DGIdb - TETRACAINE Drug Record

TETRACAINE chembl:CHEMBL698 Approved

Alternate Names:

AMETHOCAINE
DICAINE
TETRACAINE
AMETOP
METRASPRAY
MEDIHALER-TETRACAINE
PONTOCAINE
2-(DIMETHYLAMINO)ETHYL 4-(BUTYLAMINO)BENZOATE
P-(BUTYLAMINO)BENZOIC ACID Β-(DIMETHYLAMINO)ETHYL ESTER
P-BUTYLAMINOBENZOYL-2-DIMETHYLAMINOETHANOL
TETRACAINE HCL
P-(BUTYLAMINO)BENZOIC ACID BETA-(DIMETHYLAMINO)ETHYL ESTER
TETRACAÍNA
AMETHOCAINE HCL
2-(DIMETHYLAMINO)ETHYL P-(BUTYLAMINO)BENZOATE
TET150
TÉTRACAÏNE
DIÄTHYLAMINOÄTHANOL ESTER DER P-BUTYLAMINOBENZÖSÄURE
rxcui:10391
chemidplus:94-24-6
chembl:CHEMBL698
pubchem.compound:5411
drugbank:09085

Drug Info:

(0 More Sources)

Publications:

Fozzard HA et al., 2011, The sodium channel as a target for local anesthetic drugs., Front Pharmacol
Gammaitoni AR et al., 2013, Heated lidocaine/tetracaine patch for treatment of patellar tendinopathy pain., J Pain Res

TETRACAINE SCN1A

Interaction Score: 0.28

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
22053156 23888118

Sources:
ChemblInteractions
TETRACAINE SCN10A

Interaction Score: 0.15

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
None found

Sources:
ChemblInteractions TTD
TETRACAINE SCN7A

Interaction Score: 0.11

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN8A

Interaction Score: 0.1

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN11A

Interaction Score: 0.1

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN3A

Interaction Score: 0.1

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN2A

Interaction Score: 0.1

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN4A

Interaction Score: 0.09

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE SCN9A

Interaction Score: 0.09

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
TETRACAINE G6PD

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

Combination therapy Lidocaine,Tetracaine

Combination therapy Oxymetazoline,Tetracaine

PMIDs:
None found

Sources:
FDA
TETRACAINE SCN5A

Interaction Score: 0.07

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

TTD: Tetracaine
- Version: 2020.06.01
Alternate Names:

D08HQK TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL698
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL698
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
FDA: Tetracaine
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:

Direct Interaction	yes
Mechanism of Interaction	Sodium channel alpha subunit blocker

Combination therapy	Lidocaine,Tetracaine
Combination therapy	Oxymetazoline,Tetracaine

TETRACAINE Drug Record

TETRACAINE chembl:CHEMBL698 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs: 22053156 23888118

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs: None found

Sources: ChemblInteractions TTD

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info: Combination therapy Lidocaine,Tetracaine Combination therapy Oxymetazoline,Tetracaine

PMIDs: None found

Sources: FDA

Interaction Types & Directionality: blocker (inhibitory)

Interaction Info: Mechanism of Interaction Sodium channel alpha subunit blocker Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

TTD: Tetracaine

Alternate Names: D08HQK TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL698

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL698

Alternate Names:

Drug Info:

Publications:

FDA: Tetracaine

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
22053156 23888118

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
None found

Sources:
ChemblInteractions TTD

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Sodium channel alpha subunit blocker

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Combination therapy Lidocaine,Tetracaine

Combination therapy Oxymetazoline,Tetracaine

PMIDs:
None found

Sources:
FDA

Interaction Types & Directionality:

blocker (inhibitory)

Interaction Info:

Mechanism of Interaction Sodium channel alpha subunit blocker

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Alternate Names:

D08HQK TTD Drug ID