DGIdb - AANAT Gene Record

AANAT 15

Alternate Names:

15
ARALKYLAMINE N-ACETYLTRANSFERASE
AANAT
DSPS
SNAT
600950
19
ENSG00000129673
OTTHUMG00000180179
BE0004584
Q16613
Serotonin N-acetyltransferase
BE0009154
F1T0I5

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

ENZYME

Publications:

Uz et al., 2005, Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum., Neuroscience
Steinlechner et al., 1984, Comparison of the effects of beta-adrenergic agents on pineal serotonin N-acetyltransferase activity and melatonin content in two species of hamsters., J. Pineal Res.
Itoh et al., 1995, Melatonin and arylalkylamine N-acetyltransferase activity in the silkworm, Bombyx mori., Mol. Cell. Endocrinol.
Ganguly et al., 2005, Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205., Proc. Natl. Acad. Sci. U.S.A.
Johnston et al., 2004, Rhythmic melatonin secretion does not correlate with the expression of arylalkylamine N-acetyltransferase, inducible cyclic amp early repressor, period1 or cryptochrome1 mRNA in the sheep pineal., Neuroscience
Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics

MELATONIN AANAT

Interaction Score: 1.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8674865 15644438 15026119

Sources:
NCI
ISOPROTERENOL AANAT

Interaction Score: 0.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6152777

Sources:
NCI
FLUOXETINE AANAT

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15994025

Sources:
NCI
CANNABIDIOL AANAT

Interaction Score: 0.53

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
26264914

Sources:
DrugBank
NABIXIMOLS AANAT

Interaction Score: 0.52

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
26264914

Sources:
DrugBank

Ensembl: ENSG00000129673
- Version: 101_38
Alternate Names:

AANAT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
DrugBank: BE0009154
- Version: 5.1.7
Alternate Names:

AANAT DrugBank Gene Name

F1T0I5 UniProt Accession

15 Entrez Gene Id

Gene Info:

Publications:

Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics

DrugBank: BE0004584

Version: 5.1.7

Alternate Names:

AANAT DrugBank Gene Name

Q16613 UniProt Accession

15 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: AANAT

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Uz et al., 2005, Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum., Neuroscience

Benyassi et al., 2001, Glucocorticoid receptors and serotonin N-acetyltransferase activity in the fish pineal organ., Neuroreport

Steinlechner et al., 1984, Comparison of the effects of beta-adrenergic agents on pineal serotonin N-acetyltransferase activity and melatonin content in two species of hamsters., J. Pineal Res.

Pharos: AANAT
- Version: 03-September-2020
Alternate Names:

Serotonin N-acetyltransferase Gene Name

Q16613 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

AANAT	DrugBank Gene Name
F1T0I5	UniProt Accession
15	Entrez Gene Id

AANAT Gene Record

AANAT 15

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

MELATONIN AANAT

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8674865 15644438 15026119

Sources: NCI

ISOPROTERENOL AANAT

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6152777

Sources: NCI

FLUOXETINE AANAT

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15994025

Sources: NCI

CANNABIDIOL AANAT

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 26264914

Sources: DrugBank

NABIXIMOLS AANAT

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 26264914

Sources: DrugBank

Ensembl: ENSG00000129673

Alternate Names: AANAT Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0009154

Alternate Names: AANAT DrugBank Gene Name F1T0I5 UniProt Accession 15 Entrez Gene Id

Gene Info:

Publications: Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics

DrugBank: BE0004584

Alternate Names: AANAT DrugBank Gene Name Q16613 UniProt Accession 15 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: AANAT

Alternate Names:

Gene Info:

Pharos: AANAT

Alternate Names: Serotonin N-acetyltransferase Gene Name Q16613 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
8674865 15644438 15026119

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
6152777

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15994025

Sources:
NCI

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
26264914

Sources:
DrugBank

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
26264914

Sources:
DrugBank

Alternate Names:

AANAT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

AANAT DrugBank Gene Name

F1T0I5 UniProt Accession

15 Entrez Gene Id

Publications:

Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics

Alternate Names:

AANAT DrugBank Gene Name

Q16613 UniProt Accession

15 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

Serotonin N-acetyltransferase Gene Name

Q16613 UniProt ID

Gene Categories:

ENZYME