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MILNACIPRAN Drug Record

  • Summary
  • Interactions
  • Claims
  • MILNACIPRAN chembl:CHEMBL259209 Approved

    Alternate Names:

    MIDALCIPRAN
    MILNACIPRAN
    SAVELLA®
    pubchem.compound:11622909
    chembl:CHEMBL259209

    Drug Info:

    FDA Approval approved
    Drug Class Small Molecule
    Drug Indications for treatment of fibromyalgia syndrome
    Drug Class antidepressive agents
    Year of Approval 2009
    (1 More Sources)

    Publications:

    Kato M et al., 2009, Effect of 5-HT1A gene polymorphisms on antidepressant response in major depressive disorder., Am J Med Genet B Neuropsychiatr Genet
    Leo et al., 2006, Clinical potential of milnacipran, a serotonin and norepinephrine reuptake inhibitor, in pain., Curr Opin Investig Drugs
    Moret et al., 1985, Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug., Neuropharmacology
    Kurose K et al., 2012, Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression., Psychiatry Res
  • MILNACIPRAN   MDGA2

    Interaction Score: 8.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22445761


    Sources:
    PharmGKB

  • MILNACIPRAN   SLC6A2

    Interaction Score: 1.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name Milnacipran
    Novel drug target Established target

    PMIDs:
    16869117 3005901


    Sources:
    TdgClinicalTrial TEND

  • MILNACIPRAN   SLC6A4

    Interaction Score: 0.95

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name Milnacipran
    Novel drug target Established target

    PMIDs:
    16869117 3005901


    Sources:
    TdgClinicalTrial TEND

  • MILNACIPRAN   HTR1A

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18484082


    Sources:
    PharmGKB

  • MILNACIPRAN   ADRA2A

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • TEND: MILNACIPRAN

    • Version: 01-August-2011

    Alternate Names:

    Drug Info:
    Year of Approval 2009
    Drug Class antidepressive agents

    Publications:

  • TdgClinicalTrial: MILNACIPRAN

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications for treatment of fibromyalgia syndrome
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • PharmGKB: milnacipran

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:
    Kato M et al., 2009, Effect of 5-HT1A gene polymorphisms on antidepressant response in major depressive disorder., Am J Med Genet B Neuropsychiatr Genet
    Kurose K et al., 2012, Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression., Psychiatry Res

  • TTD: Milnacipran

    • Version: 2020.06.01

    Alternate Names:
    D09VGC TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL259209

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21