PAZOPANIB |
GW786034 |
VOTRIENT |
GW 78603 |
INDAZOLYLPYRIMIDINE 13 |
GW 786034 |
PZP034 |
chembl:CHEMBL477772 |
chemidplus:444731-52-6 |
drugbank:06589 |
pubchem.compound:10113978 |
rxcui:714438 |
FDA Approval | Renal cell carcinoma |
Drug Class | Kinase Inhibitors |
Drug Categories | receptors, vascular endothelial growth factor, antagonists & inhibitors |
FDA Approval | approved |
Drug Class | small molecule |
Drug Indications | antineoplastic agent |
Drug Categories | cytochrome p-450 cyp2c8 inhibitors |
Drug Categories | cytochrome p-450 cyp2c8 inhibitors (weak) |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 substrates with a narrow therapeutic index |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | hepatotoxic agents |
Drug Categories | kinase inhibitor |
Drug Categories | oatp1b1/slco1b1 inhibitors |
Drug Categories | p-glycoprotein substrates |
Drug Categories | qtc prolonging agents |
Drug Categories | tyrosine kinase inhibitors |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Pazopanib |
Notes |
inhibitor (inhibitory) |
Trial Name | Pazopanib |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Notes | |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes | |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Notes | |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
n/a |
combination therapy | Everolimus;Pazopanib |
Drug family | MTOR inhibitor;VEGFR inhibitor |
Alteration | NF1:. |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
PAZOPANIB | DrugBank Drug Name |
444731-52-6 | CAS Number |
Votrient | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | amides |
PAZOPANIB | Generic Name |
VOTRIENT | Trade Name |
Drug Class | Kinase Inhibitors |
FDA Approval | Renal cell carcinoma |
Drug Indications | antineoplastic agent |
Drug Class | small molecule |
FDA Approval | approved |
CHEMBL477772 | ChEMBL Drug ID |
PAZOPANIB | Primary Drug Name |
PAZOPANIB | Drug Generic Name |
VOTRIENT | Drug Trade Name |
PAZOPANIB | GuideToPharmacology Ligand Name |