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VOLANESORSEN SODIUM Drug Record

  • Summary
  • Interactions
  • Claims
  • VOLANESORSEN SODIUM chembl:CHEMBL3544989

    Alternate Names:

    VOLANESORSEN SODIUM
    SALT
    ISIS 304801 SODIUM SALT
    ISIS-304801
    ISIS-304801 SODIUM SALT
    ISIS-304801 SODIUM

    Drug Info:

    (0 More Sources)

    Publications:

    Couthon et al., 1997, High salt concentrations induce dissociation of dimeric rabbit muscle creatine kinase. Physico-chemical characterization of the monomeric species., Biochim. Biophys. Acta
    Miller et al., 1996, Mutational analysis of the role of the N terminus of actin in actomyosin interactions. Comparison with other mutant actins and implications for the cross-bridge cycle., Biochemistry
    Ni et al., 2001, Effect of salt loading on nitric oxide synthase expression in normotensive rats., Am. J. Hypertens.
    Morisset et al., 1997, Localization of rat pancreatitis-associated protein during bile salt-induced pancreatitis., Gastroenterology
    Wang et al., 2003, Effects of uroguanylin, an intestinal natriuretic peptide, on tubuloglomerular feedback., Hypertens. Res.
    Carrithers et al., 2002, Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine., Regul. Pept.
    Carrithers et al., 1999, Renal effects of uroguanylin and guanylin in vivo., Braz. J. Med. Biol. Res.
    Tamura et al., 1999, Renin-angiotensin system and fibronectin gene expression in Dahl Iwai salt-sensitive and salt-resistant rats., J. Hypertens.
    Kita et al., 1999, Marked increase of guanylin secretion in response to salt loading in the rat small intestine., Am. J. Physiol.
    Porter et al., 1997, Broad-spectrum antimicrobial activity of human intestinal defensin 5., Infect. Immun.
    Harvima et al., 1988, The allosteric effect of salt on human mast cell tryptase., Biochim. Biophys. Acta
    Nissen et al., 1991, Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein., J. Biol. Chem.
    Skrabal et al., 1989, Inverse regulation of alpha-2 and beta-2 adrenoceptors in salt-sensitive hypertension: an hypothesis., Life Sci.
    El-Dahr et al., 2000, Fetal ontogeny and role of metanephric bradykinin B2 receptors., Pediatr. Nephrol.
  • VOLANESORSEN SODIUM   GUCA2B

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12924626 12137970 10559834


    Sources:
    NCI

  • VOLANESORSEN SODIUM   DEFA5

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9169780


    Sources:
    NCI

  • VOLANESORSEN SODIUM   REG3A

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9024308


    Sources:
    NCI

  • VOLANESORSEN SODIUM   TPSB2

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3048411


    Sources:
    NCI

  • VOLANESORSEN SODIUM   CKM

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9187248


    Sources:
    NCI

  • VOLANESORSEN SODIUM   GUCA2A

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10564101


    Sources:
    NCI

  • VOLANESORSEN SODIUM   HMGB1

    Interaction Score: 0.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1939057


    Sources:
    NCI

  • VOLANESORSEN SODIUM   MYO9B

    Interaction Score: 0.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8987990


    Sources:
    NCI

  • VOLANESORSEN SODIUM   BDKRB2

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10775071


    Sources:
    NCI

  • VOLANESORSEN SODIUM   NOS1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11243307


    Sources:
    NCI

  • VOLANESORSEN SODIUM   AGTR1

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10100098


    Sources:
    NCI

  • VOLANESORSEN SODIUM   ADRB2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2557514


    Sources:
    NCI

  • NCI: SALT

    • Version: 14-September-2017

    Alternate Names:
    C29974 NCI drug code
    C994 NCI drug code

    Drug Info:

    Publications:
    Couthon et al., 1997, High salt concentrations induce dissociation of dimeric rabbit muscle creatine kinase. Physico-chemical characterization of the monomeric species., Biochim. Biophys. Acta
    Ni et al., 2001, Effect of salt loading on nitric oxide synthase expression in normotensive rats., Am. J. Hypertens.
    Porter et al., 1997, Broad-spectrum antimicrobial activity of human intestinal defensin 5., Infect. Immun.

  • ChemblDrugs: chembl:CHEMBL3544989

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21