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NOVOBIOCIN Drug Record

  • Summary
  • Interactions
  • Claims
  • NOVOBIOCIN chembl:CHEMBL36506

    Alternate Names:

    ALBAMYCIN T
    CATHOMYCIN
    NOVOBIOCIN
    ALBAMYCIN
    NOVOBIOCINUM
    N-{7-[(3-O-CARBAMOYL-6-DEOXY-5-METHYL-4-O-METHYL-BETA-D-GULOPYRANOSYL)OXY]-4-HYDROXY-8-METHYL-2-OXO-2H-CHROMEN-3-YL}-4-HYDROXY-3-(3-METHYLBUT-2-EN-1-YL)BENZAMIDE
    NOVOBIOCINA
    NOVOBIOCINE
    drugbank:01051
    chemidplus:303-81-1
    rxcui:7538
    chembl:CHEMBL36506
    pubchem.compound:54675769

    Drug Info:

    (0 More Sources)

    Publications:

    Rappa et al., 2000, Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells., Anticancer Drug Des.
    Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem
    Aller et al., 1986, Selective increase of c-myc mRNA levels by methylglyoxal-bis (guanylhydrazone) and novobiocin in serum-stimulated fibroblasts., J. Cell. Physiol.
    Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem
  • NOVOBIOCIN   MYC

    Interaction Score: 0.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3528175


    Sources:
    NCI

  • NOVOBIOCIN   HSP90AB1

    Interaction Score: 0.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23859777


    Sources:
    DTC

  • NOVOBIOCIN   ABCC1

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10901300


    Sources:
    NCI

  • NOVOBIOCIN   TOP2B

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • NOVOBIOCIN   HSP90AA1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21129982 23859777


    Sources:
    DTC

  • DTC: NOVOBIOCIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL36506 ChEMBL Drug ID

    Drug Info:

    Publications:
    Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem
    Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

  • NCI: NOVOBIOCIN

    • Version: 14-September-2017

    Alternate Names:
    C705 NCI drug code

    Drug Info:

    Publications:
    Aller et al., 1986, Selective increase of c-myc mRNA levels by methylglyoxal-bis (guanylhydrazone) and novobiocin in serum-stimulated fibroblasts., J. Cell. Physiol.
    Rappa et al., 2000, Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells., Anticancer Drug Des.

  • TTD: Novobiocin

    • Version: 2020.06.01

    Alternate Names:
    D0Q0PR TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL36506

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21