DGIdb - PHENOTHIAZINE Drug Record

PHENOTHIAZINE chembl:CHEMBL828

Alternate Names:

NEMAZINE
PHENTHIAZINE
PHENOTHIAZINE
THIODIPHENYLAMINE

Drug Info:

Drug Type	small molecule
Drug Groups	experimental
Drug Groups	vet_approved
Drug Categories	agents that reduce seizure threshold
Drug Categories	anti-infective agents
Drug Categories	antiparasitic agents
Drug Categories	antiprotozoals
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	sulfur compounds

(0 More Sources)

Publications:

White, 1985, Evidence for a role of calmodulin in the regulation of prolactin gene expression., J. Biol. Chem.
Debord et al., 2002, Inhibition of butyrylcholinesterase by phenothiazine derivatives., J Enzyme Inhib Med Chem
Kónya et al., 2006, Inhibition of the MDR1 transporter by new phenothiazine derivatives., Biochem. Biophys. Res. Commun.
Marshak et al., 1981, Calcium-dependent interaction of S100b, troponin C, and calmodulin with an immobilized phenothiazine., Proc. Natl. Acad. Sci. U.S.A.
Epstein et al., 1975, The effect of prolonged lithium carbonate administration on the thyrotrophin and prolactin response to thyrotrophin-releasing hormone., S. Afr. Med. J.
Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

PHENOTHIAZINE NOX1

Interaction Score: 1.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE S100B

Interaction Score: 0.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6947252

Sources:
NCI
PHENOTHIAZINE TSHB

Interaction Score: 0.61

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
812185

Sources:
NCI
PHENOTHIAZINE PRL

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3918029

Sources:
NCI
PHENOTHIAZINE BCHE

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12443046

Sources:
NCI
PHENOTHIAZINE ALOX12

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE ALOX15B

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE GAA

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE RACGAP1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE ABCB1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16750172

Sources:
NCI
PHENOTHIAZINE ALOX15

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE PPARG

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE BAZ2B

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE MAPT

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE AR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17606915

Sources:
DrugBank
PHENOTHIAZINE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENOTHIAZINE EHMT2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB11447
- Version: 5.1.7
Alternate Names:

PHENOTHIAZINE DrugBank Drug Name

92-84-2 CAS Number

CHEMBL828 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups vet_approved

Publications:

Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

NCI: PHENOTHIAZINE

Version: 14-September-2017

Alternate Names:

C740 NCI drug code

Drug Info:

Publications:

Debord et al., 2002, Inhibition of butyrylcholinesterase by phenothiazine derivatives., J Enzyme Inhib Med Chem

Kónya et al., 2006, Inhibition of the MDR1 transporter by new phenothiazine derivatives., Biochem. Biophys. Res. Commun.

Epstein et al., 1975, The effect of prolonged lithium carbonate administration on the thyrotrophin and prolactin response to thyrotrophin-releasing hormone., S. Afr. Med. J.

DTC: PHENOTHIAZINE
- Version: 02-September-2020
Alternate Names:

CHEMBL828 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL828
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

PHENOTHIAZINE	DrugBank Drug Name
92-84-2	CAS Number
CHEMBL828	ChEMBL ID

PHENOTHIAZINE Drug Record

PHENOTHIAZINE chembl:CHEMBL828

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6947252

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 812185

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3918029

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12443046

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16750172

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17606915

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

DrugBank: DB11447

Alternate Names: PHENOTHIAZINE DrugBank Drug Name 92-84-2 CAS Number CHEMBL828 ChEMBL ID

Drug Info: Drug Type small molecule Drug Groups experimental Drug Groups vet_approved

Publications: Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

NCI: PHENOTHIAZINE

Alternate Names: C740 NCI drug code

Drug Info:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
6947252

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
812185

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
3918029

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12443046

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16750172

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
17606915

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

PHENOTHIAZINE DrugBank Drug Name

92-84-2 CAS Number

CHEMBL828 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Groups vet_approved

Publications:

Bisson WH et al., 2007, Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs., Proc Natl Acad Sci U S A

Alternate Names:

C740 NCI drug code

Alternate Names:

CHEMBL828 ChEMBL Drug ID