LU AA21004 |
LU-AA21004 |
BRINTELLIX |
LUAA21004 |
VORTIOXETINE |
VORTIOXÉTINE |
VORTIOXETINA |
TRINTELLIX |
VORTIOXETINUM |
chembl:CHEMBL2104993 |
rxcui:1455099 |
pubchem.compound:9966051 |
drugbank:09068 |
chemidplus:508233-74-7 |
FDA Approval | not approved |
Drug Class | small molecule |
Drug Indications | antidepressant |
Drug Categories | serotonin 5-ht3 receptor antagonists |
Drug Groups | investigational |
Drug Categories | agents that produce hypertension |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a5 substrates |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | drugs that are mainly renally excreted |
Drug Categories | piperazines |
Drug Categories | serotonergic drugs shown to increase risk of serotonin syndrome |
Drug Categories | serotonin receptor antagonists |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | True |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | False |
agonist (activating) |
partial agonist (activating) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Partial agonist |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | Lu AA21004 |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Lu AA21004 |
Specific Action of the Ligand | Inhibition |
agonist (activating) |
Trial Name | Lu AA21004 |
Novel drug target | Established target |
Specific Action of the Ligand | Partial agonist |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | False |
antagonist (inhibitory) |
Specific Action of the Ligand | Antagonist |
Endogenous Drug? | False |
Direct Interaction? | False |
VORTIOXETINE | DrugBank Drug Name |
508233-74-7 | CAS Number |
Brintellix | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | investigational |
Drug Indications | antidepressant |
Drug Class | small molecule |
FDA Approval | not approved |
VORTIOXETINE | GuideToPharmacology Ligand Name |
D03WEX | TTD Drug ID |