• LINIFANIB chembl:CHEMBL223360 Antineoplastic

    Alternate Names:

    ABT-869
    AL-39324
    RG-3635
    A-741439
    LINIFANIB

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antineoplastic agent
    Drug Class Kinase Inhibitors
    Drug Categories heterocyclic compounds, fused-ring
    (5 More Sources)

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  • Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

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    inhibitor (inhibitory)

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    Mechanism of Interaction Vascular endothelial growth factor receptor inhibitor
    Direct Interaction yes
    Trial Name ABT-869, Linifanib

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    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Platelet-derived growth factor receptor inhibitor
    Direct Interaction yes

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    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

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    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase receptor FLT3 inhibitor
    Direct Interaction yes
    Trial Name ABT-869, Linifanib

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    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

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    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

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    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

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  • Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Macrophage colony stimulating factor receptor inhibitor
    Direct Interaction? False

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  • Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

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    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name ABT-869, Linifanib
    Specific Action of the Ligand Inhibition

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  • Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name ABT-869, Linifanib
    Novel drug target Established target
    Specific Action of the Ligand Inhibition

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    • Version: 20-Jun-2017

    Alternate Names:
    ABT-869 Development Name
    LINIFANIB Generic Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

    • Version: 5.1.7

    Alternate Names:
    ABT-869 DrugBank Drug Name

    Drug Info:
    Drug Type small molecule
    Drug Groups investigational
    Drug Categories benzene derivatives

    Publications:

    • Version: January-2014

    Alternate Names:

    Drug Info:
    FDA Approval not approved
    Drug Indications antineoplastic agent
    Drug Class Small molecule

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    • Version: 12-May-2016

    Alternate Names:
    LINIFANIB Primary Drug Name
    LINIFANIB Drug Generic Name
    ABT-869 Drug Synonym

    Drug Info:

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    • Version: 02-September-2020

    Alternate Names:
    CHEMBL223360 ChEMBL Drug ID

    Drug Info:

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    • Version: 2020.06.01

    Alternate Names:
    D0M9QZ TTD Drug ID

    Drug Info:

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    • Version: 29-September-2020

    Alternate Names:
    LINIFANIB GuideToPharmacology Ligand Name

    Drug Info:

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    • Version: ChEMBL_27

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    • Version: chembl_23

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