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K-252A Drug Record

  • Summary
  • Interactions
  • Claims
  • K-252A chembl:CHEMBL281948

    Alternate Names:

    K-252A

    Drug Info:

    Drug Categories heterocyclic compounds, fused-ring
    (0 More Sources)

    Publications:

    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Foucart et al., 1990, Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria., Neuropeptides
    Pozzo-Miller, 2006, BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons., Brain Res.
  • K-252A   NPY

    Interaction Score: 3.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2259391


    Sources:
    NCI

  • K-252A   MAP2K1

    Interaction Score: 0.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • K-252A   MET

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • K-252A   BDNF

    Interaction Score: 0.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16797499


    Sources:
    NCI

  • K-252A   CHRM1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    allosteric modulator

    Interaction Info:
    Specific Action of the Ligand Positive
    Endogenous Drug? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • DrugBank: DB02152

    • Version: 5.1.7

    Alternate Names:
    97161-97-2 CAS Number
    CHEMBL281948 ChEMBL ID

    Drug Info:
    Drug Type small molecule
    Drug Groups experimental
    Drug Categories alkaloids

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

  • NCI: K-252A

    • Version: 14-September-2017

    Alternate Names:
    C1382 NCI drug code

    Drug Info:

    Publications:
    Pozzo-Miller, 2006, BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons., Brain Res.
    Foucart et al., 1990, Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria., Neuropeptides

  • ChemblDrugs: chembl:CHEMBL281948

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • GuideToPharmacology: 135652695

    • Version: 29-September-2020

    Alternate Names:

    Drug Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21