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HYDROXYCAMPTOTHECIN Drug Record

  • Summary
  • Interactions
  • Claims
  • HYDROXYCAMPTOTHECIN chembl:CHEMBL273862

    Alternate Names:

    10-HYDROXY-CAMPTOTHECIN
    IRINOTECAN RELATED COMPOUND A
    10-HYDROXYCAMPTOTHECINE
    10-HYDROXYCAMPTOTHECIN
    10-HYDROXY CAMPTOTHECIN
    NSC-107124
    HYDROXYCAMPTOTHECIN

    Drug Info:

    (0 More Sources)

    Publications:

    Luo Y et al., 2012, Synthesis and biological evaluation of new homocamptothecin analogs., Eur J Med Chem
    Li YB et al., 2013, Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents., Eur J Med Chem
    Tan H et al., 2015, Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor., Bioorg Med Chem
  • HYDROXYCAMPTOTHECIN   TOP1

    Interaction Score: 0.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22647222 24012683 25481395


    Sources:
    DTC

  • HYDROXYCAMPTOTHECIN   HBB

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HYDROXYCAMPTOTHECIN   CYP3A4

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DTC: HYDROXYCAMPTOTHECIN

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL273862 ChEMBL Drug ID

    Drug Info:

    Publications:
    Tan H et al., 2015, Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor., Bioorg Med Chem
    Luo Y et al., 2012, Synthesis and biological evaluation of new homocamptothecin analogs., Eur J Med Chem
    Li YB et al., 2013, Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents., Eur J Med Chem

  • ChemblDrugs: chembl:CHEMBL273862

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21