MIRTAZAPINE |
REMERON |
REMERON SOLTAB |
ORG-3770 |
ZISPIN |
1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO(2,1-A)PYRIDO(2,3-C)BENZAZEPINE |
6-AZAMIANSERIN |
MEPIRZAPINE |
MIRTAZAPINA |
MIRTAZAPIN |
REMERON® |
MIRTAZAPINUM |
2-METHYL-1,2,3,4,10,14B-HEXAHYDROPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE |
chemidplus:85650-52-8 |
pubchem.compound:4205 |
chemidplus:61337-67-5 |
chembl:CHEMBL654 |
rxcui:15996 |
drugbank:00370 |
FDA Approval | approved |
Drug Class | Small Molecule |
Drug Indications | antidepressant |
Drug Class | antidepressive agents, tricyclic |
Year of Approval | 1996 |
Drug Categories | adrenergic alpha-2 receptor antagonists |
Drug Categories | agents that produce hypertension |
Drug Categories | anti-anxiety agents |
Drug Categories | antidepressive agents, tetracyclic |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors |
Drug Categories | cytochrome p-450 cyp3a4 inhibitors (weak) |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | heterocyclic compounds, fused-ring |
Drug Categories | miscellaneous antidepressants |
Drug Categories | potential qtc-prolonging agents |
Drug Categories | qtc prolonging agents |
Drug Categories | serotonergic drugs shown to increase risk of serotonin syndrome |
Drug Categories | serotonin 5-ht2 receptor antagonists |
Drug Categories | serotonin 5-ht3 receptor antagonists |
Drug Categories | serotonin agents |
Drug Categories | serotonin receptor antagonists |
Drug Categories | tranquilizing agents |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-2 antagonist |
Direct Interaction | yes |
Specific Action of the Ligand | Antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Serotonin 2a (5-HT2a) receptor antagonist |
Direct Interaction | yes |
Trial Name | mirtazapine,Remeron, Remeron SolTab, Reflex |
binder |
antagonist (inhibitory) |
Mechanism of Interaction | Adrenergic receptor alpha-2 antagonist |
Direct Interaction | yes |
Specific Action of the Ligand | Antagonist |
antagonist (inhibitory) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Antagonist |
MIRTAZAPINE | DrugBank Drug Name |
85650-52-8 | CAS Number |
Apo-mirtazapine | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Categories | adrenergic agents |
MIRTAZAPINE | Primary Drug Name |
Year of Approval | 1996 |
Drug Class | antidepressive agents, tricyclic |
Drug Indications | antidepressant |
Drug Class | Small Molecule |
FDA Approval | approved |
C29265 | NCI drug code |
MIRTAZAPINE | GuideToPharmacology Ligand Name |
CHEMBL654 | ChEMBL Drug ID |
D05ZIK | TTD Drug ID |