• LOMITAPIDE chembl:CHEMBL354541 Approved

    Alternate Names:

    AEGR-733
    LOJUXTA
    LOMITAPIDE
    BMS-201038-01
    BMS-201038
    BMS 201038
    AEGR 733
    LOJUXTA®
    JUXTAPID®
    pubchem.compound:9853053
    chemidplus:182431-12-5
    drugbank:08827
    chembl:CHEMBL354541
    rxcui:1364479

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications anticholesterolaemic agent
    Drug Groups investigational
    Drug Categories cytochrome p-450 cyp3a substrates
    Drug Categories cytochrome p-450 cyp3a4 inhibitors
    Drug Categories cytochrome p-450 cyp3a4 substrates (strength unknown)
    Drug Categories cytochrome p-450 enzyme inhibitors
    Drug Categories cytochrome p-450 substrates
    Drug Categories hepatotoxic agents
    Drug Categories heterocyclic compounds, fused-ring
    Drug Categories hypolipidemic agents
    Drug Categories hypolipidemic agents indicated for hyperlipidemia
    Drug Categories microsomal triglyceride transfer protein inhibitor
    Drug Categories microsomal triglyceride transfer protein inhibitors
    Drug Categories miscellaneous antilipemic agents
    Drug Categories p-glycoprotein inhibitors
    (0 More Sources)

    Publications:

  • Interaction Score: 3.16

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name lomitapide , AEGR-733, BMS-201038
    Novel drug target Novel Target

    PMIDs:
    None found


  • Interaction Score: 2.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Interaction Score: 0.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Interaction Score: 0.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

    • Version: 5.1.7

    Alternate Names:
    LOMITAPIDE DrugBank Drug Name
    182431-12-5 CAS Number
    Juxtapid Drug Brand

    Drug Info:
    Drug Type small molecule
    Drug Groups approved
    Drug Groups investigational

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications anticholesterolaemic agent
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

    • Version: 18-August-2020

    Alternate Names:

    Drug Info:

    Publications: