DGIdb - INOSITOL Drug Record

INOSITOL chembl:CHEMBL1222251

Alternate Names:

NSC-25142
MESO-INOSITOL
NSC-55551
NSC-404118
CYCLOHEXANEHEXOL
INOSITOL
NSC-8101

Drug Info:

(0 More Sources)

Publications:

Pula et al., 2004, Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestin- and clathrin-dependent and is suppressed by receptor inverse agonists., J. Neurochem.
Hauschildt et al., 1988, Role of inositol starvation on ecto-5'-nucleotidase activity during mitogen-induced lymphocyte activation., Immunol. Lett.
Langlois et al., 1994, Regulation by growth factors of angiotensin II type-1 receptor and the alpha subunit of Gq and G11 in bovine adrenal cells., Endocrinology
Müller et al., 1994, Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport., J. Cell Biol.
He et al., 2000, Intracellular Ca(2+) and Ca(2+)/calmodulin-dependent kinase II mediate acute potentiation of neurotransmitter release by neurotrophin-3., J. Cell Biol.
Alberola-Ila et al., 1992, Intracellular events involved in CD5-induced human T cell activation and proliferation., J. Immunol.
Kojima et al., 1997, Characterization of the pleckstrin homology domain of Btk as an inositol polyphosphate and phosphoinositide binding domain., Biochem. Biophys. Res. Commun.
Takeuchi et al., 1998, PTB domain of insulin receptor substrate-1 binds inositol compounds., Biochem. J.
Chowdhury et al., 2004, Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells. Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics., Eur. J. Biochem.
Milligan et al., 1989, Identification of the pertussis and cholera toxin substrates in normal and N-ras transformed NIH3T3 fibroblasts and an assessment of their involvement in bombesin-stimulation of inositol phospholipid metabolism., Oncogene
Weng et al., 1996, Novel CCK-B receptor agonists: diketopiperazine analogues derived for CCK4 bioactive conformation., Regul. Pept.
Olszewska-Pazdrak et al., 2004, Epidermal growth factor potentiates cholecystokinin/gastrin receptor-mediated Ca2+ release by activation of mitogen-activated protein kinases., J. Biol. Chem.
Liepkalns et al., 1991, Cell signalling associated with fibrinolytic ligand binding to human colorectal carcinoma cells., J. Cancer Res. Clin. Oncol.
Iijima et al., 2005, Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA., Proc. Natl. Acad. Sci. U.S.A.
Weglarz et al., 2006, Quantitative analysis of the level of p53 and p21(WAF1) mRNA in human colon cancer HT-29 cells treated with inositol hexaphosphate., Acta Biochim. Pol.

INOSITOL TEC

Interaction Score: 4.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9240435

Sources:
NCI
INOSITOL CD5

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1371522

Sources:
NCI
INOSITOL GRM1

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15140199

Sources:
NCI
INOSITOL IRS1

Interaction Score: 1.26

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9693122

Sources:
NCI
INOSITOL CCKBR

Interaction Score: 0.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8876029 14602717

Sources:
NCI
INOSITOL NT5E

Interaction Score: 0.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2847980

Sources:
NCI
INOSITOL NTF3

Interaction Score: 0.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10811820

Sources:
NCI
INOSITOL LPL

Interaction Score: 0.49

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8063863

Sources:
NCI
INOSITOL CCN2

Interaction Score: 0.46

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15560785

Sources:
NCI
INOSITOL PLG

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1648562

Sources:
NCI
INOSITOL TGFB1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8013389

Sources:
NCI
INOSITOL NRAS

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2498808

Sources:
NCI
INOSITOL BDNF

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16286649

Sources:
NCI
INOSITOL TP53

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16733561

Sources:
NCI

NCI: INOSITOL

Version: 14-September-2017

Alternate Names:

C28163 NCI drug code

Drug Info:

Publications:

Hauschildt et al., 1988, Role of inositol starvation on ecto-5'-nucleotidase activity during mitogen-induced lymphocyte activation., Immunol. Lett.

Müller et al., 1994, Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport., J. Cell Biol.

Alberola-Ila et al., 1992, Intracellular events involved in CD5-induced human T cell activation and proliferation., J. Immunol.

ChemblDrugs: chembl:CHEMBL1222251
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

INOSITOL Drug Record

INOSITOL chembl:CHEMBL1222251

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9240435

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1371522

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15140199

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9693122

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8876029 14602717

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2847980

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10811820

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8063863

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15560785

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1648562

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8013389

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2498808

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16286649

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16733561

Sources: NCI

NCI: INOSITOL

Alternate Names: C28163 NCI drug code

Drug Info:

ChemblDrugs: chembl:CHEMBL1222251

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
9240435

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1371522

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15140199

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9693122

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8876029 14602717

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2847980

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10811820

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8063863

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15560785

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1648562

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8013389

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2498808

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16286649

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16733561

Sources:
NCI

Alternate Names:

C28163 NCI drug code