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METIPRANOLOL Drug Record

  • Summary
  • Interactions
  • Claims
  • METIPRANOLOL chembl:CHEMBL1291

    Alternate Names:

    VUAB-6453
    METIPRANOLOL
    VUAB6453 (SPOFA)
    OPTIPRANOLOL
    BM-01004
    GLAULINE

    Drug Info:

    FDA Approval 1989
    Drug Class small molecule
    Drug Indications Anti-glaucoma agent
    Drug Indications Antihypertensive Agents
    Drug Indications Anti-Arrhythmia Agents
    Drug Class antihypertensive agents
    Drug Class anti-arrhythmia agents
    Drug Class anti-glaucoma agent
    Year of Approval 1989
    Drug Categories agents causing hyperkalemia
    Drug Categories antiarrhythmic agents
    Drug Categories beta blocking agents and thiazides
    Drug Categories beta blocking agents, non-selective, and thiazides
    Drug Categories cytochrome p-450 cyp2d6 substrates
    Drug Categories cytochrome p-450 substrates
    (2 More Sources)

    Publications:

    Noack, 1986, [Antiglaucomatous effectiveness of beta receptor blockers with special reference to metipranolol]., Klin Monbl Augenheilkd
    Bilcíková et al., 1987, The action of adrenoceptor agonists and antagonists on the guinea pig and dog trachea., Gen. Physiol. Biophys.
    Arai et al., 2003, Beta-adrenergic receptor agonists and antagonists counteract LPS-induced neuronal death in retinal cultures by different mechanisms., Brain Res.
    Drímal et al., 1987, External transport of beta-adrenergic binding sites in ischemic myocardium., Gen. Physiol. Biophys.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
  • METIPRANOLOL   ADRB1

    Interaction Score: 1.35

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    2885244 12967722 2895037 17139284 17016423


    Sources:
    TEND TdgClinicalTrial TTD DrugBank

  • METIPRANOLOL   ADRB2

    Interaction Score: 1.04

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name -

    PMIDs:
    2876128 2885244 12967722 2895037 17139284 17016423


    Sources:
    TEND TdgClinicalTrial DrugBank

  • METIPRANOLOL   AR

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB01214

    • Version: 5.1.7

    Alternate Names:
    METIPRANOLOL DrugBank Drug Name
    22664-55-7 CAS Number
    Betanol Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Categories adrenergic agents

    Publications:
    Noack, 1986, [Antiglaucomatous effectiveness of beta receptor blockers with special reference to metipranolol]., Klin Monbl Augenheilkd
    Bilcíková et al., 1987, The action of adrenoceptor agonists and antagonists on the guinea pig and dog trachea., Gen. Physiol. Biophys.
    Arai et al., 2003, Beta-adrenergic receptor agonists and antagonists counteract LPS-induced neuronal death in retinal cultures by different mechanisms., Brain Res.

  • TEND: METIPRANOLOL

    • Version: 01-August-2011

    Alternate Names:
    METIPRANOLOL Primary Drug Name

    Drug Info:
    Year of Approval 1989
    Drug Class anti-glaucoma agent
    Drug Class anti-arrhythmia agents

    Publications:

  • TdgClinicalTrial: METIPRANOLOL

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Anti-Arrhythmia Agents
    Drug Indications Antihypertensive Agents
    Drug Indications Anti-glaucoma agent

    Publications:

  • TTD: Metipranolol

    • Version: 2020.06.01

    Alternate Names:
    D0L5FY TTD Drug ID

    Drug Info:

    Publications:

  • DTC: METIPRANOLOL

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL1291 ChEMBL Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL1291

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21