PERAMPANEL |
FYCOMPA |
ER-155055-90 |
E2007 |
E-2007 |
PERAMPANELUM |
E 2007 |
PÉRAMPANEL |
FYCOMPA® |
3-(2-CYANOPHENYL)-5-(2-PYRIDYL)-1-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE |
drugbank:08883 |
chembl:CHEMBL1214124 |
pubchem.compound:9924495 |
rxcui:1356552 |
chemidplus:380917-97-5 |
FDA Approval | not approved |
Drug Class | Small molecule |
Drug Indications | anticonvulsant |
Drug Categories | ampa receptor antagonists |
Drug Categories | cytochrome p-450 cyp1a2 substrates |
Drug Categories | cytochrome p-450 cyp2b6 inducers |
Drug Categories | cytochrome p-450 cyp2b6 inducers (weak) |
Drug Categories | cytochrome p-450 cyp2b6 substrates |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inducers |
Drug Categories | cytochrome p-450 cyp3a4 inducers (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a5 substrates |
Drug Categories | cytochrome p-450 enzyme inducers |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | miscellaneous anticonvulsants |
Drug Categories | noncompetitive ampa glutamate receptor antagonist |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Trial Name | E2007 |
antagonist (inhibitory) |
Trial Name | E2007 |
Novel drug target | Established target |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
Trial Name | E2007 |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
Trial Name | E2007 |
PERAMPANEL | DrugBank Drug Name |
380917-97-5 | CAS Number |
Fycompa | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | ampa receptor antagonists |
Drug Indications | anticonvulsant |
Drug Class | Small molecule |
FDA Approval | not approved |
D0U3ED | TTD Drug ID |