• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

METHYLDOPA Drug Record

  • Summary
  • Interactions
  • Claims
  • METHYLDOPA chembl:CHEMBL459 Approved

    Alternate Names:

    LEDERDOPA
    MK-351
    METALPHA 500
    DOPAMET
    MEDOMET
    METHYLDOPA HYDRATE
    BAYER-1440L
    METALPHA 250
    ALDOMET
    J9.247I
    NSC-169916
    METHYLDOPA
    ALPHA-METHYLDOPA
    METHYLDOPA (LEVOROTATORY)
    METHYLDOPA SESQUIHYDRATE
    NOVOMEDOPA
    SEMBRINA
    METHYL DOPA
    METHOPLAIN
    DOPEGYT
    L-(-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYL-ALANINE
    L-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
    ALDORIL D30
    NU-MEDOPA TAB 250MG
    PRESOLISIN
    METHYLDOPA 500 TAB 500MG
    NU-MEDOPA
    NOVO-MEDOPA TAB 500MG
    L(-)-ALPHA-METHYLALANINE
    ALPHA-METHYLDOPA (VAN)
    BECANTA
    (S)-(-)-ALPHA-METHYLDOPA
    MEDOPA
    METHYLDOPA ANHYDROUS
    NOVO-MEDOPA TAB 125MG
    2-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE
    A-METHYL-L-DOPA
    APO METHYLDOPA TAB 125MG
    (-)-A-METHYLDOPA
    METHYLDOPA 125 TAB 125MG
    NU-MEDOPA TAB 125MG
    L-ALPHA-METHYLDOPA
    ALPHA-METHYL-L-DOPA
    ALDORIL 25
    AMD
    (-)-ALPHA-METHYLDOPA
    (-)-METHYLDOPA
    L-2-AMINO-2-METHYL-3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
    Α-METHYL DOPA
    APO METHYLDOPA TAB 500MG
    ALDORIL 15
    APO METHYLDOPA TAB 250MG
    BAYER 1440 L
    3-HYDROXY-ALPHA-METHYL-L-TYROSINE
    DOPAMETHYPERPAX
    L-A-METHYLDOPA
    (S)-(-)-A-METHYLDOPA
    ALPHA-METHYL-L-3,4-DIHYDROXYPHENYLALANINE
    (2S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPANOIC ACID
    MEDOPAL
    A-METHYLDOPA (VAN)
    METHYLDOPATE HCL
    ALDOCLOR-150
    SEDOMETIL
    ALPHAMETHYLDOPA
    ALDOCLOR-250
    L-(-)-ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)ALANINE
    MEDOPREN
    L-(-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
    METHYL-L-DOPA
    L(-)-A-METHYLALANINE
    GROSPISK
    HYPOLAG
    METHYLDOPATE
    L-METHYL DOPA
    ALDORIL®
    NU-MEDOPA TAB 500MG
    ALPHA-METHYL DOPA
    Α-METHYL-L-DOPA
    APO-METHYLDOPA
    ALPHA-METHYLDIHYDROXYPHENYLALANINE
    ALDOMET®
    BAYPRESOL
    L-(A-MD)
    L(-)-BETA-(3,4-DIHYDROXYPHENYL)-ALPHA-METHYLALANINE
    ALDOMETIL
    L-(ALPHA-MD)
    ALPHA MEDOPA
    L-Α-METHYL-3,4-DIHYDROXYPHENYLALANINE
    DOPATEC
    3,4-DIHYDROXY-2-METHYLPHENYLALANINE (ACD/NAME 4.0)
    L-(-)-A-METHYL-A-METHYL-ALDOMIN
    HYPERPAX
    A-METHYL DOPA
    LEVO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE
    PRESINOL
    DOPAMET®
    L-(-)-ALPHA-METHYL-ALPHA-METHYL-ALDOMIN
    ALDORIL D50
    NOVO-MEDOPA TAB 250MG
    ANHYDROUS METHYLDOPA
    L-ALPHA-METHYL-3,4-DIHYDROXYPHENYLALANINE
    METHYLDOPA 250 TAB
    A-METHYL-L-3,4-DIHYDROXYPHENYLALANINE
    ALPHA-METHYL-BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE
    L-A-METHYL-(3, 4-DIHYDROXYPHENYL)ALANINE
    L-ALPHA-METHYL-(3, 4-DIHYDROXYPHENYL)ALANINE
    rxcui:6876
    chemidplus:555-30-6
    chembl:CHEMBL459
    drugbank:00968
    pubchem.compound:38853
    rxcui:1545996

    Drug Info:

    Year of Approval 1962
    Drug Class antihypertensive agents
    Drug Categories adrenergic alpha-agonists
    FDA Approval 1962
    Drug Class small molecule
    Drug Indications Antihypertensive Agents
    Drug Categories catechols
    Drug Categories agents causing muscle toxicity
    Drug Categories antihypertensive agents indicated for hypertension
    Drug Categories aromatic l-amino acid decarboxylase inhibitors
    Drug Categories benzene derivatives
    Drug Categories central alpha-2 adrenergic agonist
    Drug Categories central alpha-agonists
    Drug Categories drugs that are mainly renally excreted
    Drug Categories enzyme inhibitors
    Drug Categories phenols
    Drug Groups investigational
    Drug Categories agents for treatment of hemorrhoids and anal fissures for topical use
    Drug Categories copper absorption inhibitor
    Drug Categories diet, food, and nutrition
    Drug Categories elements
    Drug Categories food
    Drug Categories food and beverages
    Drug Categories growth substances
    Drug Categories laxatives
    Drug Categories metal cations
    Drug Categories metal divalent cations
    Drug Categories metals
    Drug Categories metals, heavy
    Drug Categories micronutrients
    Drug Categories minerals
    Drug Categories physiological phenomena
    Drug Categories replacement preparations
    Drug Categories trace elements
    Drug Categories transition elements
    Drug Categories vasoprotectives
    Drug Categories zinc compounds
    Drug Groups nutraceutical
    Drug Categories acids
    Drug Categories acids, noncarboxylic
    Drug Categories anions
    Drug Categories chlorine compounds
    Drug Categories electrolytes
    Drug Categories ions
    Drug Categories magnetic resonance contrast activity
    Drug Categories paramagnetic contrast agent
    Drug Categories sulfur acids
    Drug Categories sulfur compounds
    Drug Categories sulfuric acids
    Drug Categories cell-mediated immunity
    Drug Categories chromium
    Drug Categories increased histamine release
    Drug Categories standardized chemical allergen
    (7 More Sources)

    Publications:

    Kawasaki, 1997, [Centrally acting sympathetic inhibitors for therapy of patients with hypertension]., Nippon Rinsho
    van Zwieten, New central mediators as targets of centrally acting antihypertensive drugs., Clin. Exp. Hypertens.
    Head, 1999, Central imidazoline- and alpha 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents., Ann. N. Y. Acad. Sci.
    van Zwieten, 1992, Development and trends in the drug treatment of essential hypertension., J Hypertens Suppl
    Sica, 2007, Centrally acting antihypertensive agents: an update., J Clin Hypertens (Greenwich)
    Velliquette et al., 2003, Contrasting metabolic effects of antihypertensive agents., J. Pharmacol. Exp. Ther.
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
    SOURKES, 1954, Inhibition of dihydroxy-phenylalanine decarboxylase by derivatives of phenylalanine., Arch. Biochem. Biophys.
    Zeqiraj E et al., 2015, Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function., Mol Cell
    Wang F et al., 2013, Immobilized metal affinity chromatography and human serum proteomics., J Chromatogr B Analyt Technol Biomed Life Sci
    Krishnan U et al., 2006, Novel mutations that enhance or repress the aggregation potential of SOD1., Mol Cell Biochem
    Blom AM et al., 2003, Effects of zinc on factor I cofactor activity of C4b-binding protein and factor H., Arch Biochem Biophys
    Song C et al., 2013, Crystal structure and functional mechanism of a human antimicrobial membrane channel., Proc Natl Acad Sci U S A
    Marx G, 1988, Zinc binding to fibrinogen and fibrin., Arch Biochem Biophys
    She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics
    Mayer MC et al., 2014, Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization., J Biol Chem
    Rasimas JJ et al., 2003, Effects of zinc occupancy on human O6-alkylguanine-DNA alkyltransferase., Biochemistry
    Chen Z et al., 2006, Identification of residues critical for Cu2+-mediated inhibition of glycine alpha1 receptors., Neuropharmacology
    Martens E et al., 2007, A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains., Biochim Biophys Acta
    Gilman JG et al., 1978, The oxygen-linked zinc-binding site of human haemoglobin., Biochem J
    Jannetto PJ et al., 2001, Cytochrome b(5) plays a key role in human microsomal chromium(VI) reduction., Toxicology
    Wang Y et al., 2007, Structure of the human p53 core domain in the absence of DNA., Acta Crystallogr D Biol Crystallogr
    Brodersen DE et al., 1999, Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loaded and Zn2+-free states., Biochemistry
    Stasser JP et al., 2005, Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface., Biochemistry
    Hnia K et al., 2007, ZZ domain of dystrophin and utrophin: topology and mapping of a beta-dystroglycan interaction site., Biochem J
    Meloni G et al., 2007, Redox silencing of copper in metal-linked neurodegenerative disorders: reaction of Zn7metallothionein-3 with Cu2+ ions., J Biol Chem
    Bossak K et al., 2015, Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose)Polymerase 1 (PARP-1) Nuclear Protein., Chem Res Toxicol
    Massiah MA et al., 2006, Solution structure of the RBCC/TRIM B-box1 domain of human MID1: B-box with a RING., J Mol Biol
    Suzuki H et al., 2008, Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2., Acta Crystallogr Sect F Struct Biol Cryst Commun
    Sutherland DE et al., 2012, Single domain metallothioneins: supermetalation of human MT 1a., J Am Chem Soc
    Bhuiyan MP et al., 2006, Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases., Bioorg Med Chem
    Nestler M et al., 2006, The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22., Mol Cell Biochem
    Conner SH et al., 2006, TAK1-binding protein 1 is a pseudophosphatase., Biochem J
    Røjkaer R et al., 1997, Partial identification of the Zn2+-binding sites in factor XII and its activation derivatives., Eur J Biochem
    Kostic M et al., 2006, Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53., J Mol Biol
    Jonsson M et al., 2006, Truncated semenogelin I binds zinc and is cleaved by prostate-specific antigen., J Androl
    Soundar S et al., 2006, Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase., J Biol Chem
    Vogl T et al., 2006, Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations., Biochim Biophys Acta
    Bitto et al., 2007, Structure of aspartoacylase, the brain enzyme impaired in Canavan disease., Proc. Natl. Acad. Sci. U.S.A.
    Herga S et al., 2006, Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease., FEBS Lett
    Smit V et al., 1992, Human interleukin-3 contains a discontinuous zinc binding domain., Biochem Biophys Res Commun
    Nan R et al., 2011, Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration., J Mol Biol
    Payne JC et al., 2003, Spectroscopic determination of the binding affinity of zinc to the DNA-binding domains of nuclear hormone receptors., Biochemistry
    Golub MS et al., 1996, Aluminum alters iron and manganese uptake and regulation of surface transferrin receptors in primary rat oligodendrocyte cultures., Brain Res
    Yang F et al., 2007, High-yield expression in Escherichia coli of soluble human MT2A with native functions., Protein Expr Purif
    Palumaa P et al., 2005, Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity., Biochim Biophys Acta
    Kothinti R et al., 2010, Zinc finger transcription factor Zn3-Sp1 reactions with Cd2+., Chem Res Toxicol
    Koch M et al., 2007, Implications on zinc binding to S100A2., Biochim Biophys Acta
    Zakharian TY et al., 2008, Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I., Org Biomol Chem
    Eckert R et al., 2003, Zinc ions promote the interaction between heparin and heparin cofactor II., FEBS Lett
    Herwald H et al., 2001, Zinc-dependent conformational changes in domain D5 of high molecular mass kininogen modulate contact activation., Eur J Biochem
    Gantt SL et al., 2006, Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the identity of the active site metal ion., Biochemistry
    Huus K et al., 2006, Chemical and thermal stability of insulin: effects of zinc and ligand binding to the insulin zinc-hexamer., Pharm Res
    Ignjatovic T et al., 2002, Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor., J Biol Chem
    Lokshin M et al., 2007, p53 and p73 display common and distinct requirements for sequence specific binding to DNA., Nucleic Acids Res
  • METHYLDOPA   KRT6A

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C8A

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   IGHA1

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   DAND5

    Interaction Score: 0.72

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    20073493


    Sources:
    DrugBank

  • METHYLDOPA   HRNR

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   JUP

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   TAB1

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16879102


    Sources:
    DrugBank

  • METHYLDOPA   IGHM

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   IGLV3-21

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT14

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   IGKV1-17

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT5

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   CYB5A

    Interaction Score: 0.72

    Interaction Types & Directionality:
    substrate

    Interaction Info:

    PMIDs:
    11223168


    Sources:
    DrugBank

  • METHYLDOPA   FCN3

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT16

    Interaction Score: 0.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SELENOP

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   HPR

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   JCHAIN

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT10

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SERPINA4

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   APLP2

    Interaction Score: 0.36

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    24855651


    Sources:
    DrugBank

  • METHYLDOPA   ITIH1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C8B

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ITIH4

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   APOA2

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C4BPB

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14522582


    Sources:
    DrugBank

  • METHYLDOPA   APOA4

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   A1BG

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ASPA

    Interaction Score: 0.36

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    17194761 17027983


    Sources:
    DrugBank

  • METHYLDOPA   IDH3G

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16737955


    Sources:
    DrugBank

  • METHYLDOPA   SEMG1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16582407


    Sources:
    DrugBank

  • METHYLDOPA   SIVA1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16683188


    Sources:
    DrugBank

  • METHYLDOPA   IGKV3-20

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   MT3

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17389590


    Sources:
    DrugBank

  • METHYLDOPA   CCS

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15736924


    Sources:
    DrugBank

  • METHYLDOPA   CFB

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C8G

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   APOL1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT1

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   DCD

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23426625


    Sources:
    DrugBank

  • METHYLDOPA   CFI

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SERPINA3

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   BRCC3

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26344097


    Sources:
    DrugBank

  • METHYLDOPA   MT2A

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17224279 15698955


    Sources:
    DrugBank

  • METHYLDOPA   GSN

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   PGLYRP2

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   IGFALS

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   CPN2

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   PDIA3

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   KRT2

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   APOBR

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KRT9

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ITIH2

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ITIH3

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C4BPA

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14522582


    Sources:
    DrugBank

  • METHYLDOPA   AHSG

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   MT1A

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22242602


    Sources:
    DrugBank

  • METHYLDOPA   DSP

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   MPG

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16529770


    Sources:
    DrugBank

  • METHYLDOPA   UTRN

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17009962


    Sources:
    DrugBank

  • METHYLDOPA   TUFM

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   APLP1

    Interaction Score: 0.24

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    24855651


    Sources:
    DrugBank

  • METHYLDOPA   F13B

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   CPN1

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C4B

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14522582


    Sources:
    DrugBank

  • METHYLDOPA   APCS

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   KNG1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11168375


    Sources:
    DrugBank

  • METHYLDOPA   ENO1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   IDH3A

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16737955


    Sources:
    DrugBank

  • METHYLDOPA   VTN

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   PSPH

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   F12

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9266689


    Sources:
    DrugBank

  • METHYLDOPA   PDCD6

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18997320


    Sources:
    DrugBank

  • METHYLDOPA   PRDX1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   C1R

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SERPIND1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12706831


    Sources:
    DrugBank

  • METHYLDOPA   S100A2

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17239974


    Sources:
    DrugBank

  • METHYLDOPA   KLKB1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   S100A9

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17050004


    Sources:
    DrugBank

  • METHYLDOPA   C1S

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   IL3

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1530641


    Sources:
    DrugBank

  • METHYLDOPA   S100A8

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17050004


    Sources:
    DrugBank

  • METHYLDOPA   S100A7

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10026247


    Sources:
    DrugBank

  • METHYLDOPA   CLU

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   CFH

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21396937


    Sources:
    DrugBank

  • METHYLDOPA   ORM2

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   GAPDHS

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   EEF1A1

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   ALDOA

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   C1QB

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   PZP

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   DDC

    Interaction Score: 0.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    13189588


    Sources:
    DrugBank

  • METHYLDOPA   TP73

    Interaction Score: 0.1

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    17170001


    Sources:
    DrugBank

  • METHYLDOPA   INS

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16969698


    Sources:
    DrugBank

  • METHYLDOPA   C3

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ARG1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18802628


    Sources:
    DrugBank

  • METHYLDOPA   FN1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C1QC

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SERPINA1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   TF

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8782865 23896426


    Sources:
    DrugBank

  • METHYLDOPA   A2M

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   SERPINA6

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   C5

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   PON1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   BDKRB1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11880373


    Sources:
    DrugBank

  • METHYLDOPA   APOA1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   TTR

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   TPI1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   SOD1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16583143


    Sources:
    DrugBank

  • METHYLDOPA   P4HB

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   NME1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14534351


    Sources:
    DrugBank

  • METHYLDOPA   HBA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   FGA

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3178229


    Sources:
    DrugBank

  • METHYLDOPA   AGT

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   CP

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   MDM2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16965791


    Sources:
    DrugBank

  • METHYLDOPA   APOE

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ADRA2A

    Interaction Score: 0.03

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name -
    Novel drug target Established target
    Mechanism of Interaction Adrenergic receptor alpha-2 agonist

    PMIDs:
    9284427 8743022 10415926 1363322 17485976 14557373 17016423 17139284


    Sources:
    DrugBank TdgClinicalTrial ChemblInteractions TEND

  • METHYLDOPA   PARP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25549802


    Sources:
    DrugBank

  • METHYLDOPA   MMP9

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17137715


    Sources:
    DrugBank

  • METHYLDOPA   MGMT

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12549918


    Sources:
    DrugBank

  • METHYLDOPA   SHBG

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   GLRA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16842826


    Sources:
    DrugBank

  • METHYLDOPA   HBB

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    646791


    Sources:
    DrugBank

  • METHYLDOPA   APP

    Interaction Score: 0.02

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    24855651


    Sources:
    DrugBank

  • METHYLDOPA   HDAC4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    16439135


    Sources:
    DrugBank

  • METHYLDOPA   HDAC8

    Interaction Score: 0.01

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    16681389


    Sources:
    DrugBank

  • METHYLDOPA   HDAC1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    16439135


    Sources:
    DrugBank

  • METHYLDOPA   CASP6

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   COMT

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • METHYLDOPA   F2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23896426


    Sources:
    DrugBank

  • METHYLDOPA   ADRA2B

    Interaction Score: 0.0

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor alpha-2 agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • METHYLDOPA   RGS4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   BLM

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   ADRA2C

    Interaction Score: 0.0

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Adrenergic receptor alpha-2 agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • METHYLDOPA   MPHOSPH8

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   ESR1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    cofactor (activating)

    Interaction Info:

    PMIDs:
    14640689


    Sources:
    DrugBank

  • METHYLDOPA   RECQL

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   APEX1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   POLB

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   CBX1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   TP53

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17327663


    Sources:
    DrugBank

  • METHYLDOPA   FEN1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   DRD2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • METHYLDOPA   CYP2C9

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • METHYLDOPA   POLI

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   CYP2C19

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • METHYLDOPA   POLK

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   KDM4E

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   CYP1A2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • METHYLDOPA   CYP2D6

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • METHYLDOPA   BAZ2B

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   ALDH1A1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   HSD17B10

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   KDM4A

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22931300


    Sources:
    DTC

  • METHYLDOPA   GMNN

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   EHMT2

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DrugBank: DB00968

    • Version: 5.1.7

    Alternate Names:
    555-30-6 CAS Number
    Aldomet Drug Brand
    Aldomet Ester HCl Inj Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Categories adrenergic agents

    Publications:
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Sica, 2007, Centrally acting antihypertensive agents: an update., J Clin Hypertens (Greenwich)

  • DrugBank: DB01593

    • Version: 5.1.7

    Alternate Names:
    ZINC DrugBank Drug Name
    7440-66-6 CAS Number
    24 Multivitamins + Minerals Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups investigational

    Publications:
    She YM et al., 2003, Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry., Mol Cell Proteomics
    Chen Z et al., 2006, Identification of residues critical for Cu2+-mediated inhibition of glycine alpha1 receptors., Neuropharmacology
    Stasser JP et al., 2005, Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface., Biochemistry

  • DrugBank: DB06757

    • Version: 5.1.7

    Alternate Names:
    MANGANESE DrugBank Drug Name
    7439-96-5 CAS Number
    24 Multivitamins + Minerals Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups nutraceutical

    Publications:
    Conner SH et al., 2006, TAK1-binding protein 1 is a pseudophosphatase., Biochem J
    Soundar S et al., 2006, Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase., J Biol Chem
    Golub MS et al., 1996, Aluminum alters iron and manganese uptake and regulation of surface transferrin receptors in primary rat oligodendrocyte cultures., Brain Res

  • DrugBank: DB11136

    • Version: 5.1.7

    Alternate Names:
    Mineral Support Drug Brand
    Mineralex Drug Brand
    Mte 4 Inj Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Categories cell-mediated immunity

    Publications:
    Jannetto PJ et al., 2001, Cytochrome b(5) plays a key role in human microsomal chromium(VI) reduction., Toxicology

  • TEND: METHYLDOPA

    • Version: 01-August-2011

    Alternate Names:

    Drug Info:
    Drug Class antihypertensive agents
    Year of Approval 1962

    Publications:

  • TdgClinicalTrial: METHYLDOPA

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications Antihypertensive Agents
    Drug Class small molecule
    FDA Approval 1962

    Publications:

  • DTC: METHYLDOPA

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL459 ChEMBL Drug ID

    Drug Info:

    Publications:
    Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

  • TTD: Methyldopa

    • Version: 2020.06.01

    Alternate Names:
    D0BA6T TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL459

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL459

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications:

  • PharmGKB: Methyldopa

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21