• PRILOCAINE chembl:CHEMBL1194 Approved

    Alternate Names:

    ASTRA-1515
    CITANEST
    NSC-40027
    PRILOCAINE
    ASTRA-1512
    PROPITOCAINE
    2-(PROPYLAMINO)-O-PROPIONOTOLUIDIDE
    PRILOTEKAL®
    PRILOCAIN
    ASTRA 1512
    N-(2-METHYLPHENYL)-2-(PROPYLAMINO)PROPANAMIDE
    PRILOCAÏNE
    L-67
    2-METHYL-ALPHA-PROPYLAMINOPROPIONANILIDE
    PRILOCAINA
    O-METHYL-ALPHA-PROPYLAMINOPROPIONANILIDE
    PRILOCAINE BASE
    O-METHYL-2-PROPYLAMINOPROPIONANILIDE
    ALPHA-N-PROPYLAMINO-2-METHYLPROPIONANILIDE
    PRILOCAINUM
    pubchem.compound:4906
    chemidplus:721-50-6
    drugbank:00750
    rxcui:8686
    chembl:CHEMBL1194

    Drug Info:

    Drug Indications for treatment of premature ejaculation
    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications anesthetic
    Drug Class anesthetics, local
    Year of Approval approved before 1982
    Drug Categories amide local anesthetic
    Drug Categories amines
    Drug Categories aniline compounds
    Drug Categories local anesthesia
    (4 More Sources)
  • Interaction Score: 0.44

    Interaction Types & Directionality:
    blocker (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Trial Name Oraqix

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Combination therapy Lidocaine,Prilocaine

    PMIDs:
    None found


    Sources:
    FDA PharmGKB

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Sodium channel alpha subunit blocker

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Sodium channel alpha subunit blocker
    Direct Interaction yes

    PMIDs:
    None found