• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

QUERCETIN Drug Record

  • Summary
  • Interactions
  • Claims
  • QUERCETIN chembl:CHEMBL50 Antineoplastic

    Alternate Names:

    NSC 57655
    NSC 9219
    SOPHORETIN
    NSC-57655
    LDN 0052529
    NSC-9219
    MELETIN
    XANTHAURINE
    LDN-0052529
    C.I. NATURAL RED 1
    QUERCETIN

    Drug Info:

    Drug Categories flavonols
    Drug Categories flavonoids
    Drug Categories chromones
    Drug Class Kinase Inhibitors
    Drug Groups investigational
    Drug Categories compounds used in a research, industrial, or household setting
    Drug Categories comt inhibitors
    Drug Categories comt substrates
    Drug Categories cytochrome p-450 cyp2c8 inhibitors (strength unknown)
    Drug Categories cytochrome p-450 enzyme inhibitors
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories oatp1b1/slco1b1 inhibitors
    Drug Categories p-glycoprotein inhibitors
    (2 More Sources)

    Publications:

    Wang RE et al., 2009, Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives., J Med Chem
    Tanigawa et al., 2007, Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin., Free Radic. Biol. Med.
    Angeloni et al., 2007, Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress., Biochimie
    Amrutha K et al., 2014, Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study., Bioorg Med Chem Lett
    Lee et al., 2006, Quercetin arrests G2/M phase and induces caspase-dependent cell death in U937 cells., Cancer Lett.
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Sabbah DA et al., 2012, Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases., Bioorg Med Chem Lett
    Kim et al., 2005, Quercetin decreases the expression of ErbB2 and ErbB3 proteins in HT-29 human colon cancer cells., J. Nutr. Biochem.
    Lam et al., 2005, Fourier transform infrared spectroscopy evaluation of low density lipoprotein oxidation in the presence of quercetin, catechin, and alpha-tocopherol., Lipids
    Aligiannis et al., 2001, Flavonoids as cycline-dependent kinase inhibitors: inhibition of cdc 25 phosphatase activity by flavonoids belonging to the quercetin and kaempferol series., Planta Med.
    Kurata et al., 1992, Effects of phenol compounds, glutathione analogues and a diuretic drug on glutathione S-transferase, glutathione reductase and glutathione peroxidase from canine erythrocytes., Comp. Biochem. Physiol., B
    Ciolino et al., 1999, Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially., Biochem. J.
    Vasquez-Martinez Y et al., 2007, Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2., Bioorg Med Chem
    Ueno et al., 1984, Interaction between quercetin and superoxide radicals. Reduction of the quercetin mutagenicity., J. Pharmacobio-dyn.
    Nazir N et al., 2011, Evaluation of antioxidant and antimicrobial activities of Bergenin and its derivatives obtained by chemoenzymatic synthesis., Eur J Med Chem
    Sassano MF et al., 2013, Colloidal aggregation causes inhibition of G protein-coupled receptors., J Med Chem
    Fiorelli et al., 1999, Estrogen synthesis in human colon cancer epithelial cells., J. Steroid Biochem. Mol. Biol.
    Zahir A et al., 1996, DNA topoisomerase I inhibitors: cytotoxic flavones from Lethedon tannaensis., J Nat Prod
    Larocca et al., 1991, Antiproliferative activity of quercetin on normal bone marrow and leukaemic progenitors., Br. J. Haematol.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Aquino et al., 1998, The constitutive heat shock protein-70 is required for optimal expression of myelin basic protein during differentiation of oligodendrocytes., Neurochem. Res.
    Deora et al., Down-modulation of P210bcr/abl induces apoptosis/differentiation in K562 leukemic blast cells., Tumori
    Constantinou A et al., 1995, Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships., J Nat Prod
    Atrahimovich D et al., 2013, The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study., Bioorg Med Chem
    van der Woude H et al., 2005, The stimulation of cell proliferation by quercetin is mediated by the estrogen receptor., Mol Nutr Food Res
    Leung LK et al., 2004, Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction., Br J Nutr
    Maggiolini M et al., 2001, Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells., Mol Pharmacol
    Kuiper GG et al., 1998, Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta., Endocrinology
    Lau AJ et al., 2015, 3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease., Pharmacol Res
    Shimizu M et al., 2015, Quercetin represses apolipoprotein B expression by inhibiting the transcriptional activity of C/EBPβ., PLoS One
    Flaveny CA et al., 2009, Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice., Mol Pharmacol
    Wang RE et al., 2011, Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins., Bioorg Med Chem
    Hintzpeter J et al., 2015, Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1., Chem Biol Interact
    Buryanovskyy et al., 2004, Crystal structure of quinone reductase 2 in complex with resveratrol., Biochemistry
    Shimada T et al., 2010, Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives., Chem Res Toxicol
    Hong H et al., 2015, Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein., Toxicol Sci
  • QUERCETIN   RUVBL2

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   HSPA2

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   EIF3F

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   CEBPB

    Interaction Score: 1.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    25875015


    Sources:
    DrugBank

  • QUERCETIN   HIBCH

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   CSNK2B

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   STK17B

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   UGT3A1

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   ATP5C1

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   UBA1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   SF3B3

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   ATP5A1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   ATP5B

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   GABPA

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17462537


    Sources:
    NCI

  • QUERCETIN   HSF1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19296652


    Sources:
    DTC

  • QUERCETIN   ACTB

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   CD34

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1772777


    Sources:
    NCI

  • QUERCETIN   PKN3

    Interaction Score: 0.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   CDC25C

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11488465


    Sources:
    NCI

  • QUERCETIN   MBP

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9482255


    Sources:
    NCI

  • QUERCETIN   PKN1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   CBR1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25541467


    Sources:
    DrugBank

  • QUERCETIN   PON1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23623675


    Sources:
    DTC

  • QUERCETIN   HCK

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • QUERCETIN   XDH

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6099408 21474216


    Sources:
    NCI DTC

  • QUERCETIN   E2F1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16274926


    Sources:
    NCI

  • QUERCETIN   APOB

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16149735


    Sources:
    NCI

  • QUERCETIN   PRKCH

    Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKD1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   GSR

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1478066


    Sources:
    NCI

  • QUERCETIN   PRKCZ

    Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKCI

    Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   GALK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   NQO2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    15350128


    Sources:
    DrugBank

  • QUERCETIN   CYP1A1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10359656


    Sources:
    NCI

  • QUERCETIN   AVPR2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23437772


    Sources:
    DTC

  • QUERCETIN   SHBG

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25349334


    Sources:
    DrugBank

  • QUERCETIN   PIK3C2A

    Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3R6

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3R4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3C2B

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKCE

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   HSPB1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19296652


    Sources:
    DTC

  • QUERCETIN   CYP1B1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21053930


    Sources:
    DrugBank

  • QUERCETIN   PIK3C3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   GPR35

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   PIK3C2G

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   CYP19A1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10704911


    Sources:
    NCI

  • QUERCETIN   PRKCQ

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   ESR2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15937998 15182386 11502892 9751507


    Sources:
    DrugBank

  • QUERCETIN   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKCB

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   CSNK2A1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   PIK3CB

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    17045724


    Sources:
    NCI MyCancerGenome

  • QUERCETIN   MAPK3

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17045724


    Sources:
    NCI

  • QUERCETIN   PIM1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • QUERCETIN   BAX

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15741050


    Sources:
    NCI

  • QUERCETIN   NFKB2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25190466


    Sources:
    DTC

  • QUERCETIN   PRKCG

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   RELA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25190466


    Sources:
    DTC

  • QUERCETIN   PRKCA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3CA

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    22212721 17045724


    Sources:
    NCI DTC MyCancerGenome

  • QUERCETIN   PIK3R5

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   TOP2A

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8759170 7769390


    Sources:
    DTC

  • QUERCETIN   PRKD2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3R3

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3R1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKCD

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3R2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PRKD3

    Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   PIK3CG

    Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank MyCancerGenome

  • QUERCETIN   AHR

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19299563


    Sources:
    DrugBank

  • QUERCETIN   ABL1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9349317


    Sources:
    NCI

  • QUERCETIN   NFKB1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25190466


    Sources:
    DTC

  • QUERCETIN   ESR1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15937998 15182386 11502892 9751507


    Sources:
    DrugBank

  • QUERCETIN   TOP1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8759170


    Sources:
    DTC

  • QUERCETIN   ALOX15B

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   PIK3CD

    Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • QUERCETIN   NR1I2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:

    PMIDs:
    26238175


    Sources:
    DrugBank

  • QUERCETIN   ALOX15

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17869117


    Sources:
    DTC

  • QUERCETIN   F2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • QUERCETIN   BLM

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   MPHOSPH8

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   HIF1A

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   POLH

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   RECQL

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   APEX1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   POLB

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   DRD1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   FEN1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   YES1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   POLI

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   HPGD

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   POLK

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   KDM4E

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   ATAD5

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   ALDH1A1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   HSD17B10

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   CYP2C9

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   MAPT

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   CYP2C19

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   CYP1A2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   EHMT2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB04216

    • Version: 5.1.7

    Alternate Names:
    QUERCETIN DrugBank Drug Name
    117-39-5 CAS Number
    CHEMBL50 ChEMBL ID

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Groups investigational

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    van der Woude H et al., 2005, The stimulation of cell proliferation by quercetin is mediated by the estrogen receptor., Mol Nutr Food Res
    Leung LK et al., 2004, Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction., Br J Nutr

  • MyCancerGenome: SOPHORETIN

    • Version: 20-Jun-2017

    Alternate Names:
    SOPHORETIN Generic Name
    QUERCETIN Generic Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

  • NCI: QUERCETIN

    • Version: 14-September-2017

    Alternate Names:
    C792 NCI drug code

    Drug Info:

    Publications:
    Tanigawa et al., 2007, Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin., Free Radic. Biol. Med.
    Ciolino et al., 1999, Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially., Biochem. J.
    Larocca et al., 1991, Antiproliferative activity of quercetin on normal bone marrow and leukaemic progenitors., Br. J. Haematol.

  • DTC: QUERCETIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL50 ChEMBL Drug ID

    Drug Info:

    Publications:
    Wang RE et al., 2009, Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives., J Med Chem
    Atrahimovich D et al., 2013, The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study., Bioorg Med Chem
    Zahir A et al., 1996, DNA topoisomerase I inhibitors: cytotoxic flavones from Lethedon tannaensis., J Nat Prod

  • TTD: Quercetin

    • Version: 2020.06.01

    Alternate Names:
    D0K8KX TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL50

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21