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RESVERATROL Drug Record

  • Summary
  • Interactions
  • Claims
  • RESVERATROL chembl:CHEMBL165 Antineoplastic

    Alternate Names:

    BIA 6-512
    (E)-RESVERATROL
    NSC-327430
    RESVERATROL
    BIA-6-512
    3,5,4'-TRIHYDROXY-TRANS-STILBENE

    Drug Info:

    Drug Indications antidiabetic,antineoplastic agent
    FDA Approval not approved
    Drug Class small molecule
    Drug Indications for treatment of herpes simplex virus 1
    Drug Categories ribonucleotide reductases, antagonists & inhibitors
    Drug Categories antioxidants
    Drug Categories antimutagenic agents
    Drug Categories antiplatelet agents
    Drug Categories benzopyrans
    Drug Categories chromones
    Drug Categories compounds used in a research, industrial, or household setting
    Drug Categories cytochrome p-450 cyp1a2 inhibitors (strength unknown)
    Drug Categories cytochrome p-450 cyp3a4 inhibitors
    Drug Categories cytochrome p-450 cyp3a4 inhibitors (strength unknown)
    Drug Categories cytochrome p-450 enzyme inhibitors
    Drug Categories cytochrome p-450 substrates
    Drug Categories flavones
    Drug Categories flavonoids
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories polyphenols
    Drug Categories pyrans
    Drug Categories stilbenes
    Drug Categories vasodilating agents
    (2 More Sources)

    Publications:

    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Buryanovskyy et al., 2004, Crystal structure of quinone reductase 2 in complex with resveratrol., Biochemistry
    Wang et al., 2004, Identification and purification of resveratrol targeting proteins using immobilized resveratrol affinity chromatography., Biochem. Biophys. Res. Commun.
    Wu J et al., 2013, Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate., J Med Chem
    Ota H et al., 2013, trans-Resveratrol in Gnetum gnemon protects against oxidative-stress-induced endothelial senescence., J Nat Prod
    Milne et al., 2007, Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes., Nature
    Lakshminarasimhan M et al., 2013, Sirt1 activation by resveratrol is substrate sequence-selective., Aging (Albany NY)
    Hubbard BP et al., 2013, Evidence for a common mechanism of SIRT1 regulation by allosteric activators., Science
    Su JL et al., 2007, Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol., J Biol Chem
    Ma et al., 2005, Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis., Inflamm. Res.
    Youn et al., 2005, Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex., J. Immunol.
    Miura et al., 2004, Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property., Clin. Exp. Metastasis
    Boissy et al., 2005, Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation., Cancer Res.
    Park JB, 2001, Inhibition of glucose and dehydroascorbic acid uptakes by resveratrol in human transformed myelocytic cells., J Nat Prod
    Stewart et al., 2000, Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation., Biochem. Pharmacol.
    Aziz et al., 2005, Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?, FASEB J.
    Aziz et al., Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin., Photochem. Photobiol.
    Baek et al., 2002, Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53., Carcinogenesis
    Sbarra et al., 2005, In vitro polyphenol effects on activity, expression and secretion of pancreatic bile salt-dependent lipase., Biochim. Biophys. Acta
    Mollerup et al., 2001, Lung carcinogenesis: resveratrol modulates the expression of genes involved in the metabolism of PAH in human bronchial epithelial cells., Int. J. Cancer
    Lu C et al., 2013, Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease., J Med Chem
    Ahn JS et al., 2007, Novel method for quantitative determination of amyloid fibrils of alpha-synuclein and amyloid beta/A4 protein by using resveratrol., Anal Biochem
    Poolman et al., 2005, Inhibition of the respiratory burst by resveratrol in human monocytes: correlation with inhibition of PI3K signaling., Free Radic. Biol. Med.
    Gagliano et al., 2005, Effect of resveratrol on matrix metalloproteinase-2 (MMP-2) and Secreted Protein Acidic and Rich in Cysteine (SPARC) on human cultured glioblastoma cells., Biomed. Pharmacother.
    Tseng et al., 2004, Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats., Clin. Cancer Res.
    Reagan-Shaw et al., 2004, Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin., Oncogene
    Konno H et al., 2013, Melinjo (Gnetum gnemon L.) Seed Extract Decreases Serum Uric Acid Levels in Nonobese Japanese Males: A Randomized Controlled Study., Evid Based Complement Alternat Med
    Hsieh TC et al., 2014, Biochemical and cellular evidence demonstrating AKT-1 as a binding partner for resveratrol targeting protein NQO2., PLoS One
    Lekli et al., 2008, Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin., Am. J. Physiol. Heart Circ. Physiol.
    Lappano R et al., 2009, Structure-activity relationships of resveratrol and derivatives in breast cancer cells., Mol Nutr Food Res
    Bezstarosti et al., Differential proteomic profiling to study the mechanism of cardiac pharmacological preconditioning by resveratrol., J. Cell. Mol. Med.
    Wang et al., 2006, Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts., Biochem. Biophys. Res. Commun.
    Sakoguchi-Okada et al., 2007, Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells., Biochem. Pharmacol.
    Fulda et al., 2004, Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol., Cancer Res.
    de Medina P et al., 2005, Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators., J Med Chem
    Das et al., 2006, Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1/cAMP response element-binding protein signaling., J. Pharmacol. Exp. Ther.
    Das J et al., 2011, Chemical modifications of resveratrol for improved protein kinase C alpha activity., Bioorg Med Chem
    Bollmann F et al., 2014, Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity., Nucleic Acids Res
    Davis PJ et al., 2013, Small molecule hormone or hormone-like ligands of integrin αVβ3: implications for cancer cell behavior., Horm Cancer
    Ferry G et al., 2010, Old and new inhibitors of quinone reductase 2., Chem Biol Interact
    Salas M et al., 2013, Resolution of the direct interaction with and inhibition of the human GLUT1 hexose transporter by resveratrol from its effect on glucose accumulation., Am J Physiol Cell Physiol
    MacCarrone M et al., 1999, Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity., Eur J Biochem
    Dring AM et al., 2010, Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands., Chem Biol Interact
    Sajish M et al., 2015, A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol., Nature
    Srivastava R et al., 2005, Resveratrol inhibits type II phosphatidylinositol 4-kinase: a key component in pathways of phosphoinositide turn over., Biochem Pharmacol
    Ito Y et al., 2013, Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4'-amino-3,5-dihydroxy-trans-stilbene., J Nutr Sci Vitaminol (Tokyo)
    Wang Y et al., 2010, Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines., Hum Mol Genet
  • RESVERATROL   CLEC14A

    Interaction Score: 1.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20729295


    Sources:
    DrugBank

  • RESVERATROL   PECAM1

    Interaction Score: 1.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15041740


    Sources:
    NCI

  • RESVERATROL   PI4K2B

    Interaction Score: 0.85

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16102733


    Sources:
    DrugBank

  • RESVERATROL   FOXO3

    Interaction Score: 0.85

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17513867


    Sources:
    DTC

  • RESVERATROL   YARS

    Interaction Score: 0.57

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    25533949


    Sources:
    DrugBank

  • RESVERATROL   KHSRP

    Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25352548


    Sources:
    DrugBank

  • RESVERATROL   SLC2A3

    Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11277764


    Sources:
    DTC

  • RESVERATROL   DIABLO

    Interaction Score: 0.51

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15837718 15469386


    Sources:
    NCI

  • RESVERATROL   RIPK1

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16116226


    Sources:
    NCI

  • RESVERATROL   CEL

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16099206


    Sources:
    NCI

  • RESVERATROL   GDF15

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11895857


    Sources:
    NCI

  • RESVERATROL   HSPB2

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17125593 16759640


    Sources:
    NCI

  • RESVERATROL   MTNR1B

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20399199


    Sources:
    DrugBank

  • RESVERATROL   SIRT1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23316803 23859249 18046409 23524286 23471411


    Sources:
    DTC DrugBank

  • RESVERATROL   ITGA5

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23943159


    Sources:
    DrugBank

  • RESVERATROL   MTNR1A

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20399199


    Sources:
    DrugBank

  • RESVERATROL   CBR1

    Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    24064738


    Sources:
    DrugBank

  • RESVERATROL   PRKD1

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11008129


    Sources:
    NCI

  • RESVERATROL   SLC2A1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23615963


    Sources:
    DrugBank

  • RESVERATROL   NQO2

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15350128 15381063


    Sources:
    DrugBank

  • RESVERATROL   HGF

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15672869


    Sources:
    NCI

  • RESVERATROL   ITGB3

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23943159


    Sources:
    DrugBank

  • RESVERATROL   BIRC5

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17270149 15837718 14729643


    Sources:
    NCI

  • RESVERATROL   APP

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23799643 17597573


    Sources:
    DTC DrugBank

  • RESVERATROL   NR1I3

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20869355


    Sources:
    DrugBank

  • RESVERATROL   BGLAP

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16267019


    Sources:
    NCI

  • RESVERATROL   PRKCA

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21880495


    Sources:
    DTC

  • RESVERATROL   MMP2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16084059


    Sources:
    NCI

  • RESVERATROL   SNCA

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17597573


    Sources:
    DrugBank

  • RESVERATROL   ALOX5

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10491155


    Sources:
    DrugBank

  • RESVERATROL   AKT1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    17513867 24968355


    Sources:
    DTC DrugBank

  • RESVERATROL   SLC2A4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18065527


    Sources:
    NCI

  • RESVERATROL   CSNK2A1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    DrugBank

  • RESVERATROL   IL1B

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16389574


    Sources:
    NCI

  • RESVERATROL   AHR

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15634023


    Sources:
    DTC DrugBank

  • RESVERATROL   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11279601


    Sources:
    NCI

  • RESVERATROL   PTGS2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    11752352


    Sources:
    DrugBank GuideToPharmacology

  • RESVERATROL   PDE4D

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Resveratrol
    Novel drug target Established target
    Trial Name SRT501

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • RESVERATROL   GFER

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   PDE4B

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name SRT501
    Novel drug target Established target
    Trial Name Resveratrol

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • RESVERATROL   PPARA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24454499


    Sources:
    DrugBank

  • RESVERATROL   NFKB2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   RELA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   PTGS1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    DrugBank

  • RESVERATROL   MAPK14

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16525036


    Sources:
    NCI

  • RESVERATROL   PPARG

    Interaction Score: 0.01

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    24454499


    Sources:
    DrugBank GuideToPharmacology

  • RESVERATROL   NR1I2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20869355


    Sources:
    DrugBank

  • RESVERATROL   ALOX15

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10491155


    Sources:
    DrugBank

  • RESVERATROL   PIK3CA

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15925284


    Sources:
    NCI

  • RESVERATROL   CDK2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15122319


    Sources:
    NCI

  • RESVERATROL   ESR1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19496085


    Sources:
    DTC DrugBank

  • RESVERATROL   NFKB1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   BRCA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   SMN2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   SMN1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   NPC1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   HIF1A

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   HTT

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   POLK

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   ATAD5

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   TP53

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   HSD17B10

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   MAPT

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   NFE2L2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   EHMT2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   AR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RESVERATROL   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB02709

    • Version: 5.1.7

    Alternate Names:
    RESVERATROL DrugBank Drug Name
    501-36-0 CAS Number
    Co-Balamin Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups investigational
    Drug Categories analgesics

    Publications:
    Bollmann F et al., 2014, Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity., Nucleic Acids Res
    Davis PJ et al., 2013, Small molecule hormone or hormone-like ligands of integrin αVβ3: implications for cancer cell behavior., Horm Cancer
    Konno H et al., 2013, Melinjo (Gnetum gnemon L.) Seed Extract Decreases Serum Uric Acid Levels in Nonobese Japanese Males: A Randomized Controlled Study., Evid Based Complement Alternat Med

  • TdgClinicalTrial: RESVERATROL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of herpes simplex virus 1
    Drug Class small molecule
    FDA Approval not approved

    Publications:

  • NCI: RESVERATROL

    • Version: 14-September-2017

    Alternate Names:
    C1215 NCI drug code

    Drug Info:

    Publications:
    Ma et al., 2005, Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis., Inflamm. Res.
    Youn et al., 2005, Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex., J. Immunol.
    Miura et al., 2004, Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property., Clin. Exp. Metastasis

  • DTC: RESVERATROL

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL165 ChEMBL Drug ID

    Drug Info:

    Publications:
    Su JL et al., 2007, Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol., J Biol Chem
    Das J et al., 2011, Chemical modifications of resveratrol for improved protein kinase C alpha activity., Bioorg Med Chem
    Wu J et al., 2013, Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate., J Med Chem

  • GuideToPharmacology: 252827399

    • Version: 29-September-2020

    Alternate Names:
    RESVERATROL GuideToPharmacology Ligand Name

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL165

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21