ALGRX 3268 |
XYLOCAINE |
VAGISIL |
LIDOPEN |
LIGNOCAINE |
OCTOCAINE |
LIDOCAINE |
ORAQIX |
NSC-40030 |
XYLODASE |
LIGNOCAINE HCL |
IONTOCAINE |
LMX 4 |
LIDOCATON |
ANESTACON |
DENTIPATCH |
ZTLIDO |
ALGRX-3268 |
ALPHACAINE |
XYLOTOX |
EMBOLEX |
LIGNOSTAB |
LIDODERM |
Α-DIETHYLAMINO-2,6-DIMETHYLACETANILIDE |
2-(DIETHYLAMINO)-N-(2,6-DIMETHYLPHENYL)ACETAMIDE |
ALPHA-DIETHYLAMINO-2,6-DIMETHYLACETANILIDE |
2-(DIETHYLAMINO)-2',6'-ACETOXYLIDIDE |
XYLOCAINE® |
chemidplus:137-58-6 |
rxcui:6387 |
pubchem.compound:3676 |
chembl:CHEMBL79 |
drugbank:00281 |
Drug Indications | for treatment of pelvic pain of bladder origin and interstitital cystitis |
Drug Indications | for treatment of premature ejaculation |
Drug Indications | anestethic |
FDA Approval | approved |
Drug Class | Small Molecule |
Drug Indications | anesthetic |
Drug Class | anesthetics, local |
Drug Class | anti-arrhythmia agents |
Year of Approval | approved before 1982 |
Drug Categories | agents for treatment of hemorrhoids and anal fissures for topical use |
Drug Categories | agents that reduce seizure threshold |
Drug Categories | amide local anesthetic |
Drug Categories | amines |
Drug Categories | analgesics and anesthetics |
Drug Categories | anesthetics for topical use |
Drug Categories | aniline compounds |
Drug Categories | antiarrhythmic agents |
Drug Categories | antiarrhythmics, class i |
Drug Categories | antiarrhythmics, class ib |
Drug Categories | antipruritics and local anesthetics |
Drug Categories | antipruritics, incl. antihistamines, anesthetics, etc. |
Drug Categories | cardiac therapy |
Drug Categories | cytochrome p-450 cyp2c18 substrates |
Drug Categories | cytochrome p-450 cyp2d6 inhibitors (strength unknown) |
Drug Categories | cytochrome p-450 cyp3a substrates |
Drug Categories | cytochrome p-450 cyp3a5 substrates |
Drug Categories | cytochrome p-450 cyp3a7 substrates |
Drug Categories | cytochrome p-450 enzyme inhibitors |
Drug Categories | cytochrome p-450 substrates |
Drug Categories | dermatologicals |
Drug Categories | local anesthesia |
Drug Categories | neuraxial anesthetics |
Drug Categories | ophthalmologicals |
Drug Categories | otologicals |
Drug Categories | p-glycoprotein inhibitors |
Drug Categories | throat preparations |
Drug Categories | vasoprotectives |
blocker (inhibitory) |
inhibitor (inhibitory) |
Specific Action of the Ligand | Pore blocker |
Endogenous Drug? | False |
Direct Interaction? | True |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
Trial Name | ALGRX 3268,Zingo |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | ALGRX 3268,Zingo |
Novel drug target | Established target |
Trial Name | lidocaine hydrochloride, piroxicam, AK1015,Akten |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | PSD502, lidocaine + prilocaine |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Combination therapy | Lidocaine,Prilocaine |
Combination therapy | Lidocaine,Tetracaine |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
LIDOCAINE | DrugBank Drug Name |
137-58-6 | CAS Number |
0.4% Lidocaine Hydrochloride and 5% Dextrose Injection | Drug Brand |
Drug Type | small molecule |
Drug Groups | approved |
Drug Groups | vet_approved |
LIDOCAINE | Primary Drug Name |
Year of Approval | approved before 1982 |
Drug Class | anti-arrhythmia agents |
Drug Class | anesthetics, local |
Drug Indications | anesthetic |
Drug Class | Small Molecule |
FDA Approval | approved |
C614 | NCI drug code |
C614 | NCI drug code |
LIDOCAINE | GuideToPharmacology Ligand Name |
D0X4RN | TTD Drug ID |