PEXEVA |
PAXIL |
BRL-29060 |
PAROXETINE |
PAXIL [AS HYDROCHLORIDE] |
(−)-(3S,4R)-4-(P-FLUOROPHENYL)-3-((3,4-(METHYLENEDIOXY)PHENOXY)METHYL)PIPERIDINE |
(3S-TRANS)-3-((1,3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)PIPERIDINE |
PAROXETINUM |
(-)-(3S,4R)-4-(P-FLUOROPHENYL)-3-((3,4-(METHYLENEDIOXY)PHENOXY)METHYL)PIPERIDINE |
PAROXETINA |
pubchem.compound:43815 |
chembl:CHEMBL490 |
drugbank:00715 |
chemidplus:61869-08-7 |
rxcui:32937 |
FDA Approval | approved |
Drug Class | Small Molecule |
Drug Indications | antidepressant |
Drug Class | antidepressive agents, second-generation |
Year of Approval | 1992 |
Drug Categories | agents producing tachycardia |
Drug Categories | anticholinergic agents |
Drug Categories | central nervous system depressants |
Drug Categories | cytochrome p-450 cyp1a2 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp1a2 substrates |
Drug Categories | cytochrome p-450 cyp2b6 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c19 inhibitors |
Drug Categories | cytochrome p-450 cyp2c19 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp2c19 substrates |
Drug Categories | cytochrome p-450 cyp2c9 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a inhibitors |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a4 substrates |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | drugs causing inadvertant photosensitivity |
Drug Categories | hypoglycemia-associated agents |
Drug Categories | muscarinic antagonists |
Drug Categories | p-glycoprotein inhibitors |
Drug Categories | photosensitizing agents |
Drug Categories | serotonergic drugs shown to increase risk of serotonin syndrome |
antagonist (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
inhibitor (inhibitory) |
Trial Name | CRx-139 |
Novel drug target | Established target |
Trial Name | paroxetine hydrochloride,Paxil, Seroxat |
PAROXETINE | DrugBank Drug Name |
61869-08-7 | CAS Number |
Act Paroxetine | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | investigational |
PAROXETINE | Primary Drug Name |
Year of Approval | 1992 |
Drug Class | antidepressive agents, second-generation |
Drug Indications | antidepressant |
Drug Class | Small Molecule |
FDA Approval | approved |
D06GDY | TTD Drug ID |
PAROXETINE | GuideToPharmacology Ligand Name |
CHEMBL490 | ChEMBL Drug ID |