DGIdb - METHYLDOPA Drug Record

METHYLDOPA chembl:CHEMBL459 Approved

Alternate Names:

LEDERDOPA
MK-351
METALPHA 500
DOPAMET
MEDOMET
METHYLDOPA HYDRATE
BAYER-1440L
METALPHA 250
ALDOMET
J9.247I
NSC-169916
METHYLDOPA
ALPHA-METHYLDOPA
METHYLDOPA (LEVOROTATORY)
METHYLDOPA SESQUIHYDRATE
NOVOMEDOPA
SEMBRINA
METHYL DOPA
METHOPLAIN
DOPEGYT
L-(-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYL-ALANINE
L-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
ALDORIL D30
NU-MEDOPA TAB 250MG
PRESOLISIN
METHYLDOPA 500 TAB 500MG
NU-MEDOPA
NOVO-MEDOPA TAB 500MG
L(-)-ALPHA-METHYLALANINE
ALPHA-METHYLDOPA (VAN)
BECANTA
(S)-(-)-ALPHA-METHYLDOPA
MEDOPA
METHYLDOPA ANHYDROUS
NOVO-MEDOPA TAB 125MG
2-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE
A-METHYL-L-DOPA
APO METHYLDOPA TAB 125MG
(-)-A-METHYLDOPA
METHYLDOPA 125 TAB 125MG
NU-MEDOPA TAB 125MG
L-ALPHA-METHYLDOPA
ALPHA-METHYL-L-DOPA
ALDORIL 25
AMD
(-)-ALPHA-METHYLDOPA
(-)-METHYLDOPA
L-2-AMINO-2-METHYL-3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
Α-METHYL DOPA
APO METHYLDOPA TAB 500MG
ALDORIL 15
APO METHYLDOPA TAB 250MG
BAYER 1440 L
3-HYDROXY-ALPHA-METHYL-L-TYROSINE
DOPAMETHYPERPAX
L-A-METHYLDOPA
(S)-(-)-A-METHYLDOPA
ALPHA-METHYL-L-3,4-DIHYDROXYPHENYLALANINE
(2S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPANOIC ACID
MEDOPAL
A-METHYLDOPA (VAN)
METHYLDOPATE HCL
ALDOCLOR-150
SEDOMETIL
ALPHAMETHYLDOPA
ALDOCLOR-250
L-(-)-ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)ALANINE
MEDOPREN
L-(-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
METHYL-L-DOPA
L(-)-A-METHYLALANINE
GROSPISK
HYPOLAG
METHYLDOPATE
L-METHYL DOPA
ALDORIL®
NU-MEDOPA TAB 500MG
ALPHA-METHYL DOPA
Α-METHYL-L-DOPA
APO-METHYLDOPA
ALPHA-METHYLDIHYDROXYPHENYLALANINE
ALDOMET®
BAYPRESOL
L-(A-MD)
L(-)-BETA-(3,4-DIHYDROXYPHENYL)-ALPHA-METHYLALANINE
ALDOMETIL
L-(ALPHA-MD)
ALPHA MEDOPA
L-Α-METHYL-3,4-DIHYDROXYPHENYLALANINE
DOPATEC
3,4-DIHYDROXY-2-METHYLPHENYLALANINE (ACD/NAME 4.0)
L-(-)-A-METHYL-A-METHYL-ALDOMIN
HYPERPAX
A-METHYL DOPA
LEVO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
PRESINOL
DOPAMET®
L-(-)-ALPHA-METHYL-ALPHA-METHYL-ALDOMIN
ALDORIL D50
NOVO-MEDOPA TAB 250MG
ANHYDROUS METHYLDOPA
L-ALPHA-METHYL-3,4-DIHYDROXYPHENYLALANINE
METHYLDOPA 250 TAB
A-METHYL-L-3,4-DIHYDROXYPHENYLALANINE
ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE
L-A-METHYL-(3, 4-DIHYDROXYPHENYL)ALANINE
L-ALPHA-METHYL-(3, 4-DIHYDROXYPHENYL)ALANINE
rxcui:6876
chemidplus:555-30-6
chembl:CHEMBL459
drugbank:00968
pubchem.compound:38853
rxcui:1545996

Drug Info:

Year of Approval	1962
Drug Class	antihypertensive agents
Drug Categories	adrenergic alpha-agonists
FDA Approval	1962
Drug Class	small molecule
Drug Indications	Antihypertensive Agents
Drug Categories	catechols
Drug Categories	agents causing muscle toxicity
Drug Categories	antihypertensive agents indicated for hypertension
Drug Categories	aromatic l-amino acid decarboxylase inhibitors
Drug Categories	benzene derivatives
Drug Categories	central alpha-2 adrenergic agonist
Drug Categories	central alpha-agonists
Drug Categories	drugs that are mainly renally excreted
Drug Categories	enzyme inhibitors
Drug Categories	phenols
Drug Groups	investigational
Drug Categories	agents for treatment of hemorrhoids and anal fissures for topical use
Drug Categories	copper absorption inhibitor
Drug Categories	diet, food, and nutrition
Drug Categories	elements
Drug Categories	food
Drug Categories	food and beverages
Drug Categories	growth substances
Drug Categories	laxatives
Drug Categories	metal cations
Drug Categories	metal divalent cations
Drug Categories	metals
Drug Categories	metals, heavy
Drug Categories	micronutrients
Drug Categories	minerals
Drug Categories	physiological phenomena
Drug Categories	replacement preparations
Drug Categories	trace elements
Drug Categories	transition elements
Drug Categories	vasoprotectives
Drug Categories	zinc compounds
Drug Groups	nutraceutical
Drug Categories	acids
Drug Categories	acids, noncarboxylic
Drug Categories	anions
Drug Categories	chlorine compounds
Drug Categories	electrolytes
Drug Categories	ions
Drug Categories	magnetic resonance contrast activity
Drug Categories	paramagnetic contrast agent
Drug Categories	sulfur acids
Drug Categories	sulfur compounds
Drug Categories	sulfuric acids
Drug Categories	cell-mediated immunity
Drug Categories	chromium
Drug Categories	increased histamine release
Drug Categories	standardized chemical allergen

(7 More Sources)

Publications:

Kawasaki, 1997, [Centrally acting sympathetic inhibitors for therapy of patients with hypertension]., Nippon Rinsho
van Zwieten, New central mediators as targets of centrally acting antihypertensive drugs., Clin. Exp. Hypertens.
Head, 1999, Central imidazoline- and alpha 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents., Ann. N. Y. Acad. Sci.
van Zwieten, 1992, Development and trends in the drug treatment of essential hypertension., J Hypertens Suppl
Sica, 2007, Centrally acting antihypertensive agents: an update., J Clin Hypertens (Greenwich)
Velliquette et al., 2003, Contrasting metabolic effects of antihypertensive agents., J. Pharmacol. Exp. Ther.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
SOURKES, 1954, Inhibition of dihydroxy-phenylalanine decarboxylase by derivatives of phenylalanine., Arch. Biochem. Biophys.
Zeqiraj E et al., 2015, Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function., Mol Cell
Wang F et al., 2013, Immobilized metal affinity chromatography and human serum proteomics., J Chromatogr B Analyt Technol Biomed Life Sci
Krishnan U et al., 2006, Novel mutations that enhance or repress the aggregation potential of SOD1., Mol Cell Biochem
Blom AM et al., 2003, Effects of zinc on factor I cofactor activity of C4b-binding protein and factor H., Arch Biochem Biophys
Song C et al., 2013, Crystal structure and functional mechanism of a human antimicrobial membrane channel., Proc Natl Acad Sci U S A
Marx G, 1988, Zinc binding to fibrinogen and fibrin., Arch Biochem Biophys
She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics
Mayer MC et al., 2014, Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization., J Biol Chem
Rasimas JJ et al., 2003, Effects of zinc occupancy on human O6-alkylguanine-DNA alkyltransferase., Biochemistry
Chen Z et al., 2006, Identification of residues critical for Cu2+-mediated inhibition of glycine alpha1 receptors., Neuropharmacology
Martens E et al., 2007, A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains., Biochim Biophys Acta
Gilman JG et al., 1978, The oxygen-linked zinc-binding site of human haemoglobin., Biochem J
Jannetto PJ et al., 2001, Cytochrome b(5) plays a key role in human microsomal chromium(VI) reduction., Toxicology
Wang Y et al., 2007, Structure of the human p53 core domain in the absence of DNA., Acta Crystallogr D Biol Crystallogr
Brodersen DE et al., 1999, Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states., Biochemistry
Stasser JP et al., 2005, Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface., Biochemistry
Hnia K et al., 2007, ZZ domain of dystrophin and utrophin: topology and mapping of a beta-dystroglycan interaction site., Biochem J
Meloni G et al., 2007, Redox silencing of copper in metal-linked neurodegenerative disorders: reaction of Zn7metallothionein-3 with Cu2+ ions., J Biol Chem
Bossak K et al., 2015, Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose)Polymerase 1 (PARP-1) Nuclear Protein., Chem Res Toxicol
Massiah MA et al., 2006, Solution structure of the RBCC/TRIM B-box1 domain of human MID1: B-box with a RING., J Mol Biol
Suzuki H et al., 2008, Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2., Acta Crystallogr Sect F Struct Biol Cryst Commun
Sutherland DE et al., 2012, Single domain metallothioneins: supermetalation of human MT 1a., J Am Chem Soc
Bhuiyan MP et al., 2006, Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases., Bioorg Med Chem
Nestler M et al., 2006, The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22., Mol Cell Biochem
Conner SH et al., 2006, TAK1-binding protein 1 is a pseudophosphatase., Biochem J
Røjkaer R et al., 1997, Partial identification of the Zn2+-binding sites in factor XII and its activation derivatives., Eur J Biochem
Kostic M et al., 2006, Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53., J Mol Biol
Jonsson M et al., 2006, Truncated semenogelin I binds zinc and is cleaved by prostate-specific antigen., J Androl
Soundar S et al., 2006, Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase., J Biol Chem
Vogl T et al., 2006, Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations., Biochim Biophys Acta
Bitto et al., 2007, Structure of aspartoacylase, the brain enzyme impaired in Canavan disease., Proc. Natl. Acad. Sci. U.S.A.
Herga S et al., 2006, Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease., FEBS Lett
Smit V et al., 1992, Human interleukin-3 contains a discontinuous zinc binding domain., Biochem Biophys Res Commun
Nan R et al., 2011, Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration., J Mol Biol
Payne JC et al., 2003, Spectroscopic determination of the binding affinity of zinc to the DNA-binding domains of nuclear hormone receptors., Biochemistry
Golub MS et al., 1996, Aluminum alters iron and manganese uptake and regulation of surface transferrin receptors in primary rat oligodendrocyte cultures., Brain Res
Yang F et al., 2007, High-yield expression in Escherichia coli of soluble human MT2A with native functions., Protein Expr Purif
Palumaa P et al., 2005, Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity., Biochim Biophys Acta
Kothinti R et al., 2010, Zinc finger transcription factor Zn3-Sp1 reactions with Cd2+., Chem Res Toxicol
Koch M et al., 2007, Implications on zinc binding to S100A2., Biochim Biophys Acta
Zakharian TY et al., 2008, Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I., Org Biomol Chem
Eckert R et al., 2003, Zinc ions promote the interaction between heparin and heparin cofactor II., FEBS Lett
Herwald H et al., 2001, Zinc-dependent conformational changes in domain D5 of high molecular mass kininogen modulate contact activation., Eur J Biochem
Gantt SL et al., 2006, Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the identity of the active site metal ion., Biochemistry
Huus K et al., 2006, Chemical and thermal stability of insulin: effects of zinc and ligand binding to the insulin zinc-hexamer., Pharm Res
Ignjatovic T et al., 2002, Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor., J Biol Chem
Lokshin M et al., 2007, p53 and p73 display common and distinct requirements for sequence specific binding to DNA., Nucleic Acids Res

METHYLDOPA KRT6A

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C8A

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA IGHA1

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA DAND5

Interaction Score: 0.72

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
20073493

Sources:
DrugBank
METHYLDOPA HRNR

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA JUP

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA TAB1

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16879102

Sources:
DrugBank
METHYLDOPA IGHM

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA IGLV3-21

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT14

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA IGKV1-17

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT5

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA CYB5A

Interaction Score: 0.72

Interaction Types & Directionality:

substrate

Interaction Info:

PMIDs:
11223168

Sources:
DrugBank
METHYLDOPA FCN3

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT16

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SELENOP

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA HPR

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA JCHAIN

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT10

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SERPINA4

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA APLP2

Interaction Score: 0.36

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
24855651

Sources:
DrugBank
METHYLDOPA ITIH1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C8B

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ITIH4

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA APOA2

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C4BPB

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14522582

Sources:
DrugBank
METHYLDOPA APOA4

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA A1BG

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ASPA

Interaction Score: 0.36

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
17194761 17027983

Sources:
DrugBank
METHYLDOPA IDH3G

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16737955

Sources:
DrugBank
METHYLDOPA SEMG1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16582407

Sources:
DrugBank
METHYLDOPA SIVA1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16683188

Sources:
DrugBank
METHYLDOPA IGKV3-20

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA MT3

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17389590

Sources:
DrugBank
METHYLDOPA CCS

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15736924

Sources:
DrugBank
METHYLDOPA CFB

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C8G

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA APOL1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT1

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA DCD

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23426625

Sources:
DrugBank
METHYLDOPA CFI

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SERPINA3

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA BRCC3

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26344097

Sources:
DrugBank
METHYLDOPA MT2A

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17224279 15698955

Sources:
DrugBank
METHYLDOPA GSN

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA PGLYRP2

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA IGFALS

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA CPN2

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA PDIA3

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA KRT2

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA APOBR

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KRT9

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ITIH2

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ITIH3

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C4BPA

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14522582

Sources:
DrugBank
METHYLDOPA AHSG

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA MT1A

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22242602

Sources:
DrugBank
METHYLDOPA DSP

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA MPG

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16529770

Sources:
DrugBank
METHYLDOPA UTRN

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17009962

Sources:
DrugBank
METHYLDOPA TUFM

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA APLP1

Interaction Score: 0.24

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
24855651

Sources:
DrugBank
METHYLDOPA F13B

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA CPN1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C4B

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14522582

Sources:
DrugBank
METHYLDOPA APCS

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA KNG1

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11168375

Sources:
DrugBank
METHYLDOPA ENO1

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA IDH3A

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16737955

Sources:
DrugBank
METHYLDOPA VTN

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA PSPH

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA F12

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9266689

Sources:
DrugBank
METHYLDOPA PDCD6

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18997320

Sources:
DrugBank
METHYLDOPA PRDX1

Interaction Score: 0.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA C1R

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SERPIND1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12706831

Sources:
DrugBank
METHYLDOPA S100A2

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17239974

Sources:
DrugBank
METHYLDOPA KLKB1

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA S100A9

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17050004

Sources:
DrugBank
METHYLDOPA C1S

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA IL3

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1530641

Sources:
DrugBank
METHYLDOPA S100A8

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17050004

Sources:
DrugBank
METHYLDOPA S100A7

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10026247

Sources:
DrugBank
METHYLDOPA CLU

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA CFH

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21396937

Sources:
DrugBank
METHYLDOPA ORM2

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA GAPDHS

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA EEF1A1

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA ALDOA

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA C1QB

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA PZP

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA DDC

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
13189588

Sources:
DrugBank
METHYLDOPA TP73

Interaction Score: 0.1

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
17170001

Sources:
DrugBank
METHYLDOPA INS

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16969698

Sources:
DrugBank
METHYLDOPA C3

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ARG1

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18802628

Sources:
DrugBank
METHYLDOPA FN1

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C1QC

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SERPINA1

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA TF

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8782865 23896426

Sources:
DrugBank
METHYLDOPA A2M

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA SERPINA6

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA C5

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA PON1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA BDKRB1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11880373

Sources:
DrugBank
METHYLDOPA APOA1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA TTR

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA TPI1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA SOD1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16583143

Sources:
DrugBank
METHYLDOPA P4HB

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA NME1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14534351

Sources:
DrugBank
METHYLDOPA HBA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA FGA

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3178229

Sources:
DrugBank
METHYLDOPA AGT

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA CP

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA MDM2

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16965791

Sources:
DrugBank
METHYLDOPA APOE

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ADRA2A

Interaction Score: 0.03

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

Mechanism of Interaction Adrenergic receptor alpha-2 agonist

PMIDs:
9284427 8743022 10415926 1363322 17485976 14557373 17016423 17139284

Sources:
DrugBank TdgClinicalTrial ChemblInteractions TEND
METHYLDOPA PARP1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25549802

Sources:
DrugBank
METHYLDOPA MMP9

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17137715

Sources:
DrugBank
METHYLDOPA MGMT

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12549918

Sources:
DrugBank
METHYLDOPA SHBG

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA GLRA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16842826

Sources:
DrugBank
METHYLDOPA HBB

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
646791

Sources:
DrugBank
METHYLDOPA APP

Interaction Score: 0.02

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
24855651

Sources:
DrugBank
METHYLDOPA HDAC4

Interaction Score: 0.02

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
16439135

Sources:
DrugBank
METHYLDOPA HDAC8

Interaction Score: 0.01

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
16681389

Sources:
DrugBank
METHYLDOPA HDAC1

Interaction Score: 0.01

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
16439135

Sources:
DrugBank
METHYLDOPA CASP6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA COMT

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
METHYLDOPA F2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank
METHYLDOPA ADRA2B

Interaction Score: 0.0

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
METHYLDOPA RGS4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA BLM

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA ADRA2C

Interaction Score: 0.0

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Adrenergic receptor alpha-2 agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
METHYLDOPA MPHOSPH8

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA ESR1

Interaction Score: 0.0

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
14640689

Sources:
DrugBank
METHYLDOPA RECQL

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA APEX1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA POLB

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA CBX1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA TP53

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17327663

Sources:
DrugBank
METHYLDOPA FEN1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA DRD2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
METHYLDOPA CYP2C9

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
METHYLDOPA POLI

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA CYP2C19

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
METHYLDOPA POLK

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA KDM4E

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA CYP1A2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
METHYLDOPA CYP2D6

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
METHYLDOPA BAZ2B

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA ALDH1A1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA HSD17B10

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA KDM4A

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
METHYLDOPA GMNN

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLDOPA EHMT2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DrugBank: DB00968

Version: 5.1.7

Alternate Names:

555-30-6 CAS Number

Aldomet Drug Brand

Aldomet Ester HCl Inj Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories adrenergic agents

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Sica, 2007, Centrally acting antihypertensive agents: an update., J Clin Hypertens (Greenwich)

DrugBank: DB01593

Version: 5.1.7

Alternate Names:

ZINC DrugBank Drug Name

7440-66-6 CAS Number

24 Multivitamins + Minerals Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups investigational

Publications:

She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics

Chen Z et al., 2006, Identification of residues critical for Cu2+-mediated inhibition of glycine alpha1 receptors., Neuropharmacology

Stasser JP et al., 2005, Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface., Biochemistry

DrugBank: DB06757

Version: 5.1.7

Alternate Names:

MANGANESE DrugBank Drug Name

7439-96-5 CAS Number

24 Multivitamins + Minerals Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Groups nutraceutical

Publications:

Conner SH et al., 2006, TAK1-binding protein 1 is a pseudophosphatase., Biochem J

Soundar S et al., 2006, Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase., J Biol Chem

Golub MS et al., 1996, Aluminum alters iron and manganese uptake and regulation of surface transferrin receptors in primary rat oligodendrocyte cultures., Brain Res

DrugBank: DB11136
- Version: 5.1.7
Alternate Names:

Mineral Support Drug Brand

Mineralex Drug Brand

Mte 4 Inj Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups approved

Drug Categories cell-mediated immunity

Publications:

Jannetto PJ et al., 2001, Cytochrome b(5) plays a key role in human microsomal chromium(VI) reduction., Toxicology
TEND: METHYLDOPA
- Version: 01-August-2011
Alternate Names:

Drug Info:

Drug Class antihypertensive agents

Year of Approval 1962

Publications:
TdgClinicalTrial: METHYLDOPA
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Antihypertensive Agents

Drug Class small molecule

FDA Approval 1962

Publications:
DTC: METHYLDOPA
- Version: 02-September-2020
Alternate Names:

CHEMBL459 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
TTD: Methyldopa
- Version: 2020.06.01
Alternate Names:

D0BA6T TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL459
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL459
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
PharmGKB: Methyldopa
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target
Mechanism of Interaction	Adrenergic receptor alpha-2 agonist

Mechanism of Interaction	Adrenergic receptor alpha-2 agonist
Direct Interaction	yes

555-30-6	CAS Number
Aldomet	Drug Brand
Aldomet Ester HCl Inj	Drug Brand

Drug Type	small molecule
Drug Groups	approved
Drug Categories	adrenergic agents

ZINC	DrugBank Drug Name
7440-66-6	CAS Number
24 Multivitamins + Minerals	Drug Brand

MANGANESE	DrugBank Drug Name
7439-96-5	CAS Number
24 Multivitamins + Minerals	Drug Brand

Mineral Support	Drug Brand
Mineralex	Drug Brand
Mte 4 Inj	Drug Brand

METHYLDOPA Drug Record

METHYLDOPA chembl:CHEMBL459 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: cofactor (activating)

Interaction Info:

PMIDs: 20073493

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16879102

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: substrate

Interaction Info:

PMIDs: 11223168

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

cofactor (activating)

PMIDs:
20073493

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
16879102

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

substrate

PMIDs:
11223168

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

cofactor (activating)

PMIDs:
24855651

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
14522582

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426