DGIdb - LYSERGIDE Drug Record

LYSERGIDE chembl:CHEMBL263881

Alternate Names:

LYSERGIC ACID DIETHYLAMIDE
LSD
LYSERGIC ACID DIETHYLAMIDE TARTRATE CI
LYSERGIDE
9,10-DIDEHYDRO-N,N-DIETHYL-6-METHYLERGOLINE-8B-CARBOXAMIDE
D-LSD-25
D-LYSERGIC ACID DIETHYLAMIDE
LYSERGAMID
DEXTROLYSERGIC ACID DIETHYLAMIDE
N,N-DIETHYL-6-METHYL-9,10-DIDEHYDROERGOLINE-8-CARBOXAMIDE
LYSERGAMIDE
LYSERGIC ACID AMIDE
LYSERGIC ACID DIETHYLAMIDE-25
LSD-25
N,N-DIETHYL-(+)-LYSERGAMIDE
LYSERGIDUM
N,N-DIETHYLLYSERGAMIDE
LSD 25
N,N-DIETHYL-D-LYSERGAMIDE
LYSERGIC SOURSTUFF DIETHYLAMIDE
LYSERGAURE DIETHYLAMID
(+)-LSD
D-LYSERGIC ACID DETHYLAMIDE
(+)-LYSERGIC CID DIETHYLAMIDE
D-LSD
DIETHYLAMID KYSELINY LYSERGOVE
D-LYSERGIC ACID N,N-DIETHYLAMIDE
pubchem.compound:5761
chembl:CHEMBL263881
drugbank:04829
chemidplus:50-37-3

Drug Info:

Drug Categories	hallucinogens
Drug Groups	investigational
Drug Categories	agents that produce hypertension
Drug Categories	antidepressive agents
Drug Categories	central nervous system depressants
Drug Categories	cytochrome p-450 cyp2d6 substrates
Drug Categories	cytochrome p-450 cyp3a substrates
Drug Categories	cytochrome p-450 cyp3a4 substrates
Drug Categories	cytochrome p-450 substrates
Drug Categories	ergot alkaloids and derivatives
Drug Categories	heterocyclic compounds, fused-ring
Drug Categories	serotonergic drugs shown to increase risk of serotonin syndrome
Drug Categories	serotonin 5-ht2 receptor agonists
Drug Categories	serotonin receptor antagonists

(0 More Sources)

Publications:

AGHAJANIAN et al., PERSISTENCE OF LYSERGIC ACID DIETHYLAMIDE IN THE PLASMA OF HUMAN SUBJECTS., Clin. Pharmacol. Ther.
Blanpain et al., 2003, Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension., Cardiovasc. Res.
van Loevezijn A et al., 2011, N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features., J Med Chem

LYSERGIDE HTR6

Interaction Score: 0.67

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
21866910

Sources:
DrugBank GuideToPharmacology
LYSERGIDE HTR2B

Interaction Score: 0.42

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Biased agonist

PMIDs:
14659797

Sources:
DrugBank GuideToPharmacology
LYSERGIDE HTR1A

Interaction Score: 0.23

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
14209776

Sources:
DrugBank GuideToPharmacology
LYSERGIDE HTR2C

Interaction Score: 0.09

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
LYSERGIDE HTR2A

Interaction Score: 0.06

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

DrugBank: DB04829

Version: 5.1.7

Alternate Names:

LYSERGIC ACID DIETHYLAMIDE DrugBank Drug Name

50-37-3 CAS Number

Delysid Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups illicit

Drug Groups investigational

Publications:

Blanpain et al., 2003, Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension., Cardiovasc. Res.

AGHAJANIAN et al., PERSISTENCE OF LYSERGIC ACID DIETHYLAMIDE IN THE PLASMA OF HUMAN SUBJECTS., Clin. Pharmacol. Ther.

van Loevezijn A et al., 2011, N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features., J Med Chem

GuideToPharmacology: 135650536
- Version: 29-September-2020
Alternate Names:

LYSERGIDE GuideToPharmacology Ligand Name

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL263881
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Specific Action of the Ligand	Full agonist
Endogenous Drug?	False

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Biased agonist

LYSERGIC ACID DIETHYLAMIDE	DrugBank Drug Name
50-37-3	CAS Number
Delysid	Drug Brand

Drug Type	small molecule
Drug Groups	illicit
Drug Groups	investigational

LYSERGIDE Drug Record

LYSERGIDE chembl:CHEMBL263881

Alternate Names:

Drug Info:

Publications:

LYSERGIDE HTR6

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: 21866910

Sources: DrugBank GuideToPharmacology

LYSERGIDE HTR2B

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Biased agonist

PMIDs: 14659797

Sources: DrugBank GuideToPharmacology

LYSERGIDE HTR1A

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: 14209776

Sources: DrugBank GuideToPharmacology

LYSERGIDE HTR2C

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

LYSERGIDE HTR2A

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

DrugBank: DB04829

Alternate Names: LYSERGIC ACID DIETHYLAMIDE DrugBank Drug Name 50-37-3 CAS Number Delysid Drug Brand

Drug Info: Drug Type small molecule Drug Groups illicit Drug Groups investigational

GuideToPharmacology: 135650536

Alternate Names: LYSERGIDE GuideToPharmacology Ligand Name

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL263881

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
21866910

Sources:
DrugBank GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Biased agonist

PMIDs:
14659797

Sources:
DrugBank GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
14209776

Sources:
DrugBank GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Alternate Names:

LYSERGIC ACID DIETHYLAMIDE DrugBank Drug Name

50-37-3 CAS Number

Delysid Drug Brand

Drug Info:

Drug Type small molecule

Drug Groups illicit

Drug Groups investigational

Alternate Names:

LYSERGIDE GuideToPharmacology Ligand Name