DGIdb - INTERLEUKIN-10 Drug Record

INTERLEUKIN-10 chembl:CHEMBL4297771

Alternate Names:

IL-10
INTERLEUKIN-10

Drug Info:

(0 More Sources)

Publications:

De et al., 2000, Exaggerated human monocyte IL-10 concomitant to minimal TNF-alpha induction by heat-shock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus., J. Immunol.
Otsuki et al., 2002, IL-10 in myeloma cells., Leuk. Lymphoma
Cheon et al., 2006, Prostaglandin E2 augments IL-10 signaling and function., J. Immunol.
Rust et al., 2005, TIMP-1 expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells., J. Pathol.

INTERLEUKIN-10 OSM

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12148907

Sources:
NCI
INTERLEUKIN-10 IL10RA

Interaction Score: 11.36

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology
INTERLEUKIN-10 HSPB2

Interaction Score: 2.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11034403

Sources:
NCI
INTERLEUKIN-10 PTGER1

Interaction Score: 1.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16818766

Sources:
NCI
INTERLEUKIN-10 ALK

Interaction Score: 0.39

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15920698

Sources:
NCI

GuideToPharmacology: 178101673
- Version: 29-September-2020
Alternate Names:

IL10 Gene Symbol (for Endogenous Peptides)

IL-10 GuideToPharmacology Ligand Name

Drug Info:

Name of the Ligand Species (if a Peptide) Human

Publications:

NCI: IL-10

Version: 14-September-2017

Alternate Names:

C1320 NCI drug code

Drug Info:

Publications:

Cheon et al., 2006, Prostaglandin E2 augments IL-10 signaling and function., J. Immunol.

De et al., 2000, Exaggerated human monocyte IL-10 concomitant to minimal TNF-alpha induction by heat-shock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus., J. Immunol.

Otsuki et al., 2002, IL-10 in myeloma cells., Leuk. Lymphoma

ChemblDrugs: chembl:CHEMBL4297771
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Agonist

IL10	Gene Symbol (for Endogenous Peptides)
IL-10	GuideToPharmacology Ligand Name

INTERLEUKIN-10 Drug Record

INTERLEUKIN-10 chembl:CHEMBL4297771

Alternate Names:

Drug Info:

Publications:

INTERLEUKIN-10 OSM

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12148907

Sources: NCI

INTERLEUKIN-10 IL10RA

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Agonist

PMIDs: None found

Sources: GuideToPharmacology

INTERLEUKIN-10 HSPB2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11034403

Sources: NCI

INTERLEUKIN-10 PTGER1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16818766

Sources: NCI

INTERLEUKIN-10 ALK

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15920698

Sources: NCI

GuideToPharmacology: 178101673

Alternate Names: IL10 Gene Symbol (for Endogenous Peptides) IL-10 GuideToPharmacology Ligand Name

Drug Info: Name of the Ligand Species (if a Peptide) Human

Publications:

NCI: IL-10

Alternate Names: C1320 NCI drug code

Drug Info:

ChemblDrugs: chembl:CHEMBL4297771

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
12148907

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
11034403

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16818766

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15920698

Sources:
NCI

Alternate Names:

IL10 Gene Symbol (for Endogenous Peptides)

IL-10 GuideToPharmacology Ligand Name

Drug Info:

Name of the Ligand Species (if a Peptide) Human

Alternate Names:

C1320 NCI drug code