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PERFOSFAMIDE Drug Record

  • Summary
  • Interactions
  • Claims
  • PERFOSFAMIDE chembl:CHEMBL61511

    Alternate Names:

    4-HC
    PERGAMID
    NSC-181815
    PERFOSFAMIDE
    4-HYDROPEROXYCYCLOPHOSPHAMIDE

    Drug Info:

    (0 More Sources)

    Publications:

    Laver et al., 1992, Effects of radiation and 4-hydroperoxycyclophosphamide on production of G- and GM-CSF by stromal cells., Bone Marrow Transplant.
    Takebe et al., 2001, Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene., Mol. Ther.
    Clutter et al., 2006, Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells., Exp. Hematol.
    Kuga et al., 1997, Fibronectin fragment-facilitated retroviral transfer of the glutathione-S-transferase pi gene into CD34+ cells to protect them against alkylating agents., Hum. Gene Ther.
    Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.
    Abdul Hamied et al., 1987, Effects of adriamycin, 4-hydroperoxycyclophosphamide and ASTA Z 7557 (INN mafosfamide) on the release of IL-2 and IL-1 in vitro., Int. J. Immunopharmacol.
  • PERFOSFAMIDE   DHFR

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11162315


    Sources:
    NCI

  • PERFOSFAMIDE   TGM2

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8828830


    Sources:
    NCI

  • PERFOSFAMIDE   MMP2

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17046572


    Sources:
    NCI

  • PERFOSFAMIDE   IL2

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3497116


    Sources:
    NCI

  • PERFOSFAMIDE   CSF2

    Interaction Score: 0.5

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1283360


    Sources:
    NCI

  • PERFOSFAMIDE   GSTP1

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9382956


    Sources:
    NCI

  • NCI: 4-HYDROPEROXYCYCLOPHOSPHAMIDE

    • Version: 14-September-2017

    Alternate Names:
    C1423 NCI drug code

    Drug Info:

    Publications:
    Clutter et al., 2006, Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells., Exp. Hematol.
    Adel Moallem et al., 1996, Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse., Biol. Reprod.
    Takebe et al., 2001, Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene., Mol. Ther.

  • NCI: 4-HC

    • Version: 14-September-2017

    Alternate Names:
    C1423 NCI drug code

    Drug Info:

    Publications:
    Laver et al., 1992, Effects of radiation and 4-hydroperoxycyclophosphamide on production of G- and GM-CSF by stromal cells., Bone Marrow Transplant.

  • ChemblDrugs: chembl:CHEMBL61511

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21