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THYROTROPIN Drug Record

  • Summary
  • Interactions
  • Claims
  • THYROTROPIN chembl:CHEMBL1201532 Approved

    Alternate Names:

    THYTROPAR
    THYROTROPIN
    THYROTROPHIN

    Drug Info:

    (0 More Sources)

    Publications:

    Hill et al., 1994, Basic fibroblast growth factor (basic FGF) in isolated ovine thyroid follicles: thyrotropin stimulation and effects of basic FGF on DNA synthesis, iodine uptake and organification, and the release of insulin-like growth factors (IGFs) and IGF-binding proteins., Thyroid
    de Moura et al., 2001, Aging and gender affect the response of thyrotropin (TSH) to gastrin releasing peptide (GRP) in rats., Life Sci.
    Moura et al., 1999, Interaction between substance P and gastrin-releasing peptide on thyrotropin secretion by rat pituitary in vitro., Braz. J. Med. Biol. Res.
    Colletta et al., 1986, Induction of the c-fos oncogene by thyrotropic hormone in rat thyroid cells in culture., Science
    Heldin et al., 1988, Epidermal growth factor, but not thyrotropin, stimulates the expression of c-fos and c-myc messenger ribonucleic acid in porcine thyroid follicle cells in primary culture., Endocrinology
    Morishige et al., 1999, Secretagogue-induced exocytosis recruits G protein-gated K+ channels to plasma membrane in endocrine cells., J. Biol. Chem.
  • THYROTROPIN   KCNJ3

    Interaction Score: 8.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10075694


    Sources:
    NCI

  • THYROTROPIN   GRP

    Interaction Score: 5.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11292067 10464393


    Sources:
    NCI

  • THYROTROPIN   FGF2

    Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7519916


    Sources:
    NCI

  • THYROTROPIN   MYC

    Interaction Score: 0.93

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3726540 3125035


    Sources:
    NCI

  • THYROTROPIN   TSHR

    Interaction Score: 0.27

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Thyroid stimulating hormone receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • NCI: THYROTROPIN

    • Version: 14-September-2017

    Alternate Names:
    C887 NCI drug code

    Drug Info:

    Publications:
    Hill et al., 1994, Basic fibroblast growth factor (basic FGF) in isolated ovine thyroid follicles: thyrotropin stimulation and effects of basic FGF on DNA synthesis, iodine uptake and organification, and the release of insulin-like growth factors (IGFs) and IGF-binding proteins., Thyroid
    Heldin et al., 1988, Epidermal growth factor, but not thyrotropin, stimulates the expression of c-fos and c-myc messenger ribonucleic acid in porcine thyroid follicle cells in primary culture., Endocrinology
    Colletta et al., 1986, Induction of the c-fos oncogene by thyrotropic hormone in rat thyroid cells in culture., Science

  • TTD: Thyrotropin

    • Version: 2020.06.01

    Alternate Names:
    D03EER TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1201532

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL1201532

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21