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PELITINIB Drug Record

  • Summary
  • Interactions
  • Claims
  • PELITINIB chembl:CHEMBL607707 Antineoplastic

    Alternate Names:

    WAY-EKB-569
    PELITINIB
    EKB-569

    Drug Info:

    Drug Class Kinase Inhibitors
    (2 More Sources)

    Publications:

    Erlichman et al., 2006, Phase I study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor, in patients with advanced solid tumors., J. Clin. Oncol.
    Yoshimura et al., 2006, EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib., Lung Cancer
  • PELITINIB   ERBB4

    Interaction Score: 1.25

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome

  • PELITINIB   EGFR

    Interaction Score: 0.86

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Epidermal growth factor receptor erbB1 inhibitor
    Indication/Tumor Type Advanced Solid Tumor

    PMIDs:
    16710023 16364494


    Sources:
    TALC MyCancerGenome JAX-CKB ChemblInteractions TTD

  • PELITINIB   ERBB2

    Interaction Score: 0.28

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome

  • MyCancerGenome: PELITINIB

    • Version: 20-Jun-2017

    Alternate Names:
    EKB-569 Development Name
    PELITINIB Generic Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

  • JAX-CKB: Pelitinib

    • Version: 27-September-2017

    Alternate Names:

    Drug Info:

    Publications:
    Erlichman et al., 2006, Phase I study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor, in patients with advanced solid tumors., J. Clin. Oncol.
    Yoshimura et al., 2006, EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib., Lung Cancer

  • TTD: Pelitinib

    • Version: 2020.06.01

    Alternate Names:
    D0S3PO TTD Drug ID

    Drug Info:

    Publications:

  • TALC: PELITINIB

    • Version: 12-May-2016

    Alternate Names:
    PELITINIB Primary Drug Name
    PELITINIB Drug Generic Name
    EKB-569 Drug Synonym

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL607707

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL607707

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21