DGIdb - PUROMYCIN Drug Record

PUROMYCIN chembl:CHEMBL469912 Antineoplastic

Alternate Names:

CL-13900
P-638
3123L
TCMDC-123493
GNF-PF-2016
PUROMYCIN

Drug Info:

Drug Categories	cinnamates
Drug Categories	agents that produce neuromuscular block (indirect)
Drug Categories	aminoglycoside antibacterials
Drug Categories	anti-bacterial agents
Drug Categories	drugs that are mainly renally excreted
Drug Categories	drugs that are mainly renally excreted with narrow therapeutic index
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	narrow therapeutic index drugs
Drug Categories	nephrotoxic agents

(0 More Sources)

Publications:

Marvizon et al., 2003, Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord., Br. J. Pharmacol.
Mizokuchi et al., 1992, Possible mechanism of impaired calcium and vitamin D metabolism in nephrotic rats., Kidney Int.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Ma et al., 2000, [Effect of mouse p53 minigene on lung cancer cells with different 172 structures regulated by tetracycline]., Zhonghua Bing Li Xue Za Zhi
Ghosh et al., 2002, The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury., Am. J. Med. Sci.
Theodorakis et al., 1988, HSP70 mRNA translation in chicken reticulocytes is regulated at the level of elongation., J. Biol. Chem.
Lee et al., 1987, Effect of cycloheximide or puromycin on induction of thermotolerance by heat in Chinese hamster ovary cells: dose fractionation at 45.5 degrees C1., Cancer Res.
Hayashi et al., 1991, Translocation of hsp-70 and protein synthesis during continuous heating at mild temperatures in HeLa cells., Radiat. Res.
Indraccolo et al., 1993, Standardization of in vitro synthesis and detection of HIV-1-specific antibodies., J. Immunol. Methods
Marchetti et al., 2002, Endothelial cells genetically selected from differentiating mouse embryonic stem cells incorporate at sites of neovascularization in vivo., J. Cell. Sci.

PUROMYCIN RPL19

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL11

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL8

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL15

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RSL24D1

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL13A

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL10L

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL23

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL26L1

Interaction Score: 2.84

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL3

Interaction Score: 1.89

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL37

Interaction Score: 1.89

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN RPL23A

Interaction Score: 1.89

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
PUROMYCIN CD34

Interaction Score: 1.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11973349

Sources:
NCI
PUROMYCIN AGTR2

Interaction Score: 0.71

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12495295

Sources:
NCI
PUROMYCIN HSPA4

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3170555 3664499 1986403

Sources:
NCI
PUROMYCIN PTH

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1328752

Sources:
NCI
PUROMYCIN TAC1

Interaction Score: 0.26

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14623771

Sources:
NCI
PUROMYCIN FCGR3B

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8423352

Sources:
NCI
PUROMYCIN FCGR3A

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8423352

Sources:
NCI
PUROMYCIN TP53

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11866936

Sources:
NCI

DrugBank: DB08437
- Version: 5.1.7
Alternate Names:

PUROMYCIN DrugBank Drug Name

53-79-2 CAS Number

CHEMBL469912 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories acids, carbocyclic

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

NCI: PUROMYCIN

Version: 14-September-2017

Alternate Names:

C787 NCI drug code

Drug Info:

Publications:

Marvizon et al., 2003, Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord., Br. J. Pharmacol.

Indraccolo et al., 1993, Standardization of in vitro synthesis and detection of HIV-1-specific antibodies., J. Immunol. Methods

Ma et al., 2000, [Effect of mouse p53 minigene on lung cancer cells with different 172 structures regulated by tetracycline]., Zhonghua Bing Li Xue Za Zhi

ChemblDrugs: chembl:CHEMBL469912
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

PUROMYCIN	DrugBank Drug Name
53-79-2	CAS Number
CHEMBL469912	ChEMBL ID

Drug Type	small molecule
Drug Groups	experimental
Drug Categories	acids, carbocyclic

PUROMYCIN Drug Record

PUROMYCIN chembl:CHEMBL469912 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11973349

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12495295

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3170555 3664499 1986403

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1328752

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14623771

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8423352

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8423352

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
11973349

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12495295

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
3170555 3664499 1986403

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1328752

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14623771

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8423352

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8423352

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11866936

Sources:
NCI

Alternate Names:

PUROMYCIN DrugBank Drug Name

53-79-2 CAS Number

CHEMBL469912 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories acids, carbocyclic

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Alternate Names:

C787 NCI drug code