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PYRANTEL Drug Record

  • Summary
  • Interactions
  • Claims
  • PYRANTEL chembl:CHEMBL1626223 Approved

    Alternate Names:

    PYRANTEL
    PIRANTEL
    PYRANTELUM
    drugbank:11156
    chembl:CHEMBL1626223
    chemidplus:15686-83-6
    pubchem.compound:708857
    rxcui:8984

    Drug Info:

    Drug Type small molecule
    Drug Groups approved
    Drug Groups vet_approved
    Drug Categories anthelmintics
    Drug Categories anti-infective agents
    Drug Categories antinematodal agents
    Drug Categories antiparasitic agents
    Drug Categories antiparasitic products, insecticides and repellents
    Drug Categories central nervous system depressants
    Drug Categories drugs that are mainly renally excreted
    Drug Categories neuromuscular agents
    Drug Categories neuromuscular blocking agents
    Drug Categories neuromuscular depolarizing agents
    Drug Categories peripheral nervous system agents
    Drug Categories pyrimidines
    Drug Categories sulfur compounds
    Drug Categories tetrahydropyrimidine derivatives
    Drug Categories thiophenes
    (0 More Sources)

    Publications:

    Zhao P et al., 2010, Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity., Mol Pharmacol
    Rayes D et al., 2001, The anthelmintic pyrantel acts as a low efficacious agonist and an open-channel blocker of mammalian acetylcholine receptors., Neuropharmacology
  • PYRANTEL   GPR35

    Interaction Score: 3.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20826425


    Sources:
    DrugBank

  • PYRANTEL   CHRM1

    Interaction Score: 0.37

    Interaction Types & Directionality:
    agonist (activating)
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11489460


    Sources:
    DrugBank

  • DrugBank: DB11156

    • Version: 5.1.7

    Alternate Names:
    PYRANTEL DrugBank Drug Name
    15686-83-6 CAS Number
    CVS Pinworm Treatment Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups vet_approved

    Publications:
    Zhao P et al., 2010, Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity., Mol Pharmacol
    Rayes D et al., 2001, The anthelmintic pyrantel acts as a low efficacious agonist and an open-channel blocker of mammalian acetylcholine receptors., Neuropharmacology

  • ChemblDrugs: chembl:CHEMBL1626223

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2021-04-13