• ZOTEPINE chembl:CHEMBL285802 Approved

    Alternate Names:

    ZOTEPINE
    ZOLEPTIL 25
    ZOLEPTIL 100
    ZOLEPTIL 50
    ZOLEPTIL®
    2-CHLORO-11-(2-(DIMETHYLAMINO)ETHOXY)DIBENZO(B,F)THIEPIN
    drugbank:09225
    chemidplus:26615-21-4
    rxcui:40003
    pubchem.compound:5736
    chembl:CHEMBL285802

    Drug Info:

    Drug Groups approved
    Drug Groups investigational
    Drug Groups withdrawn
    Drug Type small molecule
    Drug Categories antidepressive agents
    Drug Categories antipsychotic agents
    Drug Categories antipsychotic agents (second generation [atypical])
    Drug Categories central nervous system agents
    Drug Categories central nervous system depressants
    Drug Categories cytochrome p-450 cyp1a2 substrates
    Drug Categories cytochrome p-450 cyp3a substrates
    Drug Categories cytochrome p-450 cyp3a4 substrates
    Drug Categories cytochrome p-450 substrates
    Drug Categories dopamine antagonists
    Drug Categories dopamine d2 receptor antagonists
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories nervous system
    Drug Categories neurotoxic agents
    Drug Categories psycholeptics
    Drug Categories psychotropic drugs
    Drug Categories serotonergic drugs shown to increase risk of serotonin syndrome
    Drug Categories serotonin 5-ht2 receptor antagonists
    Drug Categories serotonin agents
    Drug Categories serotonin receptor antagonists
    Drug Categories sulfur compounds
    Drug Categories thiepins
    Drug Categories tranquilizing agents
    (0 More Sources)
  • Interaction Score: 0.14

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inverse agonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Inverse agonist

    PMIDs:
    None found


  • Interaction Score: 0.1

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.06

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 0.05

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.05

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.05

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.04

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.04

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 0.03

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inverse agonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DrugBank