PAZOPANIB Drug Record
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PAZOPANIB chembl:CHEMBL477772 ApprovedAntineoplasticImmunotherapy
Alternate Names:
PAZOPANIB GW786034 VOTRIENT GW 78603 INDAZOLYLPYRIMIDINE 13 GW 786034 PZP034 chembl:CHEMBL477772 chemidplus:444731-52-6 drugbank:06589 pubchem.compound:10113978 rxcui:714438 Drug Info:
FDA Approval Renal cell carcinoma Drug Class Kinase Inhibitors Drug Categories receptors, vascular endothelial growth factor, antagonists & inhibitors FDA Approval approved Drug Class small molecule Drug Indications antineoplastic agent Drug Categories cytochrome p-450 cyp2c8 inhibitors Drug Categories cytochrome p-450 cyp2c8 inhibitors (weak) Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 cyp3a4 inhibitors Drug Categories cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index Drug Categories cytochrome p-450 enzyme inhibitors Drug Categories cytochrome p-450 substrates Drug Categories hepatotoxic agents Drug Categories kinase inhibitor Drug Categories oatp1b1/slco1b1 inhibitors Drug Categories p-glycoprotein substrates Drug Categories qtc prolonging agents Drug Categories tyrosine kinase inhibitors Publications:
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inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name Pazopanib Notes -
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inhibitor (inhibitory) Interaction Info:
Trial Name Pazopanib Novel drug target Established target Notes -
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inhibitor (inhibitory) Interaction Info:
Notes Specific Action of the Ligand Inhibition Endogenous Drug? False -
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inhibitor (inhibitory) Interaction Info:
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inhibitor (inhibitory) Interaction Info:
Notes Specific Action of the Ligand Inhibition Endogenous Drug? False PMIDs:
17288876
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inhibitor (inhibitory) Interaction Info:
Notes Specific Action of the Ligand Inhibition Endogenous Drug? False PMIDs:
17288876
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n/a Interaction Info:
combination therapy Everolimus;Pazopanib Drug family MTOR inhibitor;VEGFR inhibitor Alteration NF1:. -
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inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False
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Alternate Names:
PAZOPANIB DrugBank Drug Name 444731-52-6 CAS Number Votrient Drug Brand Drug Info:
Drug Type small molecule Drug Groups approved Drug Categories amides -
- Version: 20-Jun-2017
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PAZOPANIB Generic Name VOTRIENT Trade Name Drug Info:
Drug Class Kinase Inhibitors FDA Approval Renal cell carcinoma Publications:
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- Version: January-2014
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Drug Indications antineoplastic agent Drug Class small molecule FDA Approval approved Publications:
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CHEMBL477772 ChEMBL Drug ID Drug Info:
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PAZOPANIB Primary Drug Name PAZOPANIB Drug Generic Name VOTRIENT Drug Trade Name Drug Info:
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- Version: 29-September-2020
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PAZOPANIB GuideToPharmacology Ligand Name Drug Info:
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- Version: ChEMBL_27
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- Version: 30-February-2014
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