DGIdb - MIRTAZAPINE Drug Record

MIRTAZAPINE chembl:CHEMBL654 Approved

Alternate Names:

MIRTAZAPINE
REMERON
REMERON SOLTAB
ORG-3770
ZISPIN
1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO(2,1-A)PYRIDO(2,3-C)BENZAZEPINE
6-AZAMIANSERIN
MEPIRZAPINE
MIRTAZAPINA
MIRTAZAPIN
REMERON®
MIRTAZAPINUM
2-METHYL-1,2,3,4,10,14B-HEXAHYDROPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE
chemidplus:85650-52-8
pubchem.compound:4205
chemidplus:61337-67-5
chembl:CHEMBL654
rxcui:15996
drugbank:00370

Drug Info:

FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	antidepressant
Drug Class	antidepressive agents, tricyclic
Year of Approval	1996
Drug Categories	adrenergic alpha-2 receptor antagonists
Drug Categories	agents that produce hypertension
Drug Categories	anti-anxiety agents
Drug Categories	antidepressive agents, tetracyclic
Drug Categories	cytochrome p-450 cyp3a substrates
Drug Categories	cytochrome p-450 cyp3a4 inhibitors
Drug Categories	cytochrome p-450 cyp3a4 inhibitors (weak)
Drug Categories	cytochrome p-450 enzyme inhibitors
Drug Categories	cytochrome p-450 substrates
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	miscellaneous antidepressants
Drug Categories	potential qtc-prolonging agents
Drug Categories	qtc prolonging agents
Drug Categories	serotonergic drugs shown to increase risk of serotonin syndrome
Drug Categories	serotonin 5-ht2 receptor antagonists
Drug Categories	serotonin 5-ht3 receptor antagonists
Drug Categories	serotonin agents
Drug Categories	serotonin receptor antagonists
Drug Categories	tranquilizing agents

(6 More Sources)

Publications:

Kraus et al., 2002, Body weight, the tumor necrosis factor system, and leptin production during treatment with mirtazapine or venlafaxine., Pharmacopsychiatry
Millan et al., 2000, Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram., Eur. J. Neurosci.
Nutt D, 1997, Mirtazapine: pharmacology in relation to adverse effects., Acta Psychiatr Scand Suppl
Fernández et al., 2005, Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents., J. Med. Chem.
Wikström et al., 2002, Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine., J. Med. Chem.
de Boer et al., 1988, Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers., Neuropharmacology
Kast et al., 2007, Cancer chemotherapy and cachexia: mirtazapine and olanzapine are 5-HT3 antagonists with good antinausea effects., Eur J Cancer Care (Engl)
Anttila et al., 2001, A review of the pharmacological and clinical profile of mirtazapine., CNS Drug Rev
Gorman, 1999, Mirtazapine: clinical overview., J Clin Psychiatry
de Boer, 1995, The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission., Int Clin Psychopharmacol
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Westenberg, 1999, Pharmacology of antidepressants: selectivity or multiplicity?, J Clin Psychiatry
Schreiber et al., Venlafaxine and mirtazapine: different mechanisms of antidepressant action, common opioid-mediated antinociceptive effects--a possible opioid involvement in severe depression?, J. Mol. Neurosci.
Haddjeri N et al., 1997, Effects of long-term treatment with the alpha 2-adrenoceptor antagonist mirtazapine on 5-HT neurotransmission., Naunyn Schmiedebergs Arch Pharmacol
Rogóz et al., Effect of repeated treatment with mirtazapine on the central dopaminergic D2/D3 receptors., Pol J Pharmacol
García-Sevilla et al., 2004, Regulation of platelet alpha 2A-adrenoceptors, Gi proteins and receptor kinases in major depression: effects of mirtazapine treatment., Neuropsychopharmacology
Lee HY et al., 2009, Association of the adrenergic alpha 2a receptor--1291C/G polymorphism with weight change and treatment response to mirtazapine in patients with major depressive disorder., Brain Res
Rogoz et al., 2002, Effect of repeated treatment with mirtazapine on the central alpha1-adrenergic receptors., J. Physiol. Pharmacol.
Besson et al., 2000, Effects of the co-administration of mirtazapine and paroxetine on serotonergic neurotransmission in the rat brain., Eur Neuropsychopharmacol
Pawlyk AC et al., 2006, Effects of the 5-HT2A antagonist mirtazapine in rat models of thermoregulation., Brain Res
Celada P et al., 2004, The therapeutic role of 5-HT1A and 5-HT2A receptors in depression., J Psychiatry Neurosci
Nutt, 1999, Care of depressed patients with anxiety symptoms., J Clin Psychiatry
Waldinger et al., 2000, Treatment of hot flushes with mirtazapine: four case reports., Maturitas
Laakmann et al., 1999, Effects of mirtazapine on growth hormone, prolactin, and cortisol secretion in healthy male subjects., Psychoneuroendocrinology
Millan, Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies., Therapie
Dekeyne et al., 2001, Following long-term training with citalopram, both mirtazapine and mianserin block its discriminative stimulus properties in rats., Psychopharmacology (Berl.)
Meert et al., 1997, Antagonism of meta-chlorophenylpiperazine-induced inhibition of exploratory activity in an emergence procedure, the open field test, in rats., Behav Pharmacol
Benelli et al., 2004, Influence of mirtazapine on the sexual behavior of male rats., Psychopharmacology (Berl.)
Zanger UM et al., 2008, Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation., Anal Bioanal Chem
Delacrétaz A et al., 2017, Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs., Gene
Tzvetkov MV et al., 2008, Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment., Pharmacogenet Genomics
Olianas et al., 2012, The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors., Br. J. Pharmacol.
Peckham AM et al., 2018, Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression?, Ment Health Clin
Schreiber et al., 2002, The antinociceptive effect of mirtazapine in mice is mediated through serotonergic, noradrenergic and opioid mechanisms., Brain Res. Bull.
Sato H et al., 2013, Histamine H₁ receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers., Psychopharmacology (Berl)
Salvi V et al., 2016, H1-histamine receptor affinity predicts weight gain with antidepressants., Eur Neuropsychopharmacol
Vande Griend JP et al., 2012, Histamine-1 receptor antagonism for treatment of insomnia., J Am Pharm Assoc (2003)
Jaquenoud Sirot E et al., 2012, Multicenter study on the clinical effectiveness, pharmacokinetics, and pharmacogenetics of mirtazapine in depression., J Clin Psychopharmacol
Zou YF et al., 2010, Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders., Neurosci Lett
Binder EB et al., 2004, Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment., Nat Genet
Heiser et al., 2006, Effects of different antipsychotics and the antidepressant mirtazapine on glucose transporter mRNA levels in human blood cells., J Psychiatr Res

MIRTAZAPINE FKBP5

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20709156 15565110

Sources:
PharmGKB
MIRTAZAPINE TPH2

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18496129

Sources:
PharmGKB
MIRTAZAPINE RABEP1

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28694205

Sources:
PharmGKB
MIRTAZAPINE SH2B1

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28694205

Sources:
PharmGKB
MIRTAZAPINE GAL

Interaction Score: 0.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
MIRTAZAPINE LEP

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12518269

Sources:
NCI
MIRTAZAPINE HTR3A

Interaction Score: 0.33

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex

Novel drug target Established target

PMIDs:
17587360 11607047 10446735 8930006 11752352 10446734

Sources:
TEND TdgClinicalTrial
MIRTAZAPINE ADRA2A

Interaction Score: 0.27

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
11931344 9007838 12523492 14628003 11607047 8930006 19401164 11939713 10793320

Sources:
TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions
MIRTAZAPINE HTR2C

Interaction Score: 0.22

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? True

PMIDs:
16433010 11271412 10762339 9832994 11752352 14615872

Sources:
TEND TTD DrugBank GuideToPharmacology ChemblInteractions
MIRTAZAPINE HTR2A

Interaction Score: 0.18

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Serotonin 2a (5-HT2a) receptor antagonist

Direct Interaction yes

Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex

PMIDs:
17067560 15309042 10446738 11607047 11063897 10446735 10446734 10451911

Sources:
TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions
MIRTAZAPINE SLC2A4

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16002093

Sources:
NCI
MIRTAZAPINE CYP2B6

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22926595

Sources:
PharmGKB
MIRTAZAPINE ADRA2C

Interaction Score: 0.1

Interaction Types & Directionality:

binder

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
15771415 3419539

Sources:
GuideToPharmacology ChemblInteractions
MIRTAZAPINE OPRK1

Interaction Score: 0.09

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
22708686 30155392 12372565

Sources:
DrugBank
MIRTAZAPINE ADRA1A

Interaction Score: 0.09

Interaction Types & Directionality:

binder

antagonist (inhibitory)

Interaction Info:

PMIDs:
10762339 9265949 15771415 12109911 3419539

Sources:
DrugBank
MIRTAZAPINE HRH1

Interaction Score: 0.07

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
23728612 27593622 23229983 11752352

Sources:
DrugBank
MIRTAZAPINE ADRA2B

Interaction Score: 0.06

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction? True

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology ChemblInteractions
MIRTAZAPINE CYP3A5

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18695978

Sources:
PharmGKB
MIRTAZAPINE HTR1A

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TEND
MIRTAZAPINE CYP2C9

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MIRTAZAPINE CYP2C19

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MIRTAZAPINE CYP2D6

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB00370

Version: 5.1.7

Alternate Names:

MIRTAZAPINE DrugBank Drug Name

85650-52-8 CAS Number

Apo-mirtazapine Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories adrenergic agents

Publications:

Davis R et al., 1996, Mirtazapine : A Review of its Pharmacology and Therapeutic Potential in the Management of Major Depression., CNS Drugs

Thompson AJ et al., 2007, The 5-HT3 receptor as a therapeutic target., Expert Opin Ther Targets

Bell SN et al., 1985, Tibia vara caused by focal fibrocartilaginous dysplasia. Three case reports., J Bone Joint Surg Br

TEND: MIRTAZAPINE
- Version: 01-August-2011
Alternate Names:

MIRTAZAPINE Primary Drug Name

Drug Info:

Year of Approval 1996

Drug Class antidepressive agents, tricyclic

Publications:
TdgClinicalTrial: MIRTAZAPINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications antidepressant

Drug Class Small Molecule

FDA Approval approved

Publications:

NCI: MIRTAZAPINE

Version: 14-September-2017

Alternate Names:

C29265 NCI drug code

Drug Info:

Publications:

Kraus et al., 2002, Body weight, the tumor necrosis factor system, and leptin production during treatment with mirtazapine or venlafaxine., Pharmacopsychiatry

Heiser et al., 2006, Effects of different antipsychotics and the antidepressant mirtazapine on glucose transporter mRNA levels in human blood cells., J Psychiatr Res

PharmGKB: mirtazapine

Version: 18-August-2020

Alternate Names:

Drug Info:

Publications:

Delacrétaz A et al., 2017, Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs., Gene

Tzvetkov MV et al., 2008, Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment., Pharmacogenet Genomics

Zanger UM et al., 2008, Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation., Anal Bioanal Chem

GuideToPharmacology: 178103815
- Version: 29-September-2020
Alternate Names:

MIRTAZAPINE GuideToPharmacology Ligand Name

Drug Info:

Publications:
DTC: MIRTAZAPINE
- Version: 02-September-2020
Alternate Names:

CHEMBL654 ChEMBL Drug ID

Drug Info:

Publications:
TTD: Mirtazapine
- Version: 2020.06.01
Alternate Names:

D05ZIK TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL654
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL654
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

Trial Name	mirtazapine,Remeron, Remeron SolTab, Reflex
Novel drug target	Established target

Mechanism of Interaction	Adrenergic receptor alpha-2 antagonist
Direct Interaction	yes
Specific Action of the Ligand	Antagonist

Specific Action of the Ligand	Antagonist
Endogenous Drug?	False
Direct Interaction?	True

Mechanism of Interaction	Serotonin 2a (5-HT2a) receptor antagonist
Direct Interaction	yes
Trial Name	mirtazapine,Remeron, Remeron SolTab, Reflex

MIRTAZAPINE	DrugBank Drug Name
85650-52-8	CAS Number
Apo-mirtazapine	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Categories	adrenergic agents

binder
antagonist (inhibitory)

binder
antagonist (inhibitory)

MIRTAZAPINE Drug Record

MIRTAZAPINE chembl:CHEMBL654 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20709156 15565110

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18496129

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28694205

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28694205

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12518269

Sources: NCI

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex Novel drug target Established target

PMIDs: 17587360 11607047 10446735 8930006 11752352 10446734

Sources: TEND TdgClinicalTrial

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Adrenergic receptor alpha-2 antagonist Direct Interaction yes Specific Action of the Ligand Antagonist

PMIDs: 11931344 9007838 12523492 14628003 11607047 8930006 19401164 11939713 10793320

Sources: TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False Direct Interaction? True

PMIDs: 16433010 11271412 10762339 9832994 11752352 14615872

Sources: TEND TTD DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Serotonin 2a (5-HT2a) receptor antagonist Direct Interaction yes Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex

PMIDs: 17067560 15309042 10446738 11607047 11063897 10446735 10446734 10451911

Sources: TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16002093

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22926595

Sources: PharmGKB

Interaction Types & Directionality: binder antagonist (inhibitory)

Interaction Info: Mechanism of Interaction Adrenergic receptor alpha-2 antagonist Direct Interaction yes Specific Action of the Ligand Antagonist

PMIDs: 15771415 3419539

Sources: GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 22708686 30155392 12372565

Sources: DrugBank

Interaction Types & Directionality: binder antagonist (inhibitory)

Interaction Info:

PMIDs: 10762339 9265949 15771415 12109911 3419539

Sources: DrugBank

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 23728612 27593622 23229983 11752352

Sources: DrugBank

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Direct Interaction? True Endogenous Drug? False Specific Action of the Ligand Antagonist

PMIDs: None found

Sources: GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18695978

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

n/a

PMIDs:
20709156 15565110

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
18496129

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
28694205

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
28694205

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
12518269

Sources:
NCI

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex

Novel drug target Established target

PMIDs:
17587360 11607047 10446735 8930006 11752352 10446734

Sources:
TEND TdgClinicalTrial

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
11931344 9007838 12523492 14628003 11607047 8930006 19401164 11939713 10793320

Sources:
TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

Direct Interaction? True

PMIDs:
16433010 11271412 10762339 9832994 11752352 14615872

Sources:
TEND TTD DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Serotonin 2a (5-HT2a) receptor antagonist

Direct Interaction yes

Trial Name mirtazapine,Remeron, Remeron SolTab, Reflex

PMIDs:
17067560 15309042 10446738 11607047 11063897 10446735 10446734 10451911

Sources:
TEND TdgClinicalTrial DrugBank GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
16002093

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
22926595

Sources:
PharmGKB

Interaction Types & Directionality:

binder

antagonist (inhibitory)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 antagonist

Direct Interaction yes

Specific Action of the Ligand Antagonist

PMIDs:
15771415 3419539

Sources:
GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

PMIDs:
22708686 30155392 12372565

Sources:
DrugBank

Interaction Types & Directionality:

binder

antagonist (inhibitory)

PMIDs:
10762339 9265949 15771415 12109911 3419539

Sources:
DrugBank

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
23728612 27593622 23229983 11752352

Sources:
DrugBank

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Direct Interaction? True

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
18695978

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

MIRTAZAPINE DrugBank Drug Name

85650-52-8 CAS Number

Apo-mirtazapine Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories adrenergic agents

Alternate Names:

MIRTAZAPINE Primary Drug Name

Drug Info:

Year of Approval 1996

Drug Class antidepressive agents, tricyclic

Drug Info:

Drug Indications antidepressant

Drug Class Small Molecule

FDA Approval approved

Alternate Names:

C29265 NCI drug code

Alternate Names:

MIRTAZAPINE GuideToPharmacology Ligand Name

Alternate Names:

CHEMBL654 ChEMBL Drug ID