTHUMG00000178900 |
BE0000221 |
P12821 |
ACE_HUMAN |
CD_antigen=CD143 |
Angiotensin-converting enzyme |
Angiotensin-converting enzyme, soluble form |
Dipeptidyl carboxypeptidase I |
Kininase II |
1613 |
PA139 |
ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM PRECURSOR (EC 3.4.15.1) (ACE) (DIPEPTIDYL CARBOXYPEPTIDASE I) (KININASE II) (CD143 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P12821] |
P01019 |
ENSG00000135744 |
ANGT_HUMAN |
183 |
NP_000780|NP_001171528|NP_690043 |
NM_000789|NM_001178057|NM_152830 |
T82577 |
AC113554.1 |
ICH |
MVCD3 |
Target Class | Enzymes |
Target Subclass | EC:3.4.15 |
Target Class | Other |
Target Subclass | 3.4.15 |
Transmembrane Helix Count | 1 |
Target Main Class | Enzymes |
Human Readable Name | DRUGGABLE GENOME |
Target Subclass | Ligand |
Target Subclass | Hormone |
Target Main Class | Other |
GuideToPharmacology Gene Category Name | M2: Angiotensin-converting (ACE and ACE2) |
GuideToPharmacology Gene Category ID | 741 |
Gene Biotype | PROTEIN_CODING |
NEUTRAL ZINC METALLOPEPTIDASE |
PROTEASE |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
ENZYME |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Direct Interaction? | True |
inhibitor (inhibitory) |
Trial Name | trandolapril,Gopten, Mavik, Odrik |
Novel drug target | Established target |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Endogenous Drug? | False |
Direct Interaction? | True |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Direct Interaction? | True |
Endogenous Drug? | False |
n/a |
Trial Name | - |
Novel drug target | Established target |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
n/a |
Trial Name | ilepatril, AVE-7688 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Angiotensin-converting enzyme inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
AC113554.1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ACE | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
P01019 | Uniprot Accession |
ACE | Gene Symbol |
183 | Entrez Gene Id |
Target Subclass | Ligand |
Target Subclass | Hormone |
Target Main Class | Other |
ACE | Display Id |
ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM PRECURSOR (EC 3.4.15.1) (ACE) (DIPEPTIDYL CARBOXYPEPTIDASE I) (KININASE II) (CD143 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P12821] | Description |
ENSG00000159640 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
ACE | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.4.15 |
Target Class | Other |
1636 | Entrez Gene Id |
ACE | Gene Symbol |
ENSG00000159640 | Ensembl Gene Id |
Target Subclass | 3.4.15 |
Transmembrane Helix Count | 1 |
Target Main Class | Enzymes |
2707 | HUGO Gene ID |
2707 | HUGO Gene Symbol |
angiotensin I converting enzyme | HUGO Gene Name |
GuideToPharmacology Gene Category Name | M2: Angiotensin-converting (ACE and ACE2) |
GuideToPharmacology Gene Category ID | 741 |
ENZYME |
PA139 | PharmGKB ID |
ACE | DrugBank Gene Name |
P12821 | UniProt Accession |
1636 | Entrez Gene Id |
ENSG00000159640 | Gene Symbol |
ACE | Ensembl Id |
DRUGGABLE GENOME |
ENSG00000264813 | Gene Symbol |
Ensembl Id |
DRUGGABLE GENOME |
DCP1 | GENE_SYMBOL |
ACE | GENE_SYMBOL |
Angiotensin-converting enzyme | UNIPROT |
P12821 | UniProt ID |
Angiotensin-converting enzyme | Gene Name |
ENZYME |
DCP | GO Gene Synonym |
DCP1 | GO Gene Synonym |
NEUTRAL ZINC METALLOPEPTIDASE, EXTERNAL SIDE OF PLASMA MEMBRANE |
1636 | Gene ID |
ACE1 | dGene Synonym |
CD143 | dGene Synonym |
PROTEASE |
ACE | TTD Gene Abbreviation |
T82577 | TTD Target ID |