NGX-424 |
LY-293558 |
LY-293,558 |
FDA Approval | not approved |
Drug Class | small molecule |
Drug Indications | antimigraine agent,analgesic |
Drug Type | small molecule |
Drug Groups | investigational |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Categories | receptors, ampa, antagonists & inhibitors |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
Trial Name | tezampanel, NGX424,NGX426 |
antagonist (inhibitory) |
Novel drug target | Novel Target |
Trial Name | tezampanel, NGX424,NGX426 |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
Direct Interaction | yes |
Trial Name | tezampanel, NGX424,NGX426 |
n/a |
Trial Name | tezampanel, NGX424,NGX426 |
Novel drug target | Novel Target |
antagonist (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
antagonist (inhibitory) |
Trial Name | tezampanel, NGX424,NGX426 |
Novel drug target | Established target |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
antagonist (inhibitory) |
Trial Name | tezampanel, NGX424,NGX426 |
Novel drug target | Established target |
Specific Action of the Ligand | Antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
Direct Interaction | yes |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | tezampanel, NGX424,NGX426 |
Novel drug target | Established target |
Direct Interaction | yes |
TEZAMPANEL | DrugBank Drug Name |
154652-83-2 | CAS Number |
CHEMBL14935 | ChEMBL ID |
Drug Type | small molecule |
Drug Groups | investigational |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Indications | antimigraine agent,analgesic |
Drug Class | small molecule |
FDA Approval | not approved |
TEZAMPANEL | GuideToPharmacology Ligand Name |