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METHOXSALEN Drug Record

  • Summary
  • Interactions
  • Claims
  • METHOXSALEN chembl:CHEMBL416 Approved

    Alternate Names:

    METHOXSALEN
    MELADININE
    OXSORALEN-ULTRA
    PUVASORALEN-8
    OXSORALEN
    DELTASORALEN
    NSC-45923
    XANTHOTOXIN
    8-MOP
    UVADEX
    SM-88 COMPONENT METHOXSALEN
    8-METHOXYPSORALEN
    8-METHOXYFURANOCOUMARIN
    ULTRA MOP
    8-MP
    O-METHYLXANTHOTOXOL
    MÉTHOXSALÈNE
    XANTHOTOXINE
    AMMOIDIN
    6-HYDROXY-7-METHOXY-5-BENZOFURANACRYLIC ACID DELTA-LACTONE
    9-METHOXY-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
    8-METHOXY-2',3',6,7-FUROCOUMARIN
    8-METHOXY-[FURANO-3'.2':6.7-COUMARIN]
    ZANTHOTOXIN
    XANTHOXIN
    8-METHOXY-4',5':6,7-FUROCOUMARIN
    MELOXINE
    6,7-FUROCOUMARIN
    METHOXALEN
    drugbank:00553
    rxcui:6854
    chembl:CHEMBL416
    pubchem.compound:4114
    chemidplus:298-81-7

    Drug Info:

    (1 More Sources)

    Publications:

    Yang et al., 2007, Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor., Toxicol. Sci.
    Cappellini et al., 2005, Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation., Apoptosis
    Amano et al., 1998, Inhibition of substance-P-induced histamine release from rat peritoneal mast cells by 8-methoxypsoralen plus long-wave ultraviolet light irradiation: decreased intracellular calcium as a possible mechanism., Int. Arch. Allergy Immunol.
    Fedorova et al., 1987, [Repair of plasmid DNA treated with 8-methoxypsoralen and long-wave UV light (lambda=365 nm) in wild type and mutant rad2 cells of Saccharomyces cerevisiae]., Genetika
  • METHOXSALEN   TAC1

    Interaction Score: 0.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9430496


    Sources:
    NCI

  • METHOXSALEN   CYP2A6

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • METHOXSALEN   MAPK14

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15711930


    Sources:
    NCI

  • METHOXSALEN   FEN1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3319774


    Sources:
    NCI

  • METHOXSALEN   ESR1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHOXSALEN   CYP3A4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17003103


    Sources:
    DTC NCI

  • METHOXSALEN   CYP1A2

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHOXSALEN   CYP2D6

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NCI: 8-MOP

    • Version: 14-September-2017

    Alternate Names:
    C643 NCI drug code

    Drug Info:

    Publications:
    Yang et al., 2007, Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor., Toxicol. Sci.
    Fedorova et al., 1987, [Repair of plasmid DNA treated with 8-methoxypsoralen and long-wave UV light (lambda=365 nm) in wild type and mutant rad2 cells of Saccharomyces cerevisiae]., Genetika
    Amano et al., 1998, Inhibition of substance-P-induced histamine release from rat peritoneal mast cells by 8-methoxypsoralen plus long-wave ultraviolet light irradiation: decreased intracellular calcium as a possible mechanism., Int. Arch. Allergy Immunol.

  • NCI: 8-METHOXYPSORALEN

    • Version: 14-September-2017

    Alternate Names:
    C643 NCI drug code

    Drug Info:

    Publications:
    Cappellini et al., 2005, Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation., Apoptosis

  • DTC: METHOXSALEN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL416 ChEMBL Drug ID

    Drug Info:

    Publications:

  • TTD: Methoxsalen

    • Version: 2020.06.01

    Alternate Names:
    D08SKH TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL416

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21