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AANAT Gene Record

  • Summary
  • Interactions
  • Claims
  • AANAT 15

    Alternate Names:

    15
    ARALKYLAMINE N-ACETYLTRANSFERASE
    AANAT
    DSPS
    SNAT
    600950
    19
    ENSG00000129673
    OTTHUMG00000180179
    BE0004584
    Q16613
    Serotonin N-acetyltransferase
    BE0009154
    F1T0I5

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Uz et al., 2005, Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum., Neuroscience
    Steinlechner et al., 1984, Comparison of the effects of beta-adrenergic agents on pineal serotonin N-acetyltransferase activity and melatonin content in two species of hamsters., J. Pineal Res.
    Itoh et al., 1995, Melatonin and arylalkylamine N-acetyltransferase activity in the silkworm, Bombyx mori., Mol. Cell. Endocrinol.
    Ganguly et al., 2005, Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205., Proc. Natl. Acad. Sci. U.S.A.
    Johnston et al., 2004, Rhythmic melatonin secretion does not correlate with the expression of arylalkylamine N-acetyltransferase, inducible cyclic amp early repressor, period1 or cryptochrome1 mRNA in the sheep pineal., Neuroscience
    Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics
  • MELATONIN   AANAT

    Interaction Score: 1.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8674865 15644438 15026119


    Sources:
    NCI

  • ISOPROTERENOL   AANAT

    Interaction Score: 0.67

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6152777


    Sources:
    NCI

  • FLUOXETINE   AANAT

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15994025


    Sources:
    NCI

  • CANNABIDIOL   AANAT

    Interaction Score: 0.53

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26264914


    Sources:
    DrugBank

  • NABIXIMOLS   AANAT

    Interaction Score: 0.52

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26264914


    Sources:
    DrugBank

  • Ensembl: ENSG00000129673

    • Version: 101_38

    Alternate Names:
    AANAT Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0009154

    • Version: 5.1.7

    Alternate Names:
    AANAT DrugBank Gene Name
    F1T0I5 UniProt Accession
    15 Entrez Gene Id

    Gene Info:

    Publications:
    Ibeas Bih C et al., 2015, Molecular Targets of Cannabidiol in Neurological Disorders., Neurotherapeutics

  • DrugBank: BE0004584

    • Version: 5.1.7

    Alternate Names:
    AANAT DrugBank Gene Name
    Q16613 UniProt Accession
    15 Entrez Gene Id

    Gene Info:

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

  • NCI: AANAT

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Uz et al., 2005, Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum., Neuroscience
    Benyassi et al., 2001, Glucocorticoid receptors and serotonin N-acetyltransferase activity in the fish pineal organ., Neuroreport
    Steinlechner et al., 1984, Comparison of the effects of beta-adrenergic agents on pineal serotonin N-acetyltransferase activity and melatonin content in two species of hamsters., J. Pineal Res.

  • Pharos: AANAT

    • Version: 03-September-2020

    Alternate Names:
    Serotonin N-acetyltransferase Gene Name
    Q16613 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21