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MIGLITOL Drug Record

  • Summary
  • Interactions
  • Claims
  • MIGLITOL chembl:CHEMBL1561 Approved

    Alternate Names:

    GLYSET
    MIGLITOL
    DIASTABOL
    BAY-M-1099
    MIGLITOLUM
    N-HYDROXYLETHYL-1-DEOXYNOJIRIMYCIN
    GLYSET®
    chembl:CHEMBL1561
    drugbank:00491
    chemidplus:72432-03-2
    pubchem.compound:441314
    rxcui:30009

    Drug Info:

    FDA Approval 1996
    Drug Class small molecule
    Drug Indications Hypoglycemic Agents
    Year of Approval 1996
    Drug Class hypoglycemic agents
    (2 More Sources)

    Publications:

    Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
    Rossi et al., 2006, Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives., FEBS J.
    Fukaya et al., 2009, The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats., Eur. J. Pharmacol.
    Mooradian et al., 1999, Drug therapy of postprandial hyperglycaemia., Drugs
    Kato A et al., 2012, α-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia., J Med Chem
    Hirata et al., 2009, Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats., Horm. Metab. Res.
  • MIGLITOL   MGAM

    Interaction Score: 14.43

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    11752352 16817895 19818342 9951949


    Sources:
    TdgClinicalTrial TEND TTD

  • MIGLITOL   MGA

    Interaction Score: 10.3

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Maltase-glucoamylase inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIGLITOL   GAA

    Interaction Score: 1.52

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Lysosomal alpha-glucosidase inhibitor

    PMIDs:
    23106358 19085811 19818342


    Sources:
    DTC ChemblInteractions

  • TEND: MIGLITOL

    • Version: 01-August-2011

    Alternate Names:
    MIGLITOL Primary Drug Name

    Drug Info:
    Drug Class hypoglycemic agents
    Year of Approval 1996

    Publications:

  • TdgClinicalTrial: MIGLITOL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Hypoglycemic Agents
    Drug Class small molecule
    FDA Approval 1996

    Publications:

  • DTC: MIGLITOL

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1561 ChEMBL Drug ID

    Drug Info:

    Publications:
    Kato A et al., 2012, α-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia., J Med Chem

  • TTD: Miglitol

    • Version: 2020.06.01

    Alternate Names:
    D0D0ZD TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1561

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL1561

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21