DGIdb - URIDINE Drug Record

URIDINE chembl:CHEMBL100259

Alternate Names:

URIDINE
NSC-20256

Drug Info:

Drug Categories	ribonucleosides
Drug Categories	pyrimidines
Drug Categories	pyrimidine nucleosides
Drug Categories	nucleosides
Drug Categories	nucleic acids, nucleotides, and nucleosides
Drug Categories	heterocyclic compounds, 1-ring
Drug Categories	heterocyclic compounds
Drug Categories	glycosides
Drug Categories	carbohydrates
Drug Groups	experimental
Drug Type	small molecule
Drug Categories	pyrimidine analog
Drug Categories	analogs/derivatives
Drug Groups	investigational

(1 More Sources)

Publications:

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos
Lang et al., 2001, Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells., Mol. Pharmacol.
Loewen et al., 1999, Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2., J. Biol. Chem.
Hammond, 2000, Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity., Naunyn Schmiedebergs Arch. Pharmacol.
Iwamoto et al., 1981, Insulin action in cultured HTC and H35 rat hepatoma cells: receptor binding and hormone sensitivity., Endocrinology
Hawkins et al., 1997, The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake., J. Biol. Chem.
Bouchie et al., 2000, P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

URIDINE SLC28A3

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

URIDINE SLC28A2

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Lang et al., 2001, Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells., Mol. Pharmacol.

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

URIDINE SLC28A1

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Loewen et al., 1999, Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2., J. Biol. Chem.

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

URIDINE SLC29A1

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Hammond, 2000, Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity., Naunyn Schmiedebergs Arch. Pharmacol.

URIDINE TAT

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Iwamoto et al., 1981, Insulin action in cultured HTC and H35 rat hepatoma cells: receptor binding and hormone sensitivity., Endocrinology
URIDINE SLC2A4

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Hawkins et al., 1997, The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake., J. Biol. Chem.
URIDINE SERPINE1

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Bouchie et al., 2000, P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.

URIDINE LSM6

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

URIDINE TYMP

Interaction Types & Directionality:

n/a

Interaction Info:

Publications:

DrugBank: DB02745

Version: 5.1.7

Alternate Names:

URIDINE DrugBank Drug Name

58-96-8 CAS Number

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups investigational

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

DTC: URIDINE

Version: 02-September-2020

Alternate Names:

CHEMBL100259 ChEMBL Drug ID

Drug Info:

Publications:

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

NCI: URIDINE

Version: 14-September-2017

Alternate Names:

C922 NCI drug code

Drug Info:

Publications:

Bouchie et al., 2000, P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.

Lang et al., 2001, Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells., Mol. Pharmacol.

Loewen et al., 1999, Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2., J. Biol. Chem.

TTD: Uridine
- Version: 2020.06.01
Alternate Names:

D0Y7DP TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL100259
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

URIDINE Drug Record

URIDINE chembl:CHEMBL100259

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Hammond, 2000, Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity., Naunyn Schmiedebergs Arch. Pharmacol.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Iwamoto et al., 1981, Insulin action in cultured HTC and H35 rat hepatoma cells: receptor binding and hormone sensitivity., Endocrinology

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Hawkins et al., 1997, The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake., J. Biol. Chem.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Bouchie et al., 2000, P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.

Interaction Types & Directionality: n/a

Interaction Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Interaction Types & Directionality: n/a

Interaction Info:

Publications:

DrugBank: DB02745

Alternate Names: URIDINE DrugBank Drug Name 58-96-8 CAS Number

Drug Info: Drug Type small molecule Drug Groups experimental Drug Groups investigational

Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

DTC: URIDINE

Alternate Names: CHEMBL100259 ChEMBL Drug ID

Drug Info:

Publications: Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

NCI: URIDINE

Alternate Names: C922 NCI drug code

Drug Info:

TTD: Uridine

Alternate Names: D0Y7DP TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL100259

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

Publications:

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

Interaction Types & Directionality:

n/a

Interaction Types & Directionality:

n/a

Interaction Types & Directionality:

n/a

Publications:

Hammond, 2000, Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity., Naunyn Schmiedebergs Arch. Pharmacol.

Interaction Types & Directionality:

n/a

Publications:

Iwamoto et al., 1981, Insulin action in cultured HTC and H35 rat hepatoma cells: receptor binding and hormone sensitivity., Endocrinology

Interaction Types & Directionality:

n/a

Publications:

Hawkins et al., 1997, The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake., J. Biol. Chem.

Interaction Types & Directionality:

n/a

Publications:

Bouchie et al., 2000, P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells., Arterioscler. Thromb. Vasc. Biol.

Interaction Types & Directionality:

n/a

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Interaction Types & Directionality:

n/a

Alternate Names:

URIDINE DrugBank Drug Name

58-96-8 CAS Number

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups investigational

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

CHEMBL100259 ChEMBL Drug ID

Publications:

Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

Alternate Names:

C922 NCI drug code

Alternate Names:

D0Y7DP TTD Drug ID