DGIdb - TARIQUIDAR Drug Record

TARIQUIDAR chembl:CHEMBL348475

Alternate Names:

TARIQUIDAR
XR-9576

Drug Info:

FDA Approval	not approved
Drug Class	small molecule
Drug Indications	adjuvant to chemotherapy
Drug Type	small molecule
Drug Groups	investigational
Drug Categories	drug resistance, multiple
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	p-glycoprotein inhibitors

(2 More Sources)

Publications:

Bauer F et al., 2010, Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor., Bioorg Med Chem
Goldsborough AS et al., 2011, Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin., J Med Chem

TARIQUIDAR ABCG2

Interaction Score: 0.89

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20621487

Sources:
DTC
TARIQUIDAR ABCB1

Interaction Score: 0.67

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction P-glycoprotein 1 inhibitor

Direct Interaction yes

Trial Name tariquidar

PMIDs:
21657271

Sources:
DTC DrugBank TdgClinicalTrial ChemblInteractions PharmGKB

DrugBank: DB06240
- Version: 5.1.7
Alternate Names:

TARIQUIDAR DrugBank Drug Name

206873-63-4 CAS Number

CHEMBL348475 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups investigational

Drug Categories drug resistance, multiple

Publications:
TdgClinicalTrial: TARIQUIDAR
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications adjuvant to chemotherapy

Drug Class small molecule

FDA Approval not approved

Publications:

DTC: TARIQUIDAR

Version: 02-September-2020

Alternate Names:

CHEMBL348475 ChEMBL Drug ID

Drug Info:

Publications:

Bauer F et al., 2010, Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor., Bioorg Med Chem

Goldsborough AS et al., 2011, Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin., J Med Chem

ChemblInteractions: CHEMBL348475
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL348475
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: Tariquidar
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Mechanism of Interaction	P-glycoprotein 1 inhibitor
Direct Interaction	yes
Trial Name	tariquidar

TARIQUIDAR	DrugBank Drug Name
206873-63-4	CAS Number
CHEMBL348475	ChEMBL ID

TARIQUIDAR Drug Record

TARIQUIDAR chembl:CHEMBL348475

Alternate Names:

Drug Info:

Publications:

TARIQUIDAR ABCG2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20621487

Sources: DTC

TARIQUIDAR ABCB1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction P-glycoprotein 1 inhibitor Direct Interaction yes Trial Name tariquidar

PMIDs: 21657271

Sources: DTC DrugBank TdgClinicalTrial ChemblInteractions PharmGKB

DrugBank: DB06240

Alternate Names: TARIQUIDAR DrugBank Drug Name 206873-63-4 CAS Number CHEMBL348475 ChEMBL ID

Drug Info: Drug Type small molecule Drug Groups investigational Drug Categories drug resistance, multiple

Publications:

TdgClinicalTrial: TARIQUIDAR

Alternate Names:

Drug Info: Drug Indications adjuvant to chemotherapy Drug Class small molecule FDA Approval not approved

Publications:

DTC: TARIQUIDAR

Alternate Names: CHEMBL348475 ChEMBL Drug ID

Drug Info:

ChemblInteractions: CHEMBL348475

Alternate Names:

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL348475

Alternate Names:

Drug Info:

Publications:

PharmGKB: Tariquidar

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
20621487

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction P-glycoprotein 1 inhibitor

Direct Interaction yes

Trial Name tariquidar

PMIDs:
21657271

Sources:
DTC DrugBank TdgClinicalTrial ChemblInteractions PharmGKB

Alternate Names:

TARIQUIDAR DrugBank Drug Name

206873-63-4 CAS Number

CHEMBL348475 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups investigational

Drug Categories drug resistance, multiple

Drug Info:

Drug Indications adjuvant to chemotherapy

Drug Class small molecule

FDA Approval not approved

Alternate Names:

CHEMBL348475 ChEMBL Drug ID