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PHENOTHIAZINE Drug Record

  • Summary
  • Interactions
  • Claims
  • PHENOTHIAZINE chembl:CHEMBL828

    Alternate Names:

    NEMAZINE
    PHENTHIAZINE
    PHENOTHIAZINE
    THIODIPHENYLAMINE

    Drug Info:

    (0 More Sources)

    Publications:

    White, 1985, Evidence for a role of calmodulin in the regulation of prolactin gene expression., J. Biol. Chem.
    Debord et al., 2002, Inhibition of butyrylcholinesterase by phenothiazine derivatives., J Enzyme Inhib Med Chem
    Kónya et al., 2006, Inhibition of the MDR1 transporter by new phenothiazine derivatives., Biochem. Biophys. Res. Commun.
    Marshak et al., 1981, Calcium-dependent interaction of S100b, troponin C, and calmodulin with an immobilized phenothiazine., Proc. Natl. Acad. Sci. U.S.A.
    Epstein et al., 1975, The effect of prolonged lithium carbonate administration on the thyrotrophin and prolactin response to thyrotrophin-releasing hormone., S. Afr. Med. J.
  • PHENOTHIAZINE   S100B

    Interaction Score: 3.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6947252


    Sources:
    NCI

  • PHENOTHIAZINE   NOX1

    Interaction Score: 1.93

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   TSHB

    Interaction Score: 0.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    812185


    Sources:
    NCI

  • PHENOTHIAZINE   BCHE

    Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12443046


    Sources:
    NCI

  • PHENOTHIAZINE   PRL

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3918029


    Sources:
    NCI

  • PHENOTHIAZINE   ALOX12

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   ALOX15B

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   GAA

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   RACGAP1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   ABCB1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16750172


    Sources:
    NCI

  • PHENOTHIAZINE   PPARG

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   ALOX15

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   BAZ2B

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   MAPT

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   NFE2L2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENOTHIAZINE   EHMT2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NCI: PHENOTHIAZINE

    • Version: 14-September-2017

    Alternate Names:
    C740 NCI drug code

    Drug Info:

    Publications:
    Debord et al., 2002, Inhibition of butyrylcholinesterase by phenothiazine derivatives., J Enzyme Inhib Med Chem
    Kónya et al., 2006, Inhibition of the MDR1 transporter by new phenothiazine derivatives., Biochem. Biophys. Res. Commun.
    Epstein et al., 1975, The effect of prolonged lithium carbonate administration on the thyrotrophin and prolactin response to thyrotrophin-releasing hormone., S. Afr. Med. J.

  • DTC: PHENOTHIAZINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL828 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL828

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21