DGIdb - PLICAMYCIN Drug Record

PLICAMYCIN chembl:CHEMBL1237054 ApprovedAntineoplastic

Alternate Names:

PLICAMYCIN
MITHRAMYCIN
LA-7017
A-2371
MITHRACIN
NSC-24559
PA-144
ANTIBIOTIC LA-7017
MITHRAMYCINE
AUREOLIC ACID
PLICAMYCINE
PLICAMYCINUM
MITHRAMYCINUM
chembl:CHEMBL1237054
chemidplus:18378-89-7
pubchem.compound:52945526
drugbank:06810
rxcui:6995

Drug Info:

(1 More Sources)

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.

PLICAMYCIN BIRC5

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17124180

Sources:
NCI
PLICAMYCIN CYP2C9

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
PLICAMYCIN CYP2C19

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
PLICAMYCIN CYP1A2

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
PLICAMYCIN CYP2D6

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
PLICAMYCIN CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC

NCI: MITHRAMYCIN
- Version: 14-September-2017
Alternate Names:

C658 NCI drug code

Drug Info:

Publications:

Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.
DTC: PLICAMYCIN
- Version: 02-September-2020
Alternate Names:

CHEMBL1237054 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
TTD: Plicamycin
- Version: 2020.06.01
Alternate Names:

D06EPF TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1237054
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
MyCancerGenomeClinicalTrial: PLICAMYCIN
- Version: 30-February-2014
Alternate Names:

Drug Info:

Publications:

PLICAMYCIN Drug Record

PLICAMYCIN chembl:CHEMBL1237054 ApprovedAntineoplastic

Alternate Names:

Drug Info:

Publications:

PLICAMYCIN BIRC5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17124180

Sources: NCI

PLICAMYCIN CYP2C9

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

PLICAMYCIN CYP2C19

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

PLICAMYCIN CYP1A2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

PLICAMYCIN CYP2D6

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

PLICAMYCIN CYP3A4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

NCI: MITHRAMYCIN

Alternate Names: C658 NCI drug code

Drug Info:

Publications: Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.

DTC: PLICAMYCIN

Alternate Names: CHEMBL1237054 ChEMBL Drug ID

Drug Info:

Publications: Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for &gt;200 compounds., Chem Res Toxicol

TTD: Plicamycin

Alternate Names: D06EPF TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1237054

Alternate Names:

Drug Info:

Publications:

MyCancerGenomeClinicalTrial: PLICAMYCIN

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
17124180

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Alternate Names:

C658 NCI drug code

Publications:

Estève et al., 2007, Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells., J. Biol. Chem.

Alternate Names:

CHEMBL1237054 ChEMBL Drug ID

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

Alternate Names:

D06EPF TTD Drug ID