DGIdb - K-252A Drug Record

K-252A chembl:CHEMBL281948

Alternate Names:

K-252A

Drug Info:

Drug Categories	heterocyclic compounds, fused-ring

(0 More Sources)

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Foucart et al., 1990, Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria., Neuropeptides
Pozzo-Miller, 2006, BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons., Brain Res.

K-252A NPY

Interaction Score: 3.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2259391

Sources:
NCI
K-252A MAP2K1

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
K-252A MET

Interaction Score: 0.39

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
K-252A BDNF

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16797499

Sources:
NCI
K-252A CHRM1

Interaction Score: 0.07

Interaction Types & Directionality:

allosteric modulator

Interaction Info:

Specific Action of the Ligand Positive

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

DrugBank: DB02152

Version: 5.1.7

Alternate Names:

97161-97-2 CAS Number

CHEMBL281948 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories alkaloids

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: K-252A

Version: 14-September-2017

Alternate Names:

C1382 NCI drug code

Drug Info:

Publications:

Pozzo-Miller, 2006, BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons., Brain Res.

Foucart et al., 1990, Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria., Neuropeptides

ChemblDrugs: chembl:CHEMBL281948
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
GuideToPharmacology: 135652695
- Version: 29-September-2020
Alternate Names:

Drug Info:

Publications:

Drug Type	small molecule
Drug Groups	experimental
Drug Categories	alkaloids

Specific Action of the Ligand	Positive
Endogenous Drug?	False

K-252A Drug Record

K-252A chembl:CHEMBL281948

Alternate Names:

Drug Info:

Publications:

K-252A NPY

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2259391

Sources: NCI

K-252A MAP2K1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

K-252A MET

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

K-252A BDNF

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16797499

Sources: NCI

K-252A CHRM1

Interaction Types & Directionality: allosteric modulator

Interaction Info: Specific Action of the Ligand Positive Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

DrugBank: DB02152

Alternate Names: 97161-97-2 CAS Number CHEMBL281948 ChEMBL ID

Drug Info: Drug Type small molecule Drug Groups experimental Drug Categories alkaloids

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: K-252A

Alternate Names: C1382 NCI drug code

Drug Info:

ChemblDrugs: chembl:CHEMBL281948

Alternate Names:

Drug Info:

Publications:

GuideToPharmacology: 135652695

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
2259391

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
16797499

Sources:
NCI

Interaction Types & Directionality:

allosteric modulator

Interaction Info:

Specific Action of the Ligand Positive

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Alternate Names:

97161-97-2 CAS Number

CHEMBL281948 ChEMBL ID

Drug Info:

Drug Type small molecule

Drug Groups experimental

Drug Categories alkaloids

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

C1382 NCI drug code