DGIdb - HYDROXYCAMPTOTHECIN Drug Record

HYDROXYCAMPTOTHECIN chembl:CHEMBL273862

Alternate Names:

10-HYDROXY-CAMPTOTHECIN
IRINOTECAN RELATED COMPOUND A
10-HYDROXYCAMPTOTHECINE
10-HYDROXYCAMPTOTHECIN
10-HYDROXY CAMPTOTHECIN
NSC-107124
HYDROXYCAMPTOTHECIN

Drug Info:

(0 More Sources)

Publications:

Luo Y et al., 2012, Synthesis and biological evaluation of new homocamptothecin analogs., Eur J Med Chem
Li YB et al., 2013, Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents., Eur J Med Chem
Tan H et al., 2015, Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor., Bioorg Med Chem

HYDROXYCAMPTOTHECIN TOP1

Interaction Score: 0.9

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22647222 24012683 25481395

Sources:
DTC
HYDROXYCAMPTOTHECIN HBB

Interaction Score: 0.76

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HYDROXYCAMPTOTHECIN CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DTC: HYDROXYCAMPTOTHECIN

Version: 02-September-2020

Alternate Names:

CHEMBL273862 ChEMBL Drug ID

Drug Info:

Publications:

Tan H et al., 2015, Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor., Bioorg Med Chem

Luo Y et al., 2012, Synthesis and biological evaluation of new homocamptothecin analogs., Eur J Med Chem

Li YB et al., 2013, Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents., Eur J Med Chem

ChemblDrugs: chembl:CHEMBL273862
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications: