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PLICAMYCIN Drug Record

  • Summary
  • Interactions
  • Claims
  • PLICAMYCIN chembl:CHEMBL1237054 ApprovedAntineoplastic

    Alternate Names:

    PLICAMYCIN
    MITHRAMYCIN
    LA-7017
    A-2371
    MITHRACIN
    NSC-24559
    PA-144
    ANTIBIOTIC LA-7017
    MITHRAMYCINE
    AUREOLIC ACID
    PLICAMYCINE
    PLICAMYCINUM
    MITHRAMYCINUM
    chembl:CHEMBL1237054
    chemidplus:18378-89-7
    pubchem.compound:52945526
    drugbank:06810
    rxcui:6995

    Drug Info:

    (1 More Sources)

    Publications:

    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.
  • PLICAMYCIN   BIRC5

    Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17124180


    Sources:
    NCI

  • PLICAMYCIN   CYP2C9

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • PLICAMYCIN   CYP2C19

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • PLICAMYCIN   CYP1A2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • PLICAMYCIN   CYP2D6

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • PLICAMYCIN   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • NCI: MITHRAMYCIN

    • Version: 14-September-2017

    Alternate Names:
    C658 NCI drug code

    Drug Info:

    Publications:
    Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.

  • DTC: PLICAMYCIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1237054 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • TTD: Plicamycin

    • Version: 2020.06.01

    Alternate Names:
    D06EPF TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1237054

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • MyCancerGenomeClinicalTrial: PLICAMYCIN

    • Version: 30-February-2014

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21