LENVATINIB Drug Record
-
LENVATINIB chembl:CHEMBL1289601 ApprovedAntineoplastic
Alternate Names:
E-7080 ER-203492-00 LENVIMA LENVATINIB KISPLYX E7080 LENVIMA® E 7080 UNII-EE083865G2 4-(3-CHLORO-4-(N'-CYCLOPROPYLUREIDO)PHENOXY)-7-METHOXYQUINOLINE-6-CARBOXAMIDE LENVATINIB MESYLATE 4-{3-CHLORO-4-[(CYCLOPROPYLCARBAMOYL)AMINO]PHENOXY}-7-METHOXYQUINOLINE-6-CARBOXAMIDE chemidplus:417716-92-8 chembl:CHEMBL1289601 rxcui:1603296 drugbank:09078 pubchem.compound:9823820 Drug Info:
FDA Approval not approved Drug Class Small molecule Drug Indications antineoplastic agent FDA Approval Renal cell carcinoma, Thyroid cancer Drug Class Kinase Inhibitors Drug Groups investigational Drug Categories bsep/abcb11 inhibitors Drug Categories cytochrome p-450 cyp1a2 inhibitors Drug Categories cytochrome p-450 cyp1a2 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2b6 inhibitors Drug Categories cytochrome p-450 cyp2b6 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c19 inhibitors Drug Categories cytochrome p-450 cyp2c19 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2c8 inhibitors Drug Categories cytochrome p-450 cyp2c8 inhibitors (moderate) Drug Categories cytochrome p-450 cyp2c9 inhibitors Drug Categories cytochrome p-450 cyp2c9 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp2d6 inhibitors Drug Categories cytochrome p-450 cyp2d6 inhibitors (strength unknown) Drug Categories cytochrome p-450 cyp3a inducers Drug Categories cytochrome p-450 cyp3a inhibitors Drug Categories cytochrome p-450 cyp3a substrates Drug Categories cytochrome p-450 cyp3a4 inducers Drug Categories cytochrome p-450 cyp3a4 inducers (weak) Drug Categories cytochrome p-450 cyp3a4 inhibitors Drug Categories cytochrome p-450 cyp3a4 inhibitors (weak) Drug Categories cytochrome p-450 enzyme inducers Drug Categories cytochrome p-450 enzyme inhibitors Drug Categories cytochrome p-450 substrates Drug Categories heterocyclic compounds, fused-ring Drug Categories kinase inhibitor Drug Categories oat1/slc22a6 inhibitors Drug Categories oat3/slc22a8 inhibitors Drug Categories oatp1b1/slco1b1 inhibitors Drug Categories oct2 inhibitors Drug Categories p-glycoprotein substrates Drug Categories qtc prolonging agents Drug Categories receptor tyrosine kinase inhibitors Drug Categories tyrosine kinase inhibitors Publications:
-
Interaction Score: 0.4
-
Interaction Score: 0.27
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Notes Specific Action of the Ligand Inhibition Endogenous Drug? False -
Interaction Score: 0.25
-
Interaction Score: 0.22
-
Interaction Score: 0.22
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Evidence Type Actionable Approval Status Preclinical Response Type sensitive -
Interaction Score: 0.19
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name E7080 Novel drug target Established target Specific Action of the Ligand Inhibition -
Interaction Score: 0.18
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name E7080 Novel drug target Established target Notes -
Interaction Score: 0.18
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name E7080 Novel drug target Established target -
Interaction Score: 0.17
-
Interaction Score: 0.16
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name E7080 Novel drug target Established target -
Interaction Score: 0.13
-
Interaction Score: 0.08
-
Interaction Score: 0.05
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name E7080 Novel drug target Established target -
Interaction Score: 0.02
-
Alternate Names:
LENVATINIB DrugBank Drug Name 417716-92-8 CAS Number Lenvima Drug Brand Drug Info:
Drug Type small molecule Drug Groups approved Drug Groups investigational -
- Version: 20-Jun-2017
Alternate Names:
LENVATINIB Generic Name Drug Info:
Drug Class Kinase Inhibitors FDA Approval Renal cell carcinoma, Thyroid cancer Publications:
-
- Version: January-2014
Alternate Names:
Drug Info:
Drug Indications antineoplastic agent Drug Class Small molecule FDA Approval not approved Publications:
-
- Version: 27-September-2017
Alternate Names:
Drug Info:
Publications:
-
- Version: 14-September-2020
Alternate Names:
Drug Info:
-
- Version: 02-September-2020
Alternate Names:
CHEMBL1289601 ChEMBL Drug ID Drug Info:
Publications:
-
- Version: 12-May-2016
Alternate Names:
LENVATINIB Primary Drug Name LENVATINIB Drug Generic Name E7081 Drug Synonym Drug Info:
Publications:
-
- Version: 29-September-2020
Alternate Names:
LENVATINIB GuideToPharmacology Ligand Name Drug Info:
Publications:
-
- Version: 2020.06.01
Alternate Names:
D0R0FO TTD Drug ID Drug Info:
Publications:
-
- Version: ChEMBL_27
Alternate Names:
Drug Info:
Publications: