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PROTOPORPHYRIN Drug Record

  • Summary
  • Interactions
  • Claims
  • PROTOPORPHYRIN chembl:CHEMBL267548

    Alternate Names:

    Drug Info:

    Drug Groups experimental
    Drug Type small molecule
    Drug Categories biological factors
    Drug Categories dermatologicals
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories photosensitizing agents
    Drug Categories pigments, biological
    Drug Categories porphyrins
    Drug Categories radiation-sensitizing agents
    (0 More Sources)

    Publications:

    Verwanger et al., 1998, Expression kinetics of the (proto) oncogenes c-myc and bcl-2 following photodynamic treatment of normal and transformed human fibroblasts with 5-aminolaevulinic acid-stimulated endogenous protoporphyrin IX., J. Photochem. Photobiol. B, Biol.
    Malina et al., Glutathione as a cytoprotective antioxidant in erythrocytes of the newborn: the role of G6PD and zinc protoporphyrin: a hypothesis., Pediatr Hematol Oncol
    Amano et al., 1998, Inhibition of substance P-induced histamine release from rat peritoneal mast cells by low doses of protoporphyrin plus long-wave ultraviolet light irradiation: decreased intracellular calcium as a possible mechanism., Clin. Exp. Allergy
    Kábrt et al., 1982, Acute and chronic vitamin C deficiency in guinea-pigs: its effect on ceruloplasmin and cytochrome P 450 and b5 levels., Physiol Bohemoslov
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
  • PROTOPORPHYRIN   FTL

    Interaction Score: 4.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • PROTOPORPHYRIN   CP

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6214811


    Sources:
    NCI

  • PROTOPORPHYRIN   TAC1

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9677143


    Sources:
    NCI

  • PROTOPORPHYRIN   SUMO1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   MYC

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9868803


    Sources:
    NCI

  • PROTOPORPHYRIN   G6PD

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9267885


    Sources:
    NCI

  • PROTOPORPHYRIN   KMT2A

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   TDP1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   ALOX15B

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   WRN

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   RGS4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   THRB

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   RECQL

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   POLH

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   APEX1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   PLK1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   POLB

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   FEN1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   USP1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   POLI

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   POLK

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   HSD17B10

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   MAPT

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   KDM4A

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   VDR

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROTOPORPHYRIN   CYP1A2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB02285

    • Version: 5.1.7

    Alternate Names:
    PROTOPORPHYRIN DrugBank Drug Name
    553-12-8 CAS Number
    CHEMBL1325592 ChEMBL ID

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Categories biological factors

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

  • NCI: PROTOPORPHYRIN

    • Version: 14-September-2017

    Alternate Names:
    C785 NCI drug code

    Drug Info:

    Publications:
    Verwanger et al., 1998, Expression kinetics of the (proto) oncogenes c-myc and bcl-2 following photodynamic treatment of normal and transformed human fibroblasts with 5-aminolaevulinic acid-stimulated endogenous protoporphyrin IX., J. Photochem. Photobiol. B, Biol.
    Malina et al., Glutathione as a cytoprotective antioxidant in erythrocytes of the newborn: the role of G6PD and zinc protoporphyrin: a hypothesis., Pediatr Hematol Oncol
    Kábrt et al., 1982, Acute and chronic vitamin C deficiency in guinea-pigs: its effect on ceruloplasmin and cytochrome P 450 and b5 levels., Physiol Bohemoslov

  • DTC: PROTOPORPHYRIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL267548 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL267548

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21