WARFARIN Drug Record
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WARFARIN chembl:CHEMBL1464 Approved
Alternate Names:
WARFARIN NSC-59813 PANWARFIN 4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)COUMARIN MAREVAN® ZOOCOUMARIN COUMAFENE COUMADIN® rxcui:11289 chembl:CHEMBL1464 pubchem.compound:54678486 chemidplus:81-81-2 drugbank:00682 Drug Info:
Year of Approval approved before 1982 Drug Class anticoagulants Drug Categories rodenticides FDA Approval Approved before 1982 Drug Class small molecule Drug Indications Anticoagulants Drug Categories compounds used in a research, industrial, or household setting Drug Categories cytochrome p-450 cyp1a2 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c18 substrates Drug Categories cytochrome p-450 cyp2c18 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c19 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c19 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 cyp2c8 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c9 inducers Drug Categories cytochrome p-450 cyp2c9 inducers (weak) Drug Categories cytochrome p-450 cyp3a inducers Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 cyp3a4 inducers Drug Categories cytochrome p-450 cyp3a4 inducers (weak) Drug Categories cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 enzyme inducers Drug Categories cytochrome p-450 enzyme inhibitors Drug Categories cytochrome p-450 substrates Drug Categories drugs that are mainly renally excreted Drug Categories drugs that are mainly renally excreted with narrow therapeutic index Drug Categories heterocyclic compounds, fused-ring Drug Categories narrow therapeutic index drugs Drug Categories vitamin k inhibitors Publications:
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target Specific Action of the Ligand Inhibition PMIDs:
17413769 17510308 11752352 17161452 17275317 17653141 31653973 31395958 29781049 29577257 29432897 29396738 29298995 29054760 28689179 28429387 28382498 28262345 28049362 28033245 27581200 27488176 27262824 27121899 26777610 26445138 26433837 26257249 26223945 26219158 25989350 25769357 25594941 25521356 25519826 25312789 25244877 25084205 25042728 25026456 25001883 24919870 24728385 24474498 24330000 24029542 24019055 23949431 23932037 23774101 23602689 23423913 23279643 23208322 23183958 23159229 23104259 23061746 22990331 22854539 22676192 22616655 22592842 22571356 22549502 22534826 22528326 22349464 22248286 22075505 22040439 22010099 21981797 21900891 21635147 21383771 21326313 21318593 21273734 21185752 21176721 21174619 21148049 21110192 20833980 20833655 20615525 20585834 20421126 20410877 20386359 20339978 20203262 20072124 19875892 19874474 19794411 19745563 19582440 19387626 19297219 19177029 19135231 19077919 18950464 18752379 18698879 18690342 18574025 18542936 18466099 18240904 18234403 18030307 17989110 17456829 17391071 17329985 17110455 17031720 16821005 16611750 11127854 9684798 17906972 17189218 17124101 17112295 17111199 17049586 17042764 17015052 16983400 16960144 16890578 16888441 16847429 16815313 16815312 16676068 16611310 16580898 16493479 16432637 16270629 16141794 15947090 15938684 15930419 15888487 15883587 15865594 15790782 15597574 15358623 14765195 14765194 14676821 12931134 11926893
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Interaction Types & Directionality:
n/a Interaction Info:
Trial Name - Novel drug target Established target
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Alternate Names:
81-81-2 CAS Number Apo-warfarin Drug Brand Coumadin Drug Brand Drug Info:
Drug Groups approved Drug Type small molecule Drug Categories 4-hydroxycoumarins Publications:
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- Version: January-2014
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Drug Info:
Drug Indications Anticoagulants Drug Class small molecule FDA Approval Approved before 1982 Publications:
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Drug Info:
Drug Class anticoagulants Year of Approval approved before 1982 Publications:
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C945 NCI drug code Drug Info:
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CHEMBL1464 ChEMBL Drug ID Drug Info:
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D0E3OF TTD Drug ID Drug Info:
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- Version: ChEMBL_27
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Drug Info:
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Drug Info:
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- Version: 29-September-2020
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Drug Info:
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