DGIdb - PENTAGASTRIN Drug Record

PENTAGASTRIN chembl:CHEMBL1328 Approved

Alternate Names:

PENTAGASTRIN
AY-6608
ICI-50123
PEPTAVLON
drugbank:00183
chembl:CHEMBL1328
rxcui:7993
chemidplus:5534-95-2
pubchem.compound:9853654

Drug Info:

Drug Class	diagnostic agents
Year of Approval	1974
Drug Categories	tests for gastric secretion
Drug Categories	gastrins
FDA Approval	1974
Drug Class	small molecule
Drug Indications	Diagnostic Agents
Drug Categories	pentagastrin, antagonists & inhibitors

(1 More Sources)

Publications:

Singh et al., 1986, Role of gastrin and gastrin receptors on the growth of a transplantable mouse colon carcinoma (MC-26) in BALB/c mice., Cancer Res.
Nishida et al., 1995, Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression., Am. J. Physiol.
Makovec et al., 1992, Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives., J. Med. Chem.
Khan et al., 2004, Effect of repeat exposure on neuroendocrine and symptom responses to pentagastrin., Psychiatry Res
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Radu et al., 2002, Anxiogenic effects of the CCK(B) agonist pentagastrin in humans and dose-dependent increase in plasma C-peptide levels., Psychopharmacology (Berl.)

PENTAGASTRIN CCKBR

Interaction Score: 27.05

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
3004700 7491961 1732532 15157745 11752352 12073167

Sources:
TEND TdgClinicalTrial TTD DrugBank

DrugBank: DB00183

Version: 5.1.7

Alternate Names:

PENTAGASTRIN DrugBank Drug Name

5534-95-2 CAS Number

Pentagastrin Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories amino acids, peptides, and proteins

Publications:

Singh et al., 1986, Role of gastrin and gastrin receptors on the growth of a transplantable mouse colon carcinoma (MC-26) in BALB/c mice., Cancer Res.

Nishida et al., 1995, Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression., Am. J. Physiol.

Makovec et al., 1992, Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives., J. Med. Chem.

TEND: PENTAGASTRIN
- Version: 01-August-2011
Alternate Names:

PENTAGASTRIN Primary Drug Name

Drug Info:

Year of Approval 1974

Drug Class diagnostic agents

Publications:
TdgClinicalTrial: PENTAGASTRIN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Diagnostic Agents

Drug Class small molecule

FDA Approval 1974

Publications:
TTD: Pentagastrin
- Version: 2020.06.01
Alternate Names:

D0O5TQ TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1328
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

PENTAGASTRIN	DrugBank Drug Name
5534-95-2	CAS Number
Pentagastrin	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Categories	amino acids, peptides, and proteins

Trial Name	-
Novel drug target	Established target

PENTAGASTRIN Drug Record

PENTAGASTRIN chembl:CHEMBL1328 Approved

Alternate Names:

Drug Info:

Publications:

PENTAGASTRIN CCKBR

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 3004700 7491961 1732532 15157745 11752352 12073167

Sources: TEND TdgClinicalTrial TTD DrugBank

DrugBank: DB00183

Alternate Names: PENTAGASTRIN DrugBank Drug Name 5534-95-2 CAS Number Pentagastrin Drug Brand

Drug Info: Drug Type small molecule Drug Groups approved Drug Categories amino acids, peptides, and proteins

TEND: PENTAGASTRIN

Alternate Names: PENTAGASTRIN Primary Drug Name

Drug Info: Year of Approval 1974 Drug Class diagnostic agents

Publications:

TdgClinicalTrial: PENTAGASTRIN

Alternate Names:

Drug Info: Drug Indications Diagnostic Agents Drug Class small molecule FDA Approval 1974

Publications:

TTD: Pentagastrin

Alternate Names: D0O5TQ TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1328

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
3004700 7491961 1732532 15157745 11752352 12073167

Sources:
TEND TdgClinicalTrial TTD DrugBank

Alternate Names:

PENTAGASTRIN DrugBank Drug Name

5534-95-2 CAS Number

Pentagastrin Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories amino acids, peptides, and proteins

Alternate Names:

PENTAGASTRIN Primary Drug Name

Drug Info:

Year of Approval 1974

Drug Class diagnostic agents

Drug Info:

Drug Indications Diagnostic Agents

Drug Class small molecule

FDA Approval 1974

Alternate Names:

D0O5TQ TTD Drug ID