DGIdb - IPRATROPIUM Drug Record

IPRATROPIUM chembl:CHEMBL1621597 Approved

Alternate Names:

IPRATROPIUM

Drug Info:

Drug Class	bronchodilator agents
Year of Approval	1986
FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	for treatment of chronic obstructive pulmonary disorder (COPD)

(1 More Sources)

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
Almadhoun K et al., 2020, Bronchodilators,
Wellington, 2005, Ipratropium bromide HFA., Treat Respir Med
Rehder KJ, 2017, Adjunct Therapies for Refractory Status Asthmaticus in Children., Respir Care

IPRATROPIUM CHRM2

Interaction Score: 0.87

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name ipratropium bromide + albuterol sulfate,DuoNeb

Novel drug target Established target

PMIDs:
30085570 15987237 28546381

Sources:
TdgClinicalTrial TEND
IPRATROPIUM CHRM1

Interaction Score: 0.53

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name ipratropium bromide + albuterol sulfate,DuoNeb

Novel drug target Established target

PMIDs:
30085570 15987237 28546381

Sources:
TdgClinicalTrial TEND
IPRATROPIUM CHRM3

Interaction Score: 0.5

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
30085570 15987237 28546381

Sources:
TTD
IPRATROPIUM CYP2C9

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
IPRATROPIUM CYP1A2

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
IPRATROPIUM CYP2D6

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC
IPRATROPIUM CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22931300

Sources:
DTC

TEND: IPRATROPIUM
- Version: 01-August-2011
Alternate Names:

IPRATROPIUM Primary Drug Name

Drug Info:

Year of Approval 1986

Drug Class bronchodilator agents

Publications:
TdgClinicalTrial: IPRATROPIUM
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications for treatment of chronic obstructive pulmonary disorder (COPD)

Drug Class Small Molecule

FDA Approval approved

Publications:
DTC: IPRATROPIUM
- Version: 02-September-2020
Alternate Names:

CHEMBL1621597 ChEMBL Drug ID

Drug Info:

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol
TTD: Ipratropium
- Version: 2020.06.01
Alternate Names:

D0S0AS TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1621597
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	ipratropium bromide + albuterol sulfate,DuoNeb
Novel drug target	Established target

IPRATROPIUM Drug Record

IPRATROPIUM chembl:CHEMBL1621597 Approved

Alternate Names:

Drug Info:

Publications:

IPRATROPIUM CHRM2

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name ipratropium bromide + albuterol sulfate,DuoNeb Novel drug target Established target

PMIDs: 30085570 15987237 28546381

Sources: TdgClinicalTrial TEND

IPRATROPIUM CHRM1

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name ipratropium bromide + albuterol sulfate,DuoNeb Novel drug target Established target

PMIDs: 30085570 15987237 28546381

Sources: TdgClinicalTrial TEND

IPRATROPIUM CHRM3

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 30085570 15987237 28546381

Sources: TTD

IPRATROPIUM CYP2C9

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

IPRATROPIUM CYP1A2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

IPRATROPIUM CYP2D6

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

IPRATROPIUM CYP3A4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22931300

Sources: DTC

TEND: IPRATROPIUM

Alternate Names: IPRATROPIUM Primary Drug Name

Drug Info: Year of Approval 1986 Drug Class bronchodilator agents

Publications:

TdgClinicalTrial: IPRATROPIUM

Alternate Names:

Drug Info: Drug Indications for treatment of chronic obstructive pulmonary disorder (COPD) Drug Class Small Molecule FDA Approval approved

Publications:

DTC: IPRATROPIUM

Alternate Names: CHEMBL1621597 ChEMBL Drug ID

Drug Info:

Publications: Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for &gt;200 compounds., Chem Res Toxicol

TTD: Ipratropium

Alternate Names: D0S0AS TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1621597

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name ipratropium bromide + albuterol sulfate,DuoNeb

Novel drug target Established target

PMIDs:
30085570 15987237 28546381

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name ipratropium bromide + albuterol sulfate,DuoNeb

Novel drug target Established target

PMIDs:
30085570 15987237 28546381

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
30085570 15987237 28546381

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22931300

Sources:
DTC

Alternate Names:

IPRATROPIUM Primary Drug Name

Drug Info:

Year of Approval 1986

Drug Class bronchodilator agents

Drug Info:

Drug Indications for treatment of chronic obstructive pulmonary disorder (COPD)

Drug Class Small Molecule

FDA Approval approved

Alternate Names:

CHEMBL1621597 ChEMBL Drug ID

Publications:

Sakatis MZ et al., 2012, Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., Chem Res Toxicol

Alternate Names:

D0S0AS TTD Drug ID