• Interaction Score: 1.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type uveal melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    22515704


    Sources:
    JAX-CKB

  • Interaction Score: 1.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type uveal melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    22515704


    Sources:
    JAX-CKB

  • Interaction Score: 0.66

    Interaction Types & Directionality:
    inhibitor (inhibitory)
    allosteric modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
    Reported Cancer Type Melanoma

  • Interaction Score: 0.5

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
    Direct Interaction yes

  • Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type predicted – sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    26439693


    Sources:
    JAX-CKB

  • Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type melanoma
    Response Type sensitive
    Approval Status Phase I


    Sources:
    JAX-CKB

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type cholangiocarcinoma
    Response Type sensitive
    Approval Status Preclinical - Pdx

    PMIDs:
    26439693


    Sources:
    JAX-CKB

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type colorectal cancer
    Response Type predicted – sensitive
    Approval Status Preclinical - Pdx & cell culture

    PMIDs:
    26439693


    Sources:
    JAX-CKB