DGIdb - NOVOBIOCIN Drug Record

NOVOBIOCIN chembl:CHEMBL36506

Alternate Names:

ALBAMYCIN T
CATHOMYCIN
NOVOBIOCIN
ALBAMYCIN
NOVOBIOCINUM
N-{7-[(3-O-CARBAMOYL-6-DEOXY-5-METHYL-4-O-METHYL-BETA-D-GULOPYRANOSYL)OXY]-4-HYDROXY-8-METHYL-2-OXO-2H-CHROMEN-3-YL}-4-HYDROXY-3-(3-METHYLBUT-2-EN-1-YL)BENZAMIDE
NOVOBIOCINA
NOVOBIOCINE
drugbank:01051
chemidplus:303-81-1
rxcui:7538
chembl:CHEMBL36506
pubchem.compound:54675769

Drug Info:

(0 More Sources)

Publications:

Rappa et al., 2000, Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells., Anticancer Drug Des.
Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem
Aller et al., 1986, Selective increase of c-myc mRNA levels by methylglyoxal-bis (guanylhydrazone) and novobiocin in serum-stimulated fibroblasts., J. Cell. Physiol.
Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

NOVOBIOCIN HSP90AB1

Interaction Score: 0.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23859777

Sources:
DTC
NOVOBIOCIN MYC

Interaction Score: 0.62

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3528175

Sources:
NCI
NOVOBIOCIN ABCC1

Interaction Score: 0.51

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10901300

Sources:
NCI
NOVOBIOCIN TOP2B

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
NOVOBIOCIN HSP90AA1

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21129982 23859777

Sources:
DTC

DTC: NOVOBIOCIN

Version: 02-September-2020

Alternate Names:

CHEMBL36506 ChEMBL Drug ID

Drug Info:

Publications:

Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem

Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

NCI: NOVOBIOCIN

Version: 14-September-2017

Alternate Names:

C705 NCI drug code

Drug Info:

Publications:

Aller et al., 1986, Selective increase of c-myc mRNA levels by methylglyoxal-bis (guanylhydrazone) and novobiocin in serum-stimulated fibroblasts., J. Cell. Physiol.

Rappa et al., 2000, Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells., Anticancer Drug Des.

TTD: Novobiocin
- Version: 2020.06.01
Alternate Names:

D0Q0PR TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL36506
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

NOVOBIOCIN Drug Record

NOVOBIOCIN chembl:CHEMBL36506

Alternate Names:

Drug Info:

Publications:

NOVOBIOCIN HSP90AB1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23859777

Sources: DTC

NOVOBIOCIN MYC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3528175

Sources: NCI

NOVOBIOCIN ABCC1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10901300

Sources: NCI

NOVOBIOCIN TOP2B

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

NOVOBIOCIN HSP90AA1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21129982 23859777

Sources: DTC

DTC: NOVOBIOCIN

Alternate Names: CHEMBL36506 ChEMBL Drug ID

Drug Info:

Publications: Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

NCI: NOVOBIOCIN

Alternate Names: C705 NCI drug code

Drug Info:

TTD: Novobiocin

Alternate Names: D0Q0PR TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL36506

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
23859777

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
3528175

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10901300

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
21129982 23859777

Sources:
DTC

Alternate Names:

CHEMBL36506 ChEMBL Drug ID

Publications:

Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem

Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

Alternate Names:

C705 NCI drug code

Alternate Names:

D0Q0PR TTD Drug ID